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Protein arginine N-methyltransferase 6 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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4-Methyl-2-[3-[4-[[methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-5-yl]-5-(trifluoromethyl)phenoxy]pentan-1-olIC501900.0 [1], 20000.0 [2]
2-(4-Benzylpiperidin-1-yl)ethanamineIC50230.0 [1], 390.0 [2]
SulfathiazoleIC50430000.0 [1]
StilbamidineIC50173000.0 [1]
FuramidineIC50283000.0 [1]
N,N,N'-TrimethylethylenediamineIC505000.0 [1]
C.I. Direct Red 23IC5039200.0 [1]
CID 91668547IC5010.0 [1]
5-[5-(4-Carbamimidoylphenyl)furan-2-yl]pyridine-2-carboximidamideIC50211000.0 [1]
2-(2-Aminoethylthiomethyl)-5-dimethylaminomethylfuranIC5072000.0 [1]
{4-[(4-Methyl-1,4-diazepan-1-yl)methyl]phenyl}methanamineIC5024000.0 [1]
CID 53868701IC5043.0 [1]
N-Methyl-N-(3-pyridin-3-ylbenzyl)amineIC50104000.0 [1]
MS023IC504.0 [1]
PRMT5 Inhibitor C17IC50100000.0 [1]
N,N'-Dimethyl-N'-[[5-[3-(2-phenylethoxy)-5-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]methyl]ethane-1,2-diamineIC50327.0 [1]
N'-[[5-[3-(2-Cyclohexylethoxy)-5-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]methyl]-N,N'-dimethylethane-1,2-diamineIC50461.0 [1]
N,N'-Dimethyl-N'-[[5-(4-propan-2-yloxyphenyl)-1H-pyrazol-4-yl]methyl]ethane-1,2-diamineIC5011.0 [1]
N'-[[5-(3-Chloro-4-propan-2-yloxyphenyl)-1-methylpyrazol-4-yl]methyl]-N,N'-dimethylethane-1,2-diamineIC5023.0 [1]
N'-Methyl-N'-[[5-[4-(2-methylpropyl)phenyl]-1H-pyrazol-4-yl]methyl]ethane-1,2-diamineIC5010.0 [1]
N'-[[5-(3-Chloro-4-propan-2-yloxyphenyl)-1H-pyrazol-4-yl]methyl]-N'-methylethane-1,2-diamineIC508.0 [1]
N'-Methyl-N'-[[5-[4-(3-morpholin-4-ylpropoxy)phenyl]-1H-pyrazol-4-yl]methyl]ethane-1,2-diamineIC5013.0 [1]
N'-Methyl-N'-[[5-(4-phenoxyphenyl)-1H-pyrazol-4-yl]methyl]ethane-1,2-diamineIC502.0 [1]
1-[4-[4-[4-[[2-Aminoethyl(methyl)amino]methyl]-1H-pyrazol-5-yl]phenyl]piperazin-1-yl]-2-phenylethanoneIC5020.0 [1]
N'-[[5-(3-Chloro-4-propan-2-yloxyphenyl)-1H-pyrazol-4-yl]methyl]-N,N'-dimethylethane-1,2-diamineIC5010.0 [1]
N-Methyl-2-[4-[5-[[methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-4-yl]phenoxy]benzamideIC505.0 [1]
N,N-Dimethyl-3-[4-[4-[[methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-5-yl]phenoxy]benzamideIC503.0 [1]
N,N-Dimethyl-3-[4-[5-[[methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-4-yl]phenoxy]benzamideIC502.0 [1]
N'-[[5-(4-Ethoxyphenyl)-1H-pyrazol-4-yl]methyl]-N,N'-dimethylethane-1,2-diamineIC5025.0 [1]
2-[4-[4-[[Methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-5-yl]phenoxy]butan-1-olIC5025.0 [1]
3-Methyl-2-[4-[4-[[methyl-[2-(methylamino)ethyl]amino]methyl]-1H-pyrazol-5-yl]phenoxy]butan-1-olIC5032.0 [1]
N'-[[4-[3-Chloro-4-propan-2-yloxy-5-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl]methyl]-N'-methylethane-1,2-diamineIC50320.0 [1]
4-[[6-(4-Cyanoanilino)-5-nitropyrimidin-4-yl]amino]benzenecarboximidamideIC50100000.0 [1]
N-Methyl-2-(4-phenoxypiperidin-1-yl)ethanamineIC5090.0 [1]
N-Methyl-2-(4-phenylsulfanylpiperidin-1-yl)ethanamineIC50488.0 [1]
[1-[2-(Methylamino)ethyl]piperidin-4-yl] benzoateIC50107.0 [1]
N-Methyl-2-[4-[[4-(2-methylbutan-2-yl)phenyl]methoxy]piperidin-1-yl]ethanamineIC5067.0 [1]
2-[4-[(2-Bromophenyl)methoxy]piperidin-1-yl]-N-methylethanamineIC5025.0 [1]
1-[2-(Methylamino)ethyl]-N-phenylpiperidine-4-carboxamideIC505360.0 [1]
N-Methyl-2-[4-[[4-(2-methylpropyl)phenyl]methoxy]piperidin-1-yl]ethanamineIC5072.0 [1]
N-Methyl-2-[4-(2-phenylethyl)piperidin-1-yl]ethanamineIC5056.0 [1]
N-Methyl-2-[4-[[4-(trifluoromethyl)phenyl]methoxy]piperidin-1-yl]ethanamineIC50144.0 [1]
N-Methyl-2-[4-[[4-(trifluoromethoxy)phenyl]methoxy]piperidin-1-yl]ethanamineIC5046.0 [1]
N-Methyl-2-[4-[[4-(2,2,2-trifluoroethoxy)phenyl]methoxy]piperidin-1-yl]ethanamineIC5048.0 [1]
2-[4-[(2-Fluorophenyl)methoxy]piperidin-1-yl]-N-methylethanamineIC5047.0 [1]
2-(3-Benzylpiperidin-1-yl)-N-methylethanamineIC50290.0 [1]
2-[4-[(4-Fluorophenyl)methoxy]piperidin-1-yl]-N-methylethanamineIC5038.0 [1]
1-[2-(Methylamino)ethyl]-N-phenylpiperidin-4-amineIC50186.0 [1]
N-Methyl-2-[4-[[2-(trifluoromethyl)phenyl]methoxy]piperidin-1-yl]ethanamineIC5064.0 [1]
2-[4-[(3-Chlorophenyl)methoxy]piperidin-1-yl]-N-methylethanamineIC5078.0 [1]
2-[4-[(2-Chlorophenyl)methoxy]piperidin-1-yl]-N-methylethanamineIC5030.0 [1]
2-[4-[(3-Fluorophenyl)methoxy]piperidin-1-yl]-N-methylethanamineIC5056.0 [1]
2-[4-[[4-(3,5-Dimethylpyrazol-1-yl)phenyl]methoxy]piperidin-1-yl]-N-methylethanamineIC5025.0 [1]
2-[4-[(4-Chlorophenyl)methoxy]piperidin-1-yl]-N-methylethanamineIC5040.0 [1]
N-Methyl-2-[4-[(2-phenylphenyl)methoxy]piperidin-1-yl]ethanamineIC5048.0 [1]
2-[4-[(4-Bromophenyl)methoxy]piperidin-1-yl]-N-methylethanamineIC5044.0 [1]
2-[4-[(4-Cyclohexylphenyl)methoxy]piperidin-1-yl]-N-methylethanamineIC5028.0 [1]
N-[[1-[2-(Methylamino)ethyl]piperidin-4-yl]methyl]anilineIC50116.0 [1]
[1-[2-(Methylamino)ethyl]piperidin-4-yl]methyl benzoateIC50515.0 [1]
N-Methyl-2-[4-[(3-phenylphenyl)methoxy]piperidin-1-yl]ethanamineIC5030.0 [1]
N-[1-[2-(Methylamino)ethyl]piperidin-4-yl]benzamideIC50129.0 [1]
N-Methyl-2-[4-[(4-phenylphenyl)methoxy]piperidin-1-yl]ethanamineIC5027.0 [1]
N-Methyl-2-[4-[[3-(trifluoromethyl)phenyl]methoxy]piperidin-1-yl]ethanamineIC50117.0 [1]
2-[4-[[4-(2,3-Dichlorophenoxy)phenyl]methoxy]piperidin-1-yl]-N-methylethanamineIC5026.0 [1]
2-[4-[(3-Bromophenyl)methoxy]piperidin-1-yl]-N-methylethanamineIC5053.0 [1]
N'-[[2-(2-Chlorophenyl)sulfanylphenyl]methyl]-N'-methylethane-1,2-diamineIC501.2 [1]
[1-[2-(Methylamino)ethyl]piperidin-4-yl]-phenylmethanolIC50469.0 [1]
N-Methyl-N-(3-thien-2-ylbenzyl)amineIC50125000.0 [1]
N-[3-(2-Furyl)benzyl]-N-methylamineIC50146000.0 [1]
N-Methyl-N-(3-thien-3-ylbenzyl)amineIC5069000.0 [1]
4-Methyl-5-(3-(trifluoromethyl)-1H-pyrazol-1-yl)thiazol-2-amineIC5046000.0 [1]
N-Methyl-2-[4-(phenoxymethyl)piperidin-1-yl]ethanamineIC5092.0 [1]
2-(4-Benzylpiperidin-1-yl)-N-methylethanamineIC50170.0 [1]
1-(4-Benzylpiperidin-1-yl)-3-(methylamino)propan-2-olIC503040.0 [1]
N-Methyl-2-(4-methylpiperidin-1-yl)ethanamineIC502100.0 [1]
3-Pyrrolidin-1-ylmethyl-benzylamineIC50360000.0 [1]
2-(4-Benzylpiperidin-1-yl)-N-ethylethanamineIC50830.0 [1]
3-(4-Benzylpiperidin-1-yl)-N-methylpropan-1-amineIC5010000.0 [1]
N-Methyl-2-(4-phenylpiperidin-1-yl)ethanamineIC509340.0 [1]
2-(3-Benzylpyrrolidin-1-yl)-N-methylethanamineIC5070.0 [1]
N-Methyl-N-[3-(2-methyl-1,3-thiazol-4-YL)benzyl]amineIC50136000.0 [1]
N-Methyl(3-(pyridin-4-yl)phenyl)methanamineIC50100000.0 [1]
(2Z)-1-Ethyl-2-[(E)-3-(1-ethylbenzo[cd]indol-1-ium-2-yl)prop-2-enylidene]benzo[cd]indole;iodideIC5012600.0 [1]
(2R)-2-Amino-N-ethylpropanamideIC50200000.0 [1]
N-Methyl-N-(3-piperidin-1-ylbenzyl)amineIC50170000.0 [1]
N'-Methyl-N'-[[5-(4-propan-2-yloxyphenyl)-1H-pyrazol-4-yl]methyl]ethane-1,2-diamineIC507.0 [1]
N-{[5-(4-Fluorophenyl)-1h-Pyrazol-4-Yl]methyl}-N-Methylethane-1,2-DiamineIC5011.0 [1]
N-Methyl-1-(5-methylthiophen-2-yl)methanamineIC5099000.0 [1]
1-[2-(Methylamino)ethyl]-N-[(3-phenylphenyl)methyl]azetidin-3-amineIC5067.0 [1]
N-[(3-Bromophenyl)methyl]-1-[2-(methylamino)ethyl]piperidin-4-amineIC502160.0 [1]
1-[2-(Methylamino)ethyl]-N-[[3-(trifluoromethyl)phenyl]methyl]azetidin-3-amineIC50469.0 [1]
N-[(3-Fluorophenyl)methyl]-1-[2-(methylamino)ethyl]piperidin-4-amineIC501890.0 [1]
N-[(3-Fluorophenyl)methyl]-1-[2-(methylamino)ethyl]azetidin-3-amineIC50101.0 [1]
1-[2-(Methylamino)ethyl]-N-[[3-(trifluoromethoxy)phenyl]methyl]azetidin-3-amineIC50434.0 [1]
1-[2-(Methylamino)ethyl]-N-[[3-(trifluoromethyl)phenyl]methyl]piperidin-4-amineIC502980.0 [1]
N-[(3-Bromophenyl)methyl]-1-[2-(methylamino)ethyl]azetidin-3-amineIC50249.0 [1]
1-[2-(Methylamino)ethyl]-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidin-4-amineIC504730.0 [1]
1-[2-(Methylamino)ethyl]-N-[(3-phenylphenyl)methyl]piperidin-4-amineIC50120.0 [1]
N-[(3-Chlorophenyl)methyl]-1-[2-(methylamino)ethyl]piperidin-4-amineIC502920.0 [1]
N-Methyl-2-[3-[[3-(trifluoromethoxy)phenyl]methoxy]azetidin-1-yl]ethanamineIC501079.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Protein arginine N-methyltransferase 6 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/protein-arginine-n-methyltransferase-6-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Protein arginine N-methyltransferase 6 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-arginine-n-methyltransferase-6-inhibitors-ic50-ki.
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