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Protein-tyrosine phosphatase 1C Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Oleanolic acidIC5014190.0 [1], 31330.0 [2], 120000.0 [3]
5-[(3-Carboxy-4-hydroxy-5-phenylphenyl)methyl]-2-hydroxy-3-phenylbenzoic acidIC5051000.0 [1]
3-[(3-Carboxy-2-hydroxy-5-phenylphenyl)methyl]-2-hydroxy-5-phenylbenzoic acidIC5037000.0 [1]
3-[(3-Carboxy-2-hydroxy-5-phenylphenyl)methyl]-2-hydroxy-5-phenylbenzoic acidKi9700.0 [1]
EnoxoloneIC5065400.0 [1]
Ursolic acidIC5025780.0 [1]
Tanshinone IIAIC502140.0 [1]
Tanshinone IIC501970.0 [1]
Estramustine phosphateIC5040400.0 [1]
CelastrolIC5027800.0 [1]
Maslinic acidIC5040000.0 [1]
CryptotanshinoneIC5039500.0 [1]
Polyestradiol phosphateIC50300000.0 [1]
Corosolic acidIC5024560.0 [1]
Dihydrotanshinone IIC503670.0 [1]
8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonic acidIC50355.0 [1]
5-((E)-2-{4-[(E)-2-(3-Carboxy-4-hydroxyphenyl)vinyl]-phenyl}vinyl)-2-hydroxybenzoic acidIC5019000.0 [1]
2-(Oxalyl-amino)-benzoic acidKi510000.0 [1]
2-(Oxalyl-amino)-4,5,6,7-tetrahydro-thieno[2,3-C]pyridine-3-carboxylic acidKi2000000.0 [1]
(4As,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-(3-carboxy-3-methylbutanoyl)oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acidIC5012360.0 [1]
3,4,6-Tribromo-5-[(2,3,6-tribromo-4,5-dihydroxyphenyl)methyl]benzene-1,2-diolIC5050000.0 [1]
Cefsulodin sodium saltIC5021000.0 [1]
6-Hydroxy-1-methyl-3-[1-[3-oxo-3-(4-phenylanilino)propyl]triazol-4-yl]-2-phenylindole-5-carboxylic acidIC5015700.0 [1]
2-Hydroxy-3-[(2-nitrophenyl)diazenyl]-1H-indole-5-sulfonic acidIC5068000.0 [1]
CID 71734765IC50910.0 [1]
5-Iodo-2-(oxaloamino)benzoic acidKi80000.0 [1]
6-(Oxalyl-amino)-1H-indole-5-carboxylic acidKi16000.0 [1]
2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-C]pyran-3-carboxylic acidKi350000.0 [1]
2-(Carboxyformamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acidKi100000.0 [1]
1H-Indole-7-carboxylic acid, 6-[(carboxycarbonyl)amino]-Ki28000.0 [1]
2-(Carboxyformamido)thiophene-3-carboxylic acidKi60000.0 [1]
3-(Carboxyformamido)thiophene-2-carboxylic acidKi2000000.0 [1]
3-[(3-Acetyl-2-methyl-1-benzofuran-5-yl)sulfamoyl]benzoic acidIC5085000.0 [1]
(1R,2R,11R,14R,15S,18S,23S)-2,10,10,14,15,21,21-Heptamethyl-5,8-diazahexacyclo[12.12.0.02,11.04,9.015,24.018,23]hexacosa-4,6,8,24-tetraene-18-carboxylic acidIC5040000.0 [1]
(1R,2R,15R,18R,19S,22S,27S)-2,14,14,18,19,25,25-Heptamethyl-5,12-diazaheptacyclo[16.12.0.02,15.04,13.06,11.019,28.022,27]triaconta-4,6,8,10,12,28-hexaene-22-carboxylic acidIC5040000.0 [1]
4-[5-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]thiophen-2-yl]anilineIC50120000.0 [1]
4-[3-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]anilineIC50120000.0 [1]
1-[[2,5-Diethoxy-4-(methanesulfonamido)phenyl]methyl]-3-(4-methoxyphenyl)ureaIC509080.0 [1]
Methyl 2-[4-[[4-[benzyl(methylsulfonyl)amino]-N-benzylsulfonylanilino]methyl]-N-methylsulfonylanilino]acetateIC509610.0 [1]
3-[[5-[(4-Fluorophenyl)methylsulfamoyl]-2-hydroxy-1H-indol-3-yl]diazenyl]benzoic acidIC5018300.0 [1]
5-[[2,5-Diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-ethoxy-N-(4-methylphenyl)benzamideIC502940.0 [1]
(5Z)-5-[[2-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-5-bromophenyl]methylidene]-1,3-thiazolidine-2,4-dioneKi2200.0 [1]
(1R,2S,5S,10S,14R,15R,23R)-1,2,8,8,15,22,22-Heptamethyl-20-phenyl-19,20-diazahexacyclo[12.11.0.02,11.05,10.015,23.017,21]pentacosa-11,17(21),18-triene-5-carboxylic acidIC5040000.0 [1]
(1R,2S,5S,10S,14R,15R,23R)-1,2,8,8,15,22,22-Heptamethyl-19,20-diazahexacyclo[12.11.0.02,11.05,10.015,23.017,21]pentacosa-11,17(21),18-triene-5-carboxylic acidIC5040000.0 [1]
[3-[3-[(3S)-3-(Methylcarbamoyl)-7-(sulfoamino)-3,4-dihydro-1H-isoquinolin-2-yl]-3-oxopropyl]phenyl]sulfamic acidIC50203000.0 [1]
6-Hydroxy-2-phenyl-3-[2-[3-(trifluoromethyl)phenyl]ethynyl]benzofuran-5-carboxylic acidIC502300.0 [1]
3-[2-(3,5-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC502300.0 [1]
6-Hydroxy-2-phenyl-3-[2-[4-(trifluoromethoxy)phenyl]ethynyl]benzofuran-5-carboxylic acidIC502490.0 [1]
6-Hydroxy-2-phenyl-3-(2-phenylethynyl)benzofuran-5-carboxylic acidIC504900.0 [1]
3-[2-(3-Fluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC504200.0 [1]
3-[2-(3-Chlorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC503400.0 [1]
6-Hydroxy-3-[2-(3-methoxyphenyl)ethynyl]-2-phenyl-benzofuran-5-carboxylic acidIC5034000.0 [1]
3-[2-(2,4-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acidIC502600.0 [1]
6-Hydroxy-3-[2-(4-phenoxyphenyl)ethynyl]-2-phenyl-benzofuran-5-carboxylic acidIC50760.0 [1]
3-Ethynyl-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC5050000.0 [1]
(2R)-2-[2,6-Dibromo-4-(6-bromonaphtho[3,2-b][1]benzofuran-11-yl)phenoxy]-3-phenylpropanoic acidIC509000.0 [1]
2-(3-Bromoanilino)-5-hydroxybenzothiazole-6-carboxylic acidIC5078000.0 [1]
[[4-[[4-[[4-[Difluoro(phosphono)methyl]phenyl]methoxy]phenoxy]methyl]phenyl]-difluoromethyl]phosphonic acidIC506300.0 [1]
2-[2,6-Dibromo-4-(6-bromonaphtho[3,2-b][1]benzothiol-11-yl)phenoxy]acetic acidIC505000.0 [1]
[[4-[[3-[[4-[Difluoro(phosphono)methyl]phenyl]methoxy]phenoxy]methyl]phenyl]-difluoromethyl]phosphonic acidIC5016000.0 [1]
Dithiolan-4-yl 4-[6-(4-methoxybenzoyl)oxyhex-1-ynyl]benzoateIC505130.0 [1]
6-[4-(Dithiolan-4-yloxycarbonyl)phenyl]hex-5-ynyl 3-methoxybenzoateIC5038420.0 [1]
6-[4-(Dithiolan-4-yloxycarbonyl)phenyl]hex-5-ynyl 2-methoxybenzoateIC5019250.0 [1]
6-[4-(Dithiolan-4-yloxycarbonyl)phenyl]hex-5-ynyl 2-fluorobenzoateIC508670.0 [1]
6-[4-(Dithiolan-4-yloxycarbonyl)phenyl]hex-5-ynyl 3-fluorobenzoateIC5010000.0 [1]
Dithiolan-4-yl 4-[6-(4-fluorobenzoyl)oxyhex-1-ynyl]benzoateIC509210.0 [1]
6-[4-(Dithiolan-4-yloxycarbonyl)phenyl]hex-5-ynyl 2-nitrobenzoateIC509250.0 [1]
6-[4-(Dithiolan-4-yloxycarbonyl)phenyl]hex-5-ynyl 3-nitrobenzoateIC5023650.0 [1]
Dithiolan-4-yl 4-[6-(4-nitrobenzoyl)oxyhex-1-ynyl]benzoateIC5024880.0 [1]
3-[4-(Dithiolan-4-yloxycarbonyl)phenoxy]propyl 2,5-dibromobenzoateIC5032240.0 [1]
6-[4-(Dithiolan-4-yloxycarbonyl)phenyl]hexyl 2,5-dibromobenzoateIC5011120.0 [1]
4-[4-(Dithiolan-4-yloxycarbonyl)phenyl]but-3-ynyl 2,5-dibromobenzoateIC5015680.0 [1]
2-Hydroxy-4-[1-(cyclohexylcarbamoyl)pentyloxy]-5-[2-(trifluoromethoxy)phenylethynyl]benzoic acidIC508000.0 [1]
1-(4-Bromophenyl)-3-[[2,5-diethoxy-4-(methanesulfonamido)phenyl]methyl]ureaIC502310.0 [1]
2-[4-[[2-(4-Iodoanilino)-2-oxoacetyl]amino]anilino]-2-oxo-1-phenylethanesulfonic acidIC507300.0 [1]
2-Oxo-2-[4-[[2-oxo-2-(4-phenylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acidIC504800.0 [1]
2-Oxo-2-[4-[[2-oxo-2-(4-propan-2-ylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acidIC506000.0 [1]
Methyl 2-[4-[[4-[[benzyl(methylsulfonyl)amino]methyl]-N-(4-ethoxyphenyl)sulfonylanilino]methyl]-N-methylsulfonylanilino]acetateIC502310.0 [1]
Methyl 2-[4-[[N-benzylsulfonyl-4-[(4-ethoxyphenyl)sulfonylamino]anilino]methyl]-N-ethylsulfonylanilino]acetateIC5011360.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[6-(4-propoxyphenyl)pyridin-2-yl]-1,2,4-oxadiazoleIC50120000.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[5-(3-methylphenyl)thiophen-2-yl]-1,2,4-oxadiazoleIC50120000.0 [1]
3-[5-(4-Ethylphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazoleIC50120000.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[5-(4-propylphenyl)thiophen-2-yl]-1,2,4-oxadiazoleIC50120000.0 [1]
3-[5-(4-Butylphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazoleIC50120000.0 [1]
3-[5-(4-Ethoxyphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazoleIC50120000.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[5-(4-propoxyphenyl)thiophen-2-yl]-1,2,4-oxadiazoleIC50120000.0 [1]
Methyl 4-[4-[5-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]thiophen-2-yl]phenoxy]butanoateIC50120000.0 [1]
3-(5-Bromothiophen-2-yl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazoleIC50120000.0 [1]
3-(3-Bromophenyl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazoleIC50120000.0 [1]
4-[3-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]phenolIC50120000.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[3-(2-methylphenyl)phenyl]-1,2,4-oxadiazoleIC50120000.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[3-(3-methylphenyl)phenyl]-1,2,4-oxadiazoleIC50120000.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[3-(4-propylphenyl)phenyl]-1,2,4-oxadiazoleIC50120000.0 [1]
3-[3-(4-Butylphenyl)phenyl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazoleIC50120000.0 [1]
3-(6-Bromopyridin-2-yl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazoleIC50120000.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[5-(2-methylphenyl)thiophen-2-yl]-1,2,4-oxadiazoleIC50120000.0 [1]
3-[3-(4-Ethoxyphenyl)phenyl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazoleIC50120000.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[3-(4-propoxyphenyl)phenyl]-1,2,4-oxadiazoleIC50120000.0 [1]
Methyl 4-[4-[3-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]phenoxy]butanoateIC50120000.0 [1]
5-(1H-Indol-3-ylmethyl)-3-[6-(2-methylphenyl)pyridin-2-yl]-1,2,4-oxadiazoleIC50120000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Protein-tyrosine phosphatase 1C Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/protein-tyrosine-phosphatase-1c-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Protein-tyrosine phosphatase 1C Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-tyrosine-phosphatase-1c-inhibitors-ic50-ki.
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