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Protein phosphatase 2C alpha Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
Microcystin-LRIC503.0 [1]
5,7-Dichloro-4-((3-(4-methoxyphenylthio)benzyl)(methyl)amino)quinoline-2-carboxylic acidIC5021000.0 [1]
(1E)-1-[Amino-(phenanthren-9-ylamino)methylidene]-2-methylguanidineIC5020000.0 [1]
(2S)-2-[[(2R)-2-[[2-[[(4R)-4-[[(2S,3S,4E,6E,8S,9S)-3-Acetamido-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoyl]amino]-4-carboxybutanoyl]-methylamino]acetyl]amino]propanoyl]amino]-4-methylpentanoic acidIC50230000.0 [1]
[(2R)-2-[(4As,7R,7aR)-2,4a-dihydroxy-7a-methoxy-5-oxo-2,3,4,7-tetrahydrofuro[3,4-b]pyran-7-yl]-2-hydroxyethyl] hexadecanoateIC5011000.0 [1]
[(2R)-2-[(5S,8R)-6,9-Dioxo-2-propan-2-yloxy-1,7-dioxaspiro[4.4]nonan-8-yl]-2-hydroxyethyl] hexadecanoateIC503000.0 [1]
4-[[4-[(E)-[5-[4-(Dimethylamino)phenyl]-6-ethoxycarbonyl-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]methyl]benzoic acidIC5067800.0 [1]
2-[[6-(1,3-Dioxoisoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]-N-[5-[(3-methylphenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]acetamideIC5031800.0 [1]
(2R)-2-[[(2S,3S,4E,6E,8S,9S)-3-Acetamido-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoyl]amino]-5-[[2-[[(1R)-1-carboxyethyl]amino]-2-oxoethyl]-methylamino]-5-oxopentanoic acidIC50400000.0 [1]
(2R)-2-[[(2S,3S,4E,6E,8S,9S)-3-Amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoyl]amino]-5-[[2-[[(1R)-1-carboxyethyl]amino]-2-oxoethyl]-methylamino]-5-oxopentanoic acidIC50280000.0 [1]
(2R)-2-[[(2S,3S,4E,6E,8S,9S)-3-Acetamido-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoyl]amino]-5-(dimethylamino)-5-oxopentanoic acidIC50100000.0 [1]
Methyl (2R)-2-[[(2S,3S,4E,6E,8S,9S)-3-acetamido-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoyl]amino]-5-(dimethylamino)-5-oxopentanoateIC50100000.0 [1]
(2R)-2-[[(2S,3S,4E,6E,8S,9S)-3-Amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoyl]amino]-5-[[3-[[(1R)-1-carboxyethyl]amino]-3-oxoprop-1-en-2-yl]-methylamino]-5-oxopentanoic acidIC5045000.0 [1]
(2R)-2-[[(2S,3S,4E,6E,8S,9S)-3-Acetamido-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoyl]amino]-5-[[3-[[(1R)-1-carboxyethyl]amino]-3-oxoprop-1-en-2-yl]-methylamino]-5-oxopentanoic acidIC50140000.0 [1]
(2S)-2-[[(2R)-2-[2-[[(4R)-4-[[(2S,3S,4E,6E,8S,9S)-3-Acetamido-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoyl]amino]-4-carboxybutanoyl]-methylamino]prop-2-enoylamino]propanoyl]amino]-4-methylpentanoic acidIC5075000.0 [1]
4-({4-[(E)-(1-Ethyl-2,5-dioxoimidazolidin-4-ylidene)methyl]-2-iodophenoxy}methyl)benzoic acidIC5042500.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Protein phosphatase 2C alpha Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/protein-phosphatase-2c-alpha-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Protein phosphatase 2C alpha Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-phosphatase-2c-alpha-inhibitors-ic50-ki.
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