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Protein phosphatase 1D Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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▼
Standard Type
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Standard Values (in nM)
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▼
(1R,3R,4As,4bR,6R,8R,8aS,10S,10aS)-10-[tert-butyl(dimethyl)silyl]oxy-1-(hydroxymethyl)-1,4a,6-trimethyl-8-triethylsilyloxy-2,3,4,4b,5,6,7,8,8a,9,10,10a-dodecahydrophenanthren-3-olIC5086.9 [1], 480.0 [2]
(1R,3S,4As,5R,8aR)-3-[tert-butyl(dimethyl)silyl]oxy-1-methyl-5-triethylsilyloxy-3,4,4a,5,6,7,8,8a-octahydro-2H-naphthalene-1-carboxylic acidIC50110.0 [1]
(1R,3S,4As,5R,8aR)-3-[tert-butyl(dimethyl)silyl]oxy-1-methyl-5-triethylsilyloxy-3,4,4a,5,6,7,8,8a-octahydro-2H-naphthalene-1-carboxylic acidKi228.0 [1]
5-[[(5-Chloro-2-methylpyridin-3-yl)amino]methyl]-N-[(2S)-3-cyclopentyl-1-(cyclopropylamino)-1-oxopropan-2-yl]thiophene-2-carboxamideIC5086.3 [1]
4-[4-(2-Oxo-3H-1,3-benzoxazol-6-yl)-1,3-thiazol-2-yl]benzonitrileIC5020000.0 [1]
6-[2-[4-Fluoro-3-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-(4-Fluoro-3-hydroxyphenyl)-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-(4-Fluoro-2-methoxyphenyl)-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
3-[2-(Dimethylamino)ethyl]-6-[2-(4-fluoro-2-methylphenyl)-1,3-thiazol-4-yl]-1H-benzimidazol-2-oneIC5020000.0 [1]
[(1R,3S,4As,5R,8aR)-3-[tert-butyl(dimethyl)silyl]oxy-1-methyl-5-triethylsilyloxy-3,4,4a,5,6,7,8,8a-octahydro-2H-naphthalen-1-yl]methanolIC50215.0 [1]
6-[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-(4-Methylphenyl)-1,3-thiazol-4-yl]-2,3-dihydro-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-(2-Phenyl-1,3-thiazol-4-yl)-2,3-dihydro-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-(3-Fluorophenyl)-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-(2-Pyridin-4-yl-1,3-thiazol-4-yl)-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-(4-Fluoro-3-methylphenyl)-1,3-thiazol-4-yl]-2,3-dihydro-1,3-benzoxazol-2-oneIC5020000.0 [1]
5-[2-(4-Fluoro-2-methylphenyl)-1,3-thiazol-4-yl]-1,3-dihydrobenzimidazol-2-oneIC5020000.0 [1]
6-[2-(4-Fluoro-2-methylphenyl)-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC50100000.0 [1]
5-[2-(4-Fluoro-2-methylphenyl)-1,3-thiazol-4-yl]-1,3-dihydroindol-2-oneIC5020000.0 [1]
6-[2-(2-Ethyl-4-fluorophenyl)-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-[4-Fluoro-2-(hydroxymethyl)phenyl]-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-[2-[(Dimethylamino)methyl]-4-fluorophenyl]-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-[4-Fluoro-2-(morpholin-4-ylmethyl)phenyl]-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-[2-[2-(Dimethylamino)ethyl]-4-fluorophenyl]-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-[4-Fluoro-2-(2-methoxyethoxymethyl)phenyl]-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-[2-(2-Aminoethoxymethyl)-4-fluorophenyl]-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
6-[2-[4-Fluoro-2-(2-pyrrolidin-1-ylethoxymethyl)phenyl]-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
3-[2-(Dimethylamino)ethyl]-5-[2-(4-fluoro-2-methylphenyl)-1,3-thiazol-4-yl]-1H-benzimidazol-2-oneIC5020000.0 [1]
6-[2-(3,4-Difluorophenyl)-1,3-thiazol-4-yl]-3H-1,3-benzoxazol-2-oneIC5020000.0 [1]
5-[2-[4-Fluoro-2-(2-methoxyethoxymethyl)phenyl]-1,3-thiazol-4-yl]-1,3-dihydrobenzimidazol-2-oneIC5020000.0 [1]
3-[(3R,5S,8S,11S,14S,17S,20S)-20-Benzyl-14-[(2S)-butan-2-yl]-3-carbamoyl-8-(carboxymethyl)-6,9,12,15,18,21-hexaoxo-17-(phosphonooxymethyl)-11-[(4-phosphonooxyphenyl)methyl]-1-thia-4,7,10,13,16,19-hexazacyclodocos-5-yl]propanoic acidKi150.0 [1]
6-[2-(4-Fluorophenyl)-1,3-thiazol-4-yl]-2,3-dihydro-1,3-benzoxazol-2-oneIC5023000.0 [1]
Items per page: 1 - 10 of 32
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References

This online tool may be cited as follows

MLA

"Quest Database™ Protein phosphatase 1D Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/protein-phosphatase-1d-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Protein phosphatase 1D Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-phosphatase-1d-inhibitors-ic50-ki.
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