Protein arginine N-methyltransferase 5 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Stilbamidine	IC50	44100.0 [1], 712000.0 [2]
	Furamidine	IC50	166000.0 [1], 256000.0 [2]
	S-Adenosyl-L-homocysteine	IC50	50000.0 [1]
	Pentamidine	IC50	582000.0 [1]
	Hexamidine	IC50	357000.0 [1]
	CID 71268957	IC50	100000.0 [1]
	CID 90241673	IC50	22.0 [1]
	Bromo-deaza-SAH	IC50	2300.0 [1]
	6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine	IC50	100000.0 [1]
	({[5-(4-Chlorophenyl)furan-2-yl]methylidene}amino)urea	IC50	570.0 [1]
	5-[5-(4-Carbamimidoylphenyl)furan-2-yl]pyridine-2-carboximidamide	IC50	186000.0 [1]
	(1S,2R,3S,5R)-3-[2-(2-Amino-3-bromoquinolin-7-yl)ethyl]-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol	IC50	6.3 [1]
	N-[(9-Ethyl-9H-carbazol-3-yl)methyl]-1,2,3,4-tetrahydronaphthalen-1-amine	IC50	517.0 [1]
	(2E)-2-[(E)-3-[1,1-Dimethyl-3-(3-phenylpropyl)benzo[e]indol-3-ium-2-yl]prop-2-enylidene]-1,1-dimethyl-3-(3-phenylpropyl)benzo[e]indole;bromide	IC50	1400.0 [1]
	1-[2-[[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]ethyl]-3-ethylurea	IC50	50000.0 [1]
	4-[[6-(4-Cyanoanilino)-5-nitropyrimidin-4-yl]amino]benzenecarboximidamide	IC50	100000.0 [1]
	2-(1-Acetylpiperidin-4-yl)oxy-3-chloro-N-[(2R)-2-hydroxy-2-[(3S)-1,2,3,4-tetrahydroisoquinolin-3-yl]ethyl]pyridine-4-carboxamide	IC50	26.0 [1]
	N'-[[2-(2-Chlorophenyl)sulfanylphenyl]methyl]-N'-methylethane-1,2-diamine	IC50	100000.0 [1]
	2-(1-Acetylpiperidin-4-yl)oxy-3-chloro-N-[(2S)-3-(2,3-dihydro-1H-inden-2-ylamino)-2-hydroxypropyl]pyridine-4-carboxamide	IC50	105.0 [1]
	N-[(6-Methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide	IC50	100000.0 [1]
	N-[(4,6-Dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide	IC50	100000.0 [1]
	(2Z)-1-Ethyl-2-[(E)-3-(1-ethylbenzo[cd]indol-1-ium-2-yl)prop-2-enylidene]benzo[cd]indole;iodide	IC50	9100.0 [1]
	4-[10-(4-Carbamimidoylphenoxy)decoxy]benzenecarboximidamide	IC50	43000.0 [1]
	N-[(2S)-2-Hydroxy-3-piperidin-1-ylpropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide	IC50	10000.0 [1]
	N-[(2S)-3-(3,4-Dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-(morpholine-4-carbonyl)benzamide	IC50	109.0 [1]
	(2Z)-5-Bromo-2-[(E)-3-(5-bromo-3-butyl-1,3-benzothiazol-3-ium-2-yl)prop-2-enylidene]-3-butyl-1,3-benzothiazole	IC50	8360.0 [1]
	(2Z)-3-(3-Phenylpropyl)-2-[(E)-3-[3-(3-phenylpropyl)benzo[g][1,3]benzothiazol-3-ium-2-yl]prop-2-enylidene]benzo[g][1,3]benzothiazole	IC50	7040.0 [1]
	(2E)-5-Bromo-2-[(2Z,4E)-3-bromo-5-(5-bromo-1-butyl-3,3-dimethylindol-1-ium-2-yl)penta-2,4-dienylidene]-1-butyl-3,3-dimethylindole	IC50	35400.0 [1]
	N-[(3-Bromophenyl)methyl]-1-[2-(methylamino)ethyl]piperidin-4-amine	IC50	50000.0 [1]
	N-Benzyl-1-[2-(methylamino)ethyl]piperidin-4-amine	IC50	50000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 30 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Protein arginine N-methyltransferase 5 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/protein-arginine-n-methyltransferase-5-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 22). Quest Database™ Protein arginine N-methyltransferase 5 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-arginine-n-methyltransferase-5-inhibitors-ic50-ki.
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