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Prostaglandin E synthase 2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
CID 11526708IC503.0 [1], 1000.0 [2]
3-(1-(4-Chlorobenzyl)-5-(2-fluorobiphenyl-4-yl)-3-methyl-1H-indol-2-yl)-2,2-dimethylpropanoic acidIC507.0 [1], 1000.0 [2]
2-(9-Chloro-1h-Phenanthro[9,10-D]imidazol-2-Yl)benzene-1,3-DicarbonitrileIC5030000.0 [1]
3-(3-(Tert-butylthio)-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl)-2,2-dimethylpropanoic acidIC501600.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-5-fluoro-3-methyl-2-indolyl]-2,2-dimethylpropanoic acidIC502600.0 [1]
CID 16730275IC5030000.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-3-methyl-5-(4-phenylphenyl)indol-2-yl]-2,2-dimethylpropanoic acidIC5016.0 [1]
3-[5-[4-(2-Chlorophenyl)-3-fluorophenyl]-1-[(4-chlorophenyl)methyl]-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC504.0 [1]
2-(6-Chloro-9-(3-hydroxy-3-methylbut-1-ynyl)-1H-phenanthro[9,10-d]imidazol-2-yl)isophthalonitrileIC5030000.0 [1]
3-(3-Tert-butylsulfanyl-5-propan-2-yl-1-prop-2-enylindol-2-yl)-2,2-dimethylpropanoic acidIC506700.0 [1]
Methyl 3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoateIC507200.0 [1]
3-[3-Tert-butylsulfanyl-1-(3-phenylpropyl)-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acidIC503200.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-3-(2-methylbenzoyl)-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acidIC50900.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-3-(3,3-dimethylbutanoyl)-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acidIC50250.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-5-(3-chloro-4-phenylphenyl)-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC5022.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-5-[3-fluoro-4-(2-methoxyphenyl)phenyl]-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC505.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-5-(3-fluoro-4-pyridin-3-ylphenyl)-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC5012.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-5-[3-fluoro-4-(2-fluorophenyl)phenyl]-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC508.0 [1]
3-[5-[4-(2-Acetylphenyl)-3-fluorophenyl]-1-[(4-chlorophenyl)methyl]-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC506.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-5-[3-fluoro-4-(3-methylphenyl)phenyl]-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC5033.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-5-[3-fluoro-4-(4-methylphenyl)phenyl]-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC5031.0 [1]
3-Nitro-4-[[4-(4-phenylphenyl)triazol-1-yl]methyl]benzoic acidIC503200.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC503200.0 [1]
3-(3-Tert-butylsulfanyl-5-propan-2-yl-1H-indol-2-yl)-2,2-dimethylpropanoic acidIC5010000.0 [1]
3-(3-Tert-butylsulfanyl-1-methyl-5-propan-2-ylindol-2-yl)-2,2-dimethylpropanoic acidIC5010000.0 [1]
Amino 3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoateIC5010000.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-3-phenyl-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acidIC506400.0 [1]
3-[3-[(4-Tert-butylphenyl)methyl]-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acidIC50290.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-3-phenoxy-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acidIC50650.0 [1]
3-[3-(2-Tert-butylsulfanylacetyl)-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acidIC50260.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-3-methyl-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acidIC501100.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-3-methyl-7-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acidIC504300.0 [1]
3-[5-Tert-butyl-1-[(4-chlorophenyl)methyl]-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC50330.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-3-methyl-5-phenylindol-2-yl]-2,2-dimethylpropanoic acidIC50600.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-3-methyl-5-(3-phenylphenyl)indol-2-yl]-2,2-dimethylpropanoic acidIC50160.0 [1]
3-[1-[(4-Chlorophenyl)methyl]-5-(3-fluoro-4-pyrazin-2-ylphenyl)-3-methylindol-2-yl]-2,2-dimethylpropanoic acidIC5032.0 [1]
4-[4-[1-(Phenylsulfanylmethyl)triazol-4-yl]phenyl]phenolIC5030000.0 [1]
3-[4-[1-(Phenylsulfanylmethyl)triazol-4-yl]phenyl]phenolIC5030000.0 [1]
4-(4-Phenanthren-9-ylphenyl)-1-(3-phenylpropyl)triazoleIC5030000.0 [1]
[1-(Phenylsulfanylmethyl)triazol-4-yl]methyl benzoateIC5030000.0 [1]
4-[4-[1-(3-Phenylpropyl)triazol-4-yl]phenyl]phenolIC5030000.0 [1]
4-[4-[2-(Naphthalen-1-yloxymethyl)phenyl]phenyl]-1-(3-phenylpropyl)triazoleIC5030000.0 [1]
4-[4-[2-[[2-Chloro-5-(trifluoromethyl)phenoxy]methyl]phenyl]phenyl]-1-(3-phenylpropyl)triazoleIC5030000.0 [1]
4-[4-[2-[[2-Chloro-5-(trifluoromethyl)phenoxy]methyl]phenyl]phenyl]-1-[2-(2-methylphenyl)ethyl]triazoleIC5030000.0 [1]
4-[4-[4-[2-(Naphthalen-1-yloxymethyl)phenyl]phenyl]triazol-1-yl]sulfonylbenzoic acidIC5030000.0 [1]
5-(Dimethylamino)-N-[4-[4-[1-(3-phenylpropyl)triazol-4-yl]phenyl]phenyl]naphthalene-1-sulfonamideIC5030000.0 [1]
1-[2-(2-Methylphenyl)ethyl]-4-[4-[2-(naphthalen-1-yloxymethyl)phenyl]phenyl]triazoleIC5030000.0 [1]
4-[4-[1-[2-(2-Methylphenyl)ethyl]triazol-4-yl]phenyl]anilineIC5030000.0 [1]
4-[4-(4-Phenoxyphenyl)phenyl]-1-(3-phenylpropyl)triazoleIC5030000.0 [1]
4-[5-Benzyl-3-(phenylsulfanylmethyl)triazol-4-yl]benzaldehydeIC5030000.0 [1]
2-[[3-(5-Chloro-6-methoxypyridin-3-yl)phenyl]sulfonylamino]benzenesulfonamideIC5022.0 [1]
2-[[(E)-2-(3-Chlorophenyl)ethenyl]sulfonylamino]-5-methylbenzenesulfonamideIC503000.0 [1]
2-[[(E)-2-(3-Chlorophenyl)ethenyl]sulfonylamino]-3-fluorobenzenesulfonamideIC503100.0 [1]
3-Fluoro-2-[[(E)-2-[3-(trifluoromethyl)phenyl]ethenyl]sulfonylamino]benzenesulfonamideIC503800.0 [1]
2-Fluoro-6-[[(E)-2-[3-(trifluoromethyl)phenyl]ethenyl]sulfonylamino]benzenesulfonamideIC506200.0 [1]
4-Fluoro-2-[[(E)-2-(2-fluorophenyl)ethenyl]sulfonylamino]benzenesulfonamideIC506400.0 [1]
5-Methyl-2-[[(E)-2-[3-(trifluoromethyl)phenyl]ethenyl]sulfonylamino]benzenesulfonamideIC509100.0 [1]
2-[2-(4-Cyclopentylphenyl)ethylsulfonylamino]benzenesulfonamideIC50270.0 [1]
2-[2-(4-Tert-butylphenyl)ethylsulfonylamino]benzenesulfonamideIC50220.0 [1]
2-[2-(4-Tert-butylphenyl)ethylsulfonylamino]-4-fluorobenzenesulfonamideIC50300.0 [1]
2-[2-(4-Chlorophenyl)ethylsulfonylamino]benzenesulfonamideIC50490.0 [1]
2-[[(E)-2-(4-Chlorophenyl)ethenyl]sulfonylamino]benzenesulfonamideIC50290.0 [1]
2-(Phenethylsulfonylamino)benzenesulfonamideIC509800.0 [1]
2-[[(E)-2-Phenylethenyl]sulfonylamino]benzenesulfonamideIC502600.0 [1]
2-[2-(2-Chlorophenyl)ethylsulfonylamino]benzenesulfonamideIC501200.0 [1]
2-[[(E)-2-(4-Methoxyphenyl)ethenyl]sulfonylamino]benzenesulfonamideIC503100.0 [1]
2-[[(E)-2-(4-Chlorophenyl)ethenyl]sulfonylamino]-4-fluoro-benzenesulfonamideIC50350.0 [1]
2-(2-Phenylpropylsulfonylamino)benzenesulfonamideIC509900.0 [1]
2-[[(E)-2-(4-Chlorophenyl)ethenyl]sulfonylamino]-6-fluorobenzenesulfonamideIC50570.0 [1]
2-[[(E)-2-(2,6-Dichlorophenyl)ethenyl]sulfonylamino]benzenesulfonamideIC502900.0 [1]
2-[[(E)-2-(4-Methylphenyl)ethenyl]sulfonylamino]benzenesulfonamideIC507300.0 [1]
2-[[(E)-2-(2-Methoxyphenyl)ethenyl]sulfonylamino]benzenesulfonamideIC50430.0 [1]
2-[[(E)-2-Naphthalen-2-ylethenyl]sulfonylamino]benzenesulfonamideIC50190.0 [1]
2-[2-(4-Chlorophenyl)ethylsulfonylamino]-4-fluoro-benzenesulfonamideIC50800.0 [1]
2-[[(E)-2-(4-Chlorophenyl)prop-1-enyl]sulfonylamino]benzenesulfonamideIC50700.0 [1]
2-[2-(4-Chlorophenyl)prop-2-enylsulfonylamino]benzenesulfonamideIC502400.0 [1]
2-Fluoro-6-[[(E)-2-naphthalen-2-ylethenyl]sulfonylamino]benzenesulfonamideIC501300.0 [1]
2-Fluoro-6-[[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]sulfonylamino]benzenesulfonamideIC50870.0 [1]
2-[[(E)-2-(4-Bromophenyl)ethenyl]sulfonylamino]-6-fluorobenzenesulfonamideIC50310.0 [1]
4-Fluoro-2-[[(E)-2-naphthalen-2-ylethenyl]sulfonylamino]benzenesulfonamideIC5091.0 [1]
4-Fluoro-2-[[(E)-2-[2-(trifluoromethyl)phenyl]ethenyl]sulfonylamino]benzenesulfonamideIC50650.0 [1]
4-Fluoro-2-[[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]sulfonylamino]benzenesulfonamideIC50650.0 [1]
2-[[(E)-2-(4-Bromophenyl)ethenyl]sulfonylamino]-4-fluorobenzenesulfonamideIC50310.0 [1]
2-[[(E)-2-(4-Bromophenyl)ethenyl]sulfonylamino]-5-methylbenzenesulfonamideIC50680.0 [1]
5-Fluoro-2-[[(E)-2-naphthalen-2-ylethenyl]sulfonylamino]benzenesulfonamideIC50290.0 [1]
2-[[(E)-2-(4-Bromophenyl)ethenyl]sulfonylamino]-5-fluorobenzenesulfonamideIC50850.0 [1]
2-[[(E)-2-(2,6-Difluorophenyl)ethenyl]sulfonylamino]benzenesulfonamideIC509200.0 [1]
2-[[(E)-2-[2-(Trifluoromethyl)phenyl]ethenyl]sulfonylamino]benzenesulfonamideIC504600.0 [1]
2-[[(E)-2-[4-(Trifluoromethyl)phenyl]ethenyl]sulfonylamino]benzenesulfonamideIC50670.0 [1]
[(E)-2-(4-Bromophenyl)ethenylsulfonylamino]benzenesulfonamideIC5074.0 [1]
2-[[(E)-2-[4-(1-Benzofuran-2-yl)phenyl]ethenyl]sulfonylamino]-5-fluorobenzenesulfonamideIC5079.0 [1]
2-[[(E)-2-[4-(1-Benzofuran-2-yl)phenyl]ethenyl]sulfonylamino]-4-fluorobenzenesulfonamideIC5040.0 [1]
2-[[(E)-2-[4-(1-Benzofuran-2-yl)phenyl]ethenyl]sulfonylamino]-6-fluorobenzenesulfonamideIC5074.0 [1]
2-[1-(4-Chlorophenyl)propan-2-ylsulfonylamino]benzenesulfonamideIC50280.0 [1]
2-(1-Phenylpropan-2-ylsulfonylamino)benzenesulfonamideIC502200.0 [1]
2-[[(E)-1-(4-Chlorophenyl)prop-1-en-2-yl]sulfonylamino]benzenesulfonamideIC50610.0 [1]
2-[1-(4-Chlorophenyl)propan-2-ylsulfonylamino]-4-fluoro-benzenesulfonamideIC50450.0 [1]
2-[[(E)-1-(4-Chlorophenyl)prop-1-en-2-yl]sulfonylamino]-4-fluoro-benzenesulfonamideIC50590.0 [1]
2-[[(E)-1-(4-Chlorophenyl)prop-1-en-2-yl]sulfonylamino]-5-fluorobenzenesulfonamideIC501000.0 [1]
2-[[(E)-1-(4-Chlorophenyl)prop-1-en-2-yl]sulfonylamino]-6-fluorobenzenesulfonamideIC50520.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Prostaglandin E synthase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/prostaglandin-e-synthase-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Prostaglandin E synthase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/prostaglandin-e-synthase-2-inhibitors-ic50-ki.
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