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Protein-tyrosine phosphatase 4A3 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
PentamidineIC5053600.0 [1]
PRL-3 InhibitorIC50900.0 [1]
2-{5-[(E)-(4-Oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzoic acidIC5013300.0 [1], 53000.0 [2]
4-(2-((2,5-Dioxoimidazolidin-4-ylidene)methyl)-1H-pyrrol-1-yl)benzoic acidIC5028100.0 [1], 100000.0 [2]
7-Amino-2-phenyl-5H-thieno[3,2-c]pyridin-4-oneIC50128.0 [1], 240.0 [2]
1-(3,4-Dihydroxyphenyl)-2-{[1-(4-methoxyphenyl)-1H-tetrazol-5-yl]thio}ethanoneIC5044700.0 [1]
2-[[5-(3-Chlorophenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanoneIC5043800.0 [1]
3-(2-{(E)-[1-(3-Chlorophenyl)-2,5-dioxoimidazolidin-4-ylidene]methyl}-1H-pyrrol-1-yl)benzoic acidIC5015400.0 [1]
5-Amino-6-[(Z)-(3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-(4-hydroxyphenyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-oneIC5033200.0 [1]
(2Z)-2-(3,4-Dihydroxybenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-oneIC5011000.0 [1]
N-(4-Butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamideIC5050000.0 [1]
5-(4-Benzyloxy-biphenyl-3-ylmethylene)-2-thioxo-thiazolidin-4-oneIC501700.0 [1]
2-[(E)-2-[5-(4-Chlorophenyl)furan-2-yl]ethenyl]-6-oxo-3-phenyl-4-sulfanyl-1,2-dihydropyrimidine-5-carbonitrileIC5018300.0 [1]
(5Z)-5-[2-(Benzyloxy)-5-bromobenzylidene]-2-thioxo-1,3-thiazolidin-4-oneIC503000.0 [1]
5-(5-Bromo-2-hydroxy-benzylidene)-2-thioxo-thiazolidin-4-oneIC509500.0 [1]
5-(4-Hydroxy-3-methoxybenzylidene)-2-(o-toluidino)thiazol-4(5H)-oneIC5041500.0 [1]
3-[[(5Z)-5-[(3-Chloro-5-ethoxy-4-hydroxyphenyl)methylidene]-3-methyl-4-oxo-1,3-thiazolidin-2-ylidene]amino]benzoic acidIC5040300.0 [1]
(6Z)-6-(3,4-Dihydroxybenzylidene)-7-imino-2-methyl-6,7-dihydro-5H-isoxazolo[2,3-a]pyrimidin-5-oneIC50100000.0 [1]
2-[6-(Pyrazin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]quinolineIC50100000.0 [1]
3-[5-[(Z)-(5-Imino-7-oxo-2-pyridin-3-yl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-ylidene)methyl]furan-2-yl]benzoic acidIC5041700.0 [1]
(5Z)-5-[[3-[3-[(2-Chlorophenyl)methoxy]phenyl]-1-phenylpyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-oneIC5027600.0 [1]
N'-[1-[4-(4-Fluorophenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-2-yl]-N-(pyridin-3-ylmethyl)oxamideIC5050000.0 [1]
N-(Furan-2-ylmethyl)-N'-[1-[4-(4-methoxyphenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-2-yl]oxamideIC5050000.0 [1]
5-(2-(2-Chlorobenzyloxy)-5-bromobenzylidene)-2-thioxothiazolidin-4-oneIC502400.0 [1]
Prop-2-enyl (E)-3-(3-bromo-4-hydroxy-5-methoxyphenyl)-2-cyanoprop-2-enoateIC5031400.0 [1]
2-{[5,6-Di(furan-2-yl)-1,2,4-triazin-3-yl]sulfanyl}-N-(2-nitrophenyl)acetamideIC5057000.0 [1]
5-(5-(Benzo[b]thiophen-3-yl)-2-(benzyloxy)benzylidene)-2-thioxothiazolidin-4-oneIC50900.0 [1]
5-((3-(Benzyloxy)naphthalen-2-yl)methylene)-2-thioxothiazolidin-4-oneIC502000.0 [1]
5-((3-(3,5-Dimethoxybenzyloxy)naphthalen-2-yl)methylene)-2-thioxothiazolidin-4-oneIC503100.0 [1]
5-[1-[3-(Biphenyl-4-ylmethoxy)-naphthalen-2-yl]-methylidene]-2-thioxo-thiazolidin-4-oneIC501900.0 [1]
5-((3-(2-Chloro-6-fluorobenzyloxy)naphthalen-2-yl)methylene)-2-thioxothiazolidin-4-oneIC501700.0 [1]
5-[(5-Bromo-2-phenylmethoxyphenyl)methyl]-2-sulfanylidene-1,3-thiazolidin-4-oneIC504000.0 [1]
(5Z)-5-[[5-[4-(Dimethylamino)phenyl]-2-phenylmethoxyphenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-oneIC503700.0 [1]
5-(5-(Benzofuran-3-yl)-2-(benzyloxy)benzylidene)-2-thioxothiazolidin-4-oneIC501200.0 [1]
Propan-2-yl (Z)-3-(3-bromo-4-hydroxyphenyl)-2-cyanoprop-2-enoateIC50167100.0 [1]
Ethyl (2E)-2-cyano-3-(3,5-dibromo-4-hydroxyphenyl)prop-2-enoateIC50109200.0 [1]
(Z)-5-((2-Methyl-2H-chromen-3-yl)methylene)-2-((E)-styryl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-oneIC5048700.0 [1]
5-(2-(4-Bromobenzyloxy)benzylidene)-2-thioxothiazolidin-4-oneIC501600.0 [1]
5-Amino-3-benzylsulfanyl-6-[(Z)-(3-methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-oneIC5027700.0 [1]
Propan-2-yl (E)-3-(3-bromo-4-hydroxy-5-methoxyphenyl)-2-cyanoprop-2-enoateIC5069400.0 [1]
2-(1,3-Benzothiazol-2-ylamino)-6-phenylpyrimidine-4-carboxylic acidIC5037800.0 [1]
Prop-2-enyl (E)-3-(3-bromo-4-hydroxyphenyl)-2-cyanoprop-2-enoateIC5047800.0 [1]
3-Hydroxy-2-phenyl-[1,3]thiazolo[3,2-a]pyridin-4-ium-8-carboxylic acidIC50102000.0 [1]
[6-(2-Fluorophenyl)-5,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-8-yl] dihydrogen phosphateIC504930.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Protein-tyrosine phosphatase 4A3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Dec2024https://www.aatbio.com/data-sets/protein-tyrosine-phosphatase-4a3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 20). Quest Database™ Protein-tyrosine phosphatase 4A3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-tyrosine-phosphatase-4a3-inhibitors-ic50-ki.
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