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Protein kinase N1 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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▼
Standard Type
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Standard Values (in nM)
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▼
StaurosporineIC501.0 [1], 1.2 [2]
QuercetinIC505800.0 [1]
FasudilIC501700.0 [1]
NorlichexanthoneIC5054900.0 [1]
(4S,6Z,9S,10S)-9,10,18-Trihydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,15,17-tetraene-2,8-dioneIC5010000.0 [1]
CID 44814409IC504900.0 [1]
2,3,6,8-Tetrahydroxy-1-methylxanthoneIC5045300.0 [1]
Epicoccolide BIC509000.0 [1]
Astrogorgiadiol BIC50100000.0 [1]
(1S,9R)-5,6,12,13,14-Pentahydroxy-4,11-dimethyl-16-oxo-8,17-dioxatetracyclo[7.7.1.02,7.010,15]heptadeca-2(7),3,5,10,12,14-hexaene-3-carbaldehydeIC504480.0 [1]
(1R,3As,4S,5R,7aR)-4-[2-(5-hydroxy-2-methylphenyl)ethyl]-7a-methyl-1-[(2R)-6-methyl-5-methylideneheptan-2-yl]-1,2,3,3a,4,5,6,7-octahydroinden-5-olIC50100000.0 [1]
Calicoferol BIC50100000.0 [1]
N'-(3-Pyridin-4-yl-2,6-naphthyridin-1-yl)ethane-1,2-diamineIC507.0 [1]
Calicoferol EIC50100000.0 [1]
cis-3-[4-Amino-7-(3-azetidin-1-ylmethyl-cyclobutyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-phenolIC502600.0 [1]
2-Methyl-N~1~-[3-(Pyridin-4-Yl)-2,6-Naphthyridin-1-Yl]propane-1,2-DiamineIC5035.0 [1]
5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamideIC5010000.0 [1]
7,8-Dichloro-9-methyl-1-oxospiro[2,4-dihydropyrido[3,4-b]indole-3,4'-piperidine]-4-carbonitrileIC50310.0 [1]
9-Cyclopentyl-N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-purine-2,8-diamineIC506100.0 [1]
6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-oneIC5010000.0 [1]
2-Anilino-7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-oneIC5010000.0 [1]
(8S,16S)-3,16-Dihydroxy-9,10-seco-1,3,5(10)-cholestatrien-9-oneIC50100000.0 [1]
Calicoferol AIC50100000.0 [1]
(1R,3As,4S,7aR)-4-[2-(5-hydroxy-2-methylphenyl)ethyl]-7a-methyl-1-[(2R)-6-methyl-5-methylideneheptan-2-yl]-2,3,3a,4,6,7-hexahydro-1H-inden-5-oneIC50100000.0 [1]
Methyl 3-[[(1R,2S,4aR,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]-4,5-dihydroxybenzoateIC50100000.0 [1]
2-Methyl-1-N-(2-pyridin-4-ylpyrido[3,4-d]pyrimidin-4-yl)propane-1,2-diamineIC5099.0 [1]
2-(1H-Indazol-5-yl)-4-piperazin-1-ylquinazolineIC50990.0 [1]
3-(1H-Indazol-5-yl)-1-piperazin-1-ylisoquinolineIC501000.0 [1]
N'-[2-(1H-Indazol-5-yl)quinazolin-4-yl]ethane-1,2-diamineIC501000.0 [1]
N'-[2-(1H-Indazol-5-yl)quinazolin-4-yl]propane-1,3-diamineIC501000.0 [1]
2-(1H-Indazol-5-yl)-4-(4-methylpiperazin-1-yl)quinazolineIC501000.0 [1]
(4S,6Z,10S)-10,18-Dihydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,15,17-tetraene-2,8-dioneIC5010000.0 [1]
(1R,3As,4S,5S,7aR)-4-[2-(5-hydroxy-2-methylphenyl)ethyl]-7a-methyl-1-[(E,2R)-6-methylhept-3-en-2-yl]-1,2,3,3a,4,5,6,7-octahydroinden-5-olIC50100000.0 [1]
Infigratinib phosphateIC5010000.0 [1]
7-[3-(Azetidin-1-ylmethyl)cyclobutyl]-5-[3-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl]pyrrolo[2,3-d]pyrimidin-4-amineIC509700.0 [1]
1-[4-[3-[4-Amino-5-[2-fluoro-5-[[(2S)-oxolan-2-yl]methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanoneIC5010000.0 [1]
1-[4-[3-[4-Amino-5-[2-fluoro-3-[[(2S)-oxolan-2-yl]methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanoneIC5010000.0 [1]
1-[(3-Hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea;methanesulfonic acidIC501.0 [1]
5,6,7-Trihydroxy-3-methoxy-4-methyl-3H-2-benzofuran-1-oneIC5030000.0 [1]
3-[[(1R,2S,4Ar,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]-4-hydroxy-5-(3-methylbutylamino)cyclohexa-3,5-diene-1,2-dioneIC50100000.0 [1]
CID 76324771IC5030000.0 [1]
4-Methyl-5,6,7-trihydroxy-1,3-dihydroisobenzofuran-1-oneIC5018600.0 [1]
7-[[(1R,2S,4Ar,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]-5-methoxy-2-methyl-1,3-benzoxazol-6-olIC50100000.0 [1]
N~1~-[2-(1h-Indazol-5-Yl)pyrido[3,4-D]pyrimidin-4-Yl]-2-Methylpropane-1,2-DiamineIC50547.0 [1]
9-[[8-Fluoro-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-4-methyl-[1,4]oxazino[3,2-c]quinolin-3-oneIC5030000.0 [1]
2-(1H-Indazol-5-yl)-4-piperazin-1-ylpyrido[3,4-d]pyrimidineIC501000.0 [1]
Items per page: 1 - 10 of 46
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References

This online tool may be cited as follows

MLA

"Quest Database™ Protein kinase N1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/protein-kinase-n1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Protein kinase N1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-kinase-n1-inhibitors-ic50-ki.
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