Protein arginine N-methyltransferase 8 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	N,N,N'-Trimethylethylenediamine	IC50	7000.0 [1]
	CID 91668547	IC50	223.0 [1]
	CID 53868701	IC50	1600.0 [1]
	MS023	IC50	4.0 [1]
	PRMT5 Inhibitor C17	IC50	100000.0 [1]
	N,N'-Dimethyl-N'-[[5-[3-(2-phenylethoxy)-5-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]methyl]ethane-1,2-diamine	IC50	23.0 [1]
	N'-[[5-[3-(2-Cyclohexylethoxy)-5-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]methyl]-N,N'-dimethylethane-1,2-diamine	IC50	21.0 [1]
	N,N'-Dimethyl-N'-[[5-(4-propan-2-yloxyphenyl)-1H-pyrazol-4-yl]methyl]ethane-1,2-diamine	IC50	14.0 [1]
	N'-[[5-(3-Chloro-4-propan-2-yloxyphenyl)-1-methylpyrazol-4-yl]methyl]-N,N'-dimethylethane-1,2-diamine	IC50	22.0 [1]
	N'-Methyl-N'-[[5-[4-(2-methylpropyl)phenyl]-1H-pyrazol-4-yl]methyl]ethane-1,2-diamine	IC50	10.0 [1]
	N'-[[5-(3-Chloro-4-propan-2-yloxyphenyl)-1H-pyrazol-4-yl]methyl]-N'-methylethane-1,2-diamine	IC50	7.0 [1]
	N'-Methyl-N'-[[5-[4-(3-morpholin-4-ylpropoxy)phenyl]-1H-pyrazol-4-yl]methyl]ethane-1,2-diamine	IC50	450.0 [1]
	N'-Methyl-N'-[[5-(4-phenoxyphenyl)-1H-pyrazol-4-yl]methyl]ethane-1,2-diamine	IC50	2.0 [1]
	1-[4-[4-[4-[[2-Aminoethyl(methyl)amino]methyl]-1H-pyrazol-5-yl]phenyl]piperazin-1-yl]-2-phenylethanone	IC50	1500.0 [1]
	N'-[[5-(3-Chloro-4-propan-2-yloxyphenyl)-1H-pyrazol-4-yl]methyl]-N,N'-dimethylethane-1,2-diamine	IC50	10.0 [1]
	N-Methyl-2-[4-[5-[[methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-4-yl]phenoxy]benzamide	IC50	65.0 [1]
	N,N-Dimethyl-3-[4-[4-[[methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-5-yl]phenoxy]benzamide	IC50	179.0 [1]
	N,N-Dimethyl-3-[4-[5-[[methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-4-yl]phenoxy]benzamide	IC50	347.0 [1]
	(2E)-2-[(E)-3-[1,1-Dimethyl-3-(3-phenylpropyl)benzo[e]indol-3-ium-2-yl]prop-2-enylidene]-1,1-dimethyl-3-(3-phenylpropyl)benzo[e]indole;bromide	IC50	1740.0 [1]
	N'-[[5-(4-Ethoxyphenyl)-1H-pyrazol-4-yl]methyl]-N,N'-dimethylethane-1,2-diamine	IC50	28.0 [1]
	2-[4-[4-[[Methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-5-yl]phenoxy]butan-1-ol	IC50	22.0 [1]
	3-Methyl-2-[4-[4-[[methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-5-yl]phenoxy]butan-1-ol	IC50	55.0 [1]
	N'-[[4-[3-Chloro-4-propan-2-yloxy-5-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl]methyl]-N'-methylethane-1,2-diamine	IC50	70.0 [1]
	4-Methyl-2-[3-[4-[[methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-5-yl]-5-(trifluoromethyl)phenoxy]pentan-1-ol	IC50	44.0 [1]
	2-[4-[(3-Fluorophenyl)methoxy]piperidin-1-yl]-N-methylethanamine	IC50	1850.0 [1]
	N-Methyl-2-[4-[(3-phenylphenyl)methoxy]piperidin-1-yl]ethanamine	IC50	573.0 [1]
	N'-[[2-(2-Chlorophenyl)sulfanylphenyl]methyl]-N'-methylethane-1,2-diamine	IC50	1.1 [1]
	2-(4-Benzylpiperidin-1-yl)ethanamine	IC50	2100.0 [1]
	N-Methyl-2-(4-methylpiperidin-1-yl)ethanamine	IC50	15000.0 [1]
	(2R)-2-Amino-N-ethylpropanamide	IC50	200000.0 [1]
	N'-Methyl-N'-[[5-(4-propan-2-yloxyphenyl)-1H-pyrazol-4-yl]methyl]ethane-1,2-diamine	IC50	10.0 [1]
	N-{[5-(4-Fluorophenyl)-1h-Pyrazol-4-Yl]methyl}-N-Methylethane-1,2-Diamine	IC50	67.0 [1]
	(2Z)-3-(3-Phenylpropyl)-2-[(E)-3-[3-(3-phenylpropyl)benzo[g][1,3]benzothiazol-3-ium-2-yl]prop-2-enylidene]benzo[g][1,3]benzothiazole	IC50	28400.0 [1]
	(2E)-5-Bromo-2-[(2Z,4E)-3-bromo-5-(5-bromo-1-butyl-3,3-dimethylindol-1-ium-2-yl)penta-2,4-dienylidene]-1-butyl-3,3-dimethylindole	IC50	84900.0 [1]
	N-[(3-Bromophenyl)methyl]-1-[2-(methylamino)ethyl]piperidin-4-amine	IC50	9200.0 [1]
	N-Benzyl-1-[2-(methylamino)ethyl]piperidin-4-amine	IC50	50000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 36 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Protein arginine N-methyltransferase 8 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Dec. 2024, https://www.aatbio.com/data-sets/protein-arginine-n-methyltransferase-8-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 22). Quest Database™ Protein arginine N-methyltransferase 8 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-arginine-n-methyltransferase-8-inhibitors-ic50-ki.
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