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Prostaglandin I2 synthase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
DazoxibenIC50100000.0 [1]
3-Isopropyl-3-(1-imidazolylmethyl)indoleIC50100000.0 [1], 1000000.0 [2]
ImidazoleIC504000000.0 [1]
DazmegrelIC50100000.0 [1]
PirmagrelIC50100000.0 [1]
IsbogrelIC50100000.0 [1]
3-Imidazol-1-ylmethyl-1H-indoleIC50650000.0 [1]
N-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamideIC50100000.0 [1]
1-(2-Phenoxy-ethyl)-1H-imidazoleIC501000000.0 [1]
3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-acrylic acidIC50100000.0 [1]
2-(2-Imidazol-1-yl-ethoxy)-benzoic acid ethyl esterIC50100000.0 [1]
4-(2-Imidazol-1-yl-ethoxy)-benzamideIC50100000.0 [1]
[4-(2-Imidazol-1-yl-ethoxy)-phenyl]-acetic acid ethyl esterIC501000000.0 [1]
N-[4-(2-Imidazol-1-yl-ethoxy)-phenyl]-acetamideIC501000000.0 [1]
[2-(2-Imidazol-1-yl-ethoxy)-phenyl]-acetic acidIC50100000.0 [1]
[4-(2-Imidazol-1-yl-ethoxy)-phenoxy]-acetic acidIC50100000.0 [1]
3-(2-Imidazol-1-yl-ethoxy)-benzoic acidIC50100000.0 [1]
4-(2-Imidazol-1-yl-ethoxy)-N-methyl-benzamideIC50100000.0 [1]
4-(2-Imidazol-1-yl-ethoxy)-N,N-dimethyl-benzamideIC50100000.0 [1]
2H-Tetrazole, 5-[4-[2-(1H-imidazol-1-yl)ethoxy]phenyl]-IC501000000.0 [1]
(3-Imidazol-1-ylmethyl-indol-1-yl)-acetic acidIC50100000.0 [1]
3-[3-(Imidazol-1-ylmethyl)indol-1-yl]propanoic acidIC50100000.0 [1]
3-(3-Imidazol-1-ylmethyl-2-isopropyl-indol-1-yl)-propionic acidIC50100000.0 [1]
3-(3-Imidazol-1-ylmethyl-5-methyl-indol-1-yl)-propionic acidIC50100000.0 [1]
3-(3-Imidazol-1-ylmethyl-5-methoxy-indol-1-yl)-propionic acidIC50100000.0 [1]
3-(5-Chloro-3-imidazol-1-ylmethyl-indol-1-yl)-propionic acidIC50100000.0 [1]
3-(5-Bromo-3-imidazol-1-ylmethyl-indol-1-yl)-propionic acidIC50100000.0 [1]
3-(5-Dimethylamino-3-imidazol-1-ylmethyl-indol-1-yl)-propionic acidIC50100000.0 [1]
3-(3-Imidazol-1-ylmethyl-6-trifluoromethyl-indol-1-yl)-propionic acidIC50100000.0 [1]
2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carboxylic acidIC5010.0 [1]
3-Chloro-2-imidazol-1-ylmethyl-benzofuran-5-carboxylic acidIC50100000.0 [1]
2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxylic acidIC50100000.0 [1]
2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5-carboxylic acidIC50100000.0 [1]
2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-6-carboxylic acidIC50100000.0 [1]
3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-6-carboxylic acidIC50100000.0 [1]
(Z)-6-[2-(1-Methyl-1-phenoxy-ethyl)-4-pyridin-3-yl-[1,3]dioxan-5-yl]-hex-4-enoic acidIC5075000.0 [1]
(Z)-6-[2-(4-Cyano-phenyl)-4-pyridin-3-yl-[1,3]dioxan-5-yl]-hex-4-enoic acidIC50100000.0 [1]
CID 44209343IC501000.0 [1]
(Z)-6-[2-[2-(4-Methyl-2-nitrophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5028000.0 [1]
(Z)-6-[2-[2-(2-Hydroxyphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC50100000.0 [1]
(Z)-6-[2-[2-(2-Cyano-4-methylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5047000.0 [1]
3-(2-Cyclopropyl-3-imidazol-1-ylmethyl-indol-1-yl)-propionic acidIC50100000.0 [1]
(Z)-6-[2-[2-(2-Cyano-4-fluorophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5037000.0 [1]
(Z)-6-[2-(3,4-Dichlorophenyl)-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC509000.0 [1]
(Z)-6-[2-[2-(2-Cyano-6-methylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5060000.0 [1]
(Z)-6-[2-[2-(4-Fluoro-2-nitrophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC509000.0 [1]
(Z)-6-[2-[2-(4-Methylsulfanylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5032000.0 [1]
(Z)-6-[2-[2-(4-Cyanophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC504000.0 [1]
(Z)-6-[2-[2-(4-Methoxyphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC50100000.0 [1]
(Z)-6-[2-[2-(2-Methylsulfonylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC502000.0 [1]
(Z)-6-[2-[1-(4-Fluorophenyl)-2-methylpropan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC502000.0 [1]
(Z)-6-[2-[2-(2-Cyanophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC503000.0 [1]
(Z)-6-[2-[2-(2-Nitrophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC501000.0 [1]
(Z)-6-[2-[1-(2-Cyano-4-fluorophenyl)-2-methylpropan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC507000.0 [1]
(Z)-6-[2-[1-(2-Cyanophenyl)-2-methylpropan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5014000.0 [1]
(Z)-6-[2-(2-Methyl-1-phenylpropan-2-yl)-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5013000.0 [1]
(Z)-6-[2-[2-(2-Bromophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC507000.0 [1]
(Z)-6-[2-[2-(4-Methylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5025000.0 [1]
(Z)-6-[2-(2,4-Dichlorophenyl)-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC502500.0 [1]
(Z)-6-[2-[2-(4-Fluorophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC502000.0 [1]
(Z)-6-[2-[2-(4-Methylsulfonylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC508000.0 [1]
(Z)-6-[2-(2-Cyanophenyl)-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC50100000.0 [1]
(Z)-6-[2-(4-Nitrophenyl)-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5013000.0 [1]
(Z)-6-[2-[2-(4-Methoxy-2-nitrophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5023000.0 [1]
(Z)-6-[2-[2-(2-Methoxycarbonylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5073000.0 [1]
(Z)-6-[2-[2-(2-Cyano-5-methylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC50100000.0 [1]
(Z)-6-[2-[2-(4-Acetyl-2-nitrophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC504000.0 [1]
(Z)-6-[2-[2-(4-Methylsulfanyl-2-nitrophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC505000.0 [1]
(Z)-6-[2-[2-(2-Methylsulfanylphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC50100000.0 [1]
(Z)-6-[2-[2-(2-Methoxyphenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5051000.0 [1]
(Z)-6-[2-[2-(2-Fluorophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC501000.0 [1]
(Z)-6-[2-[2-(3-Fluorophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acidIC5040000.0 [1]
Items per page: 1 - 10 of 72
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References

This online tool may be cited as follows

MLA

"Quest Database™ Prostaglandin I2 synthase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/prostaglandin-i2-synthase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Prostaglandin I2 synthase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/prostaglandin-i2-synthase-inhibitors-ic50-ki.
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