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Protein-tyrosine phosphatase 1E Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
PTP CD45 InhibitorIC507000.0 [1], 30000.0 [2]
2-Aminophenanthrene-9,10-dioneIC504700.0 [1], 30000.0 [2]
Benzo[h]quinoline-5,6-dioneIC5014000.0 [1], 30000.0 [2]
Methyl 4-[(9,10-dioxophenanthren-1-yl)amino]-4-oxobutanoateIC504400.0 [1], 30000.0 [2]
7-[(9,10-Dioxo-9,10-dihydrophenanthrene-2-yl)carbamoyl]heptanoic acid methyl esterIC509900.0 [1], 30000.0 [2]
[(9,10-Dioxo-9,10-dihydrophenanthrene-2-ylcarbonyl)amino]acetic acidIC5015000.0 [1], 30000.0 [2]
Methyl 4-[[7-[(4-methoxy-4-oxobutanoyl)amino]-9,10-dioxophenanthren-2-yl]amino]-4-oxobutanoateIC5012000.0 [1], 30000.0 [2]
N-(9,10-Dioxo-9,10-dihydro-phenanthren-2-yl)-2-fluoro-benzamideIC50600.0 [1], 20000.0 [2]
CID 25262525IC5036800.0 [1]
6-Hydroxy-1-methyl-3-[1-[3-oxo-3-(4-phenylanilino)propyl]triazol-4-yl]-2-phenylindole-5-carboxylic acidIC5020300.0 [1]
CID 71734765IC50390.0 [1]
N-(4-Butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamideIC5050000.0 [1]
1,1,1,3,3,3-Hexafluoro-2-phenylpropan-2-olIC50500000.0 [1]
6-Hydroxy-2-phenyl-3-[2-[3-(trifluoromethyl)phenyl]ethynyl]benzofuran-5-carboxylic acidIC501300.0 [1]
3-[2-(3,5-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC501900.0 [1]
6-Hydroxy-2-phenyl-3-[2-[4-(trifluoromethoxy)phenyl]ethynyl]benzofuran-5-carboxylic acidIC501600.0 [1]
N'-[1-[4-(4-Fluorophenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-2-yl]-N-(pyridin-3-ylmethyl)oxamideIC5050000.0 [1]
N-(Furan-2-ylmethyl)-N'-[1-[4-(4-methoxyphenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-2-yl]oxamideIC5050000.0 [1]
Lyp-IN-1IC502900.0 [1]
N-[(4-Fluorophenyl)methyl]-2-[6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxyacetamideIC5020000.0 [1]
3-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)naphthalen-2-olIC50127900.0 [1]
N-Cyclopropyl-2-[6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxyacetamideIC5020000.0 [1]
N-(9H-Fluoren-9-yl)-2-[6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxyacetamideIC505600.0 [1]
2-[6-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxy-N-naphthalen-1-ylacetamideIC5020000.0 [1]
N-(1,3-Benzothiazol-2-yl)-2-[6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxyacetamideIC509900.0 [1]
2-[6-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxy-N-(4-propan-2-ylphenyl)acetamideIC506500.0 [1]
N-(1-Adamantyl)-2-[6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxyacetamideIC507400.0 [1]
2-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-5-phenylphenolIC50500000.0 [1]
2-[6-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxy-N-(4-morpholin-4-ylphenyl)acetamideIC5020000.0 [1]
2-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-4-phenylphenolIC50500000.0 [1]
N-Benzyl-2-[6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxyacetamideIC5020000.0 [1]
2-[6-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxy-N-(4-phenylphenyl)acetamideIC502800.0 [1]
2-[6-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxy-N'-(4-methylphenyl)sulfonylacetohydrazideIC5014900.0 [1]
N,N-Diethyl-2-[6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxyacetamideIC5020000.0 [1]
2-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-6-phenylphenolIC50448800.0 [1]
N-[(3,4-Dimethoxyphenyl)methyl]-2-[6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxyacetamideIC5020000.0 [1]
2-[6-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxy-N,N-diphenylacetamideIC5012400.0 [1]
N-[2-(2,4-Dichlorophenyl)ethyl]-2-[6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxyacetamideIC504300.0 [1]
2-[6-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxy-N-phenylacetamideIC5020000.0 [1]
2-[6-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxy-N-propylacetamideIC5020000.0 [1]
2-[6-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-7-hydroxynaphthalen-2-yl]oxy-1-phenothiazin-10-ylethanoneIC502200.0 [1]
2-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-4-methylphenolIC50454300.0 [1]
2-(2-Hydroxy-1,1,1,3,3,3-hexafluoropropyl)-1-naphtholIC50500000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Protein-tyrosine phosphatase 1E Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/protein-tyrosine-phosphatase-1e-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Protein-tyrosine phosphatase 1E Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-tyrosine-phosphatase-1e-inhibitors-ic50-ki.
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