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Potassium-transporting ATPase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
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▼
OmeprazoleIC50370.0 [1]
CimetidineIC50820.0 [1], 100000.0 [2]
N-Butyl-N-[3-[4-(2-phenyl-1,3-thiazol-4-yl)phenoxy]propyl]butan-1-amine;hydrochlorideIC50420.0 [1], 450.0 [2]
N-Butyl-N-[3-[4-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]phenoxy]propyl]butan-1-amineIC501800.0 [1], 2100.0 [2]
N-Butyl-N-[2-[4-(2-phenyl-1,3-thiazol-4-yl)phenoxy]ethyl]butan-1-amine;hydrochlorideIC50310.0 [1], 350.0 [2]
N,N-Dibutyl-4-[4-(2-phenyl-1,3-thiazol-4-yl)phenoxy]butan-1-amine;hydrochlorideIC50120.0 [1], 130.0 [2]
2-Phenyl-4-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-1,3-thiazole;hydrochlorideIC50390.0 [1], 10000.0 [2]
2-Phenyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]-1,3-thiazole;hydrochlorideIC5050.0 [1], 110.0 [2]
4-[4-(3-Imidazol-1-ylpropoxy)phenyl]-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole;hydrochlorideIC50370.0 [1], 620.0 [2]
4-[4-(3-Imidazol-1-ylpropoxy)phenyl]-2-pyridin-3-yl-1,3-thiazole;hydrochlorideIC503000.0 [1], 3300.0 [2]
N-[3-[4-[(E)-2-(1,3-Benzoxazol-2-yl)ethenyl]phenoxy]propyl]-N-butylbutan-1-amine;hydrochlorideIC50150.0 [1]
N-Butyl-N-[3-[4-[(E)-2-(6-methoxy-1,3-benzoxazol-2-yl)ethenyl]phenoxy]propyl]butan-1-amine;hydrochlorideIC5050.0 [1], 80.0 [2]
3-[4-[(E)-2-(1,3-Benzoxazol-2-yl)ethenyl]phenoxy]-N,N-diethylpropan-1-amine;hydrochlorideIC50320.0 [1], 980.0 [2]
2-[(E)-2-[4-(4-Piperidin-1-ylbutoxy)phenyl]ethenyl]-1,3-benzoxazole;hydrochlorideIC50170.0 [1], 330.0 [2]
N-Butyl-N-[3-[4-[(E)-2-(5-chloro-1,3-benzothiazol-2-yl)ethenyl]phenoxy]propyl]butan-1-amineIC50400.0 [1], 500.0 [2]
N-[3-[4-[(E)-2-(1H-Benzimidazol-2-yl)ethenyl]phenoxy]propyl]-N-butylbutan-1-amineIC501500.0 [1], 2300.0 [2]
N-Butyl-N-[3-[4-[(E)-2-(1-methylbenzimidazol-2-yl)ethenyl]phenoxy]propyl]butan-1-amineIC50800.0 [1], 2600.0 [2]
2-[[Amino(amino)methylene]amino]-5-methyl-4-(2-methyl-1H-pyrrol-4-yl)thiazoleIC501000.0 [1], 1200.0 [2]
3-[4-[(E)-2-(1,3-Benzothiazol-2-yl)ethenyl]phenoxy]-N,N-dipropylpropan-1-amine;hydrate;hydrochlorideIC50140.0 [1], 210.0 [2]
2-[(E)-2-[4-(3-Imidazol-1-ylpropoxy)phenyl]ethenyl]-1,3-benzoxazole;hydrate;hydrochlorideIC50250.0 [1], 290.0 [2]
2-[(E)-2-[4-(5-Imidazol-1-ylpentoxy)phenyl]ethenyl]-1,3-benzoxazole;hydrate;hydrochlorideIC50230.0 [1], 280.0 [2]
2-[(E)-2-[4-(4-Pyrrolidin-1-ylbutoxy)phenyl]ethenyl]-1,3-benzothiazole;hydrate;hydrochlorideIC50160.0 [1], 260.0 [2]
N-[3-[4-(1,3-Benzothiazol-2-yl)phenoxy]propyl]-N-butylbutan-1-amine;hydrate;hydrochlorideIC50250.0 [1], 2600.0 [2]
N-[2-[4-[(E)-2-(1,3-Benzothiazol-2-yl)ethenyl]phenoxy]ethyl]-N-butylbutan-1-amine;hydrate;hydrochlorideIC50430.0 [1], 600.0 [2]
N-Butyl-N-[3-[4-[2-(4-methylphenyl)-1,3-thiazol-4-yl]phenoxy]propyl]butan-1-amine;hydrochlorideIC501500.0 [1], 3000.0 [2]
N-Butyl-N-[3-[4-[2-(4-methoxyphenyl)-1,3-thiazol-4-yl]phenoxy]propyl]butan-1-amine;hydrate;hydrochlorideIC50230.0 [1], 480.0 [2]
N-[3-[4-[(E)-2-(1,3-Benzothiazol-2-yl)ethenyl]phenoxy]propyl]-N-butylbutan-1-amine;hydrate;hydrochlorideIC50250.0 [1], 260.0 [2]
N-[2-[4-[(E)-2-(1,3-Benzoxazol-2-yl)ethenyl]phenoxy]ethyl]-N-butylbutan-1-amine;hydrochlorideIC50260.0 [1], 540.0 [2]
N-Butyl-N-[3-[4-[(E)-2-(5-methyl-1,3-benzothiazol-2-yl)ethenyl]phenoxy]propyl]butan-1-amine;hydrochlorideIC50290.0 [1], 530.0 [2]
N-Butyl-N-[3-[4-[(E)-2-(5-methyl-1,3-benzoxazol-2-yl)ethenyl]phenoxy]propyl]butan-1-amine;hydrochlorideIC50260.0 [1], 340.0 [2]
2-[(E)-2-[4-(4-Imidazol-1-ylbutoxy)phenyl]ethenyl]-1,3-benzoxazole;hydrate;hydrochlorideIC50270.0 [1], 330.0 [2]
4-[4-(4-Imidazol-1-ylbutoxy)phenyl]-2-phenyl-1,3-thiazole;hydrate;hydrochlorideIC50310.0 [1], 820.0 [2]
3-[4-[(E)-2-(1,3-Benzothiazol-2-yl)ethenyl]phenoxy]-N,N-diethylpropan-1-amine;hydrate;hydrochlorideIC50150.0 [1], 370.0 [2]
2-[(E)-2-[4-(3-Piperidin-1-ylpropoxy)phenyl]ethenyl]-1,3-benzothiazole;hydrate;hydrochlorideIC50180.0 [1], 210.0 [2]
3-[4-(1,3-Benzothiazol-2-yl)phenoxy]-N,N-dipropylpropan-1-amine;hydrate;hydrochlorideIC50140.0 [1], 210.0 [2]
N-[3-[4-(1H-Benzimidazol-2-yl)phenoxy]propyl]-N-butylbutan-1-amine;hydrate;hydrochlorideIC501200.0 [1], 1800.0 [2]
4-[4-[(E)-2-(1,3-Benzoxazol-2-yl)ethenyl]phenoxy]-N,N-dipropylbutan-1-amine;hydrochlorideIC50110.0 [1], 390.0 [2]
2-[(E)-2-[4-(3-Imidazol-1-ylpropoxy)phenyl]ethenyl]-1,3-benzothiazole;hydrochlorideIC50130.0 [1], 340.0 [2]
4-[4-[(E)-2-(1,3-Benzothiazol-2-yl)ethenyl]phenoxy]-N,N-diethylbutan-1-amine;hydrate;hydrochlorideIC50180.0 [1], 350.0 [2]
4-[4-[(E)-2-(1,3-Benzothiazol-2-yl)ethenyl]phenoxy]-N,N-dipropylbutan-1-amine;hydrate;hydrochlorideIC5030.0 [1], 120.0 [2]
N,N-Dibutyl-5-[4-(2-phenyl-1,3-thiazol-4-yl)phenoxy]pentan-1-amine;hydrate;hydrochlorideIC50490.0 [1], 860.0 [2]
2-[(E)-2-[4-(4-Imidazol-1-ylbutoxy)phenyl]ethenyl]-1,3-benzothiazole;hydrate;hydrochlorideIC50200.0 [1], 260.0 [2]
N,N-Diethyl-3-[4-(2-phenyl-1,3-thiazol-4-yl)phenoxy]propan-1-amine;hydrate;hydrochlorideIC5090.0 [1], 120.0 [2]
3-[4-(2-Phenyl-1,3-thiazol-4-yl)phenoxy]-N,N-dipropylpropan-1-amine;hydrate;hydrochlorideIC50180.0 [1], 230.0 [2]
N-Butyl-N-[3-[4-[(E)-2-(6-methoxy-1,3-benzothiazol-2-yl)ethenyl]phenoxy]propyl]butan-1-amine;hydrate;hydrochlorideIC50260.0 [1], 460.0 [2]
N-Butyl-N-[3-[4-[2-(3,5-dimethoxyphenyl)-1,3-thiazol-4-yl]phenoxy]propyl]butan-1-amine;hydrate;hydrochlorideIC50260.0 [1], 540.0 [2]
4-[4-(3-Imidazol-1-ylpropoxy)phenyl]-2-phenyl-1,3-thiazole;hydrate;hydrochlorideIC5020.0 [1], 80.0 [2]
N-Butyl-N-[3-[4-(5-methyl-2-phenyl-1,3-thiazol-4-yl)phenoxy]propyl]butan-1-amine;hydrate;hydrochlorideIC50230.0 [1], 270.0 [2]
N-Butyl-N-[3-[4-(2-methyl-1,3-thiazol-4-yl)phenoxy]propyl]butan-1-amine;hydrochlorideIC501500.0 [1], 8400.0 [2]
N-Butyl-N-[3-[4-(5-ethyl-2-phenyl-1,3-thiazol-4-yl)phenoxy]propyl]butan-1-amine;hydrate;hydrochlorideIC50240.0 [1], 340.0 [2]
N-Butyl-N-[3-[4-(2-pyridin-3-yl-1,3-thiazol-4-yl)phenoxy]propyl]butan-1-amine;hydrate;hydrochlorideIC50880.0 [1], 1650.0 [2]
3-[4-[(E)-2-(1,3-Benzoxazol-2-yl)ethenyl]phenoxy]-N,N-dipropylpropan-1-amine;hydrate;hydrochlorideIC50220.0 [1], 350.0 [2]
2-[(E)-2-[4-(4-Pyrrolidin-1-ylbutoxy)phenyl]ethenyl]-1,3-benzoxazole;hydrate;hydrochlorideIC50170.0 [1], 240.0 [2]
4-[4-[(E)-2-(1,3-Benzoxazol-2-yl)ethenyl]phenoxy]-N,N-dibutylbutan-1-amine;hydrate;hydrochlorideIC50180.0 [1], 10000.0 [2]
N-Butyl-N-[3-[4-[2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl]phenoxy]propyl]butan-1-amine;hydrate;hydrochlorideIC502000.0 [1], 2900.0 [2]
4-[4-[(E)-2-(1,3-Benzoxazol-2-yl)ethenyl]phenoxy]-N,N-diethylbutan-1-amine;hydrate;hydrochlorideIC5080.0 [1], 120.0 [2]
2-[5-Methyl-4-(2-methyl-1H-pyrrol-3-yl)-1,3-thiazol-2-yl]guanidine;hydrochlorideIC501000.0 [1], 1300.0 [2]
2-[4-(5-Chloro-1H-indol-3-yl)-1,3-thiazol-2-yl]guanidine;hydrochlorideIC50700.0 [1], 1800.0 [2]
Ranitidine BaseIC5040.0 [1]
PantoprazoleIC501000.0 [1]
LansoprazoleIC50398.11 [1]
2-Methyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine-3-acetonitrileIC5065.0 [1]
TimoprazoleIC50130000.0 [1]
2-((2-Dimethylaminobenzyl)sulfinyl)benzimidazoleIC50700.0 [1]
3-Amino-2-methyl-8-phenylmethoxyimidazo(1,2-a)pyrazineIC508080.0 [1]
3-Butyryl-4-(2-methylphenylamino)-8-methoxyquinolineIC5018000.0 [1]
8-Benzyloxy-2,7-dimethylimidazo[1,2-a]pyridine-3-acetonitrileIC50400.0 [1]
2-Methyl-8-phenethyl-imidazo[1,2-a]pyridin-3-ylamineIC501460.0 [1]
2-(4-Methoxy-2-pyridylmethylsulfinyl)-5-(1,1,2,2-tetrafluoroethoxy)-1H-benzimidazoleIC501258.93 [1]
2-(4-Methyl-12-phenyl-13-oxa-3,6-diazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7-tetraen-5-yl)acetonitrileIC5064.0 [1]
8-(Benzyloxy)-2-methylimidazo[1,2-a]pyridin-3-amineIC50310.0 [1]
2-Methyl-8-(2-phenylethyl)imidazo[1,2-a]pyridine-3-acetonitrileIC50130.0 [1]
[2-Methyl-8-(3-phenyl-propenyl)-imidazo[1,2-a]pyridin-3-yl]-acetonitrileIC503800.0 [1]
2,3-Dimethyl-8-styryl-imidazo[1,2-a]pyridineIC50990.0 [1]
2,3-Dimethyl-8-((Z)-styryl)-imidazo[1,2-a]pyridineIC5017500.0 [1]
1-(4-Phenyl-1,3-thiazol-2-yl)guanidineIC5040000.0 [1]
[2-Methyl-8-(3-phenyl-allyl)-imidazo[1,2-a]pyridin-3-yl]-acetonitrileIC50442000.0 [1]
2,2-Difluoro-6-((4-methoxy-3-methyl-2-pyridyl)methylsulfinyl)-5H-(1,3)-dioxolo(4,5-f)benzimidazoleIC501000.0 [1]
2-Methyl-8-(3-phenyl-propenyl)-imidazo[1,2-a]pyridin-3-ylamineIC5014100.0 [1]
4-Methoxy-2-[(6-methoxy-1H-benzimidazol-2-yl)sulfinylmethyl]-3,5-dimethyl-anilineIC502100.0 [1]
6-(1H-Benzimidazol-2-ylsulfinylmethyl)-2,3-dimethyl-anilineIC50600.0 [1]
2-(1H-Benzimidazol-2-ylsulfinylmethyl)-3,6-dimethyl-anilineIC50800.0 [1]
2-[(6-Methoxy-1H-benzimidazol-2-yl)sulfinylmethyl]anilineIC5011000.0 [1]
2-(1H-Benzimidazol-2-ylsulfinylmethyl)-4-methoxy-3,5-dimethyl-anilineIC50200.0 [1]
(8-Benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-yl)-methanolIC50530.0 [1]
2-[2-(4-Methoxy-3,5-dimethylpyridin-2-yl)ethyl]-2-methyl-5-(trifluoromethyl)-3H-1,3-benzothiazoleIC5024000.0 [1]
2-(2,4-Dimethoxy-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamideIC50590.0 [1]
2-(2,4-Diethoxy-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamideIC50400.0 [1]
2-(2,4-Dimethoxy-6-methyl-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamideIC50460.0 [1]
2-[2-(2-Fluoro-ethoxy)-4-methoxy-phenylmethanesulfinyl]-N-pyridin-4-yl-nicotinamideIC501700.0 [1]
2-(2,4-Dimethoxy-3-methyl-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamideIC5016600.0 [1]
2-[2-(2-Hydroxy-ethoxy)-4-methoxy-phenylmethanesulfinyl]-N-pyridin-4-yl-nicotinamideIC5059000.0 [1]
2-(5-Bromo-2,4-dimethoxy-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamideIC501900.0 [1]
5-Difluoromethoxy-2-[(4,5-dimethoxy-2-pyridinyl)methylsulfinyl]-1H-benzimidazoleIC5031622.78 [1]
2-[[Amino(benzylamino)methylene]amino]-4-(1H-indol-2-yl)thiazoleIC5016000.0 [1]
2-(2,6-Dimethoxy-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamideIC5026000.0 [1]
2-(2-Ethoxy-4-methoxy-phenylmethanesulfinyl)-N-pyridin-4-yl-nicotinamideIC50450.0 [1]
2-[4-(1H-Indol-3-yl)-1,3-thiazol-2-yl]guanidine;hydrochlorideIC509000.0 [1]
2-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]guanidine;hydrobromideIC5035000.0 [1]
2-[4-(3-Hydroxyphenyl)-1,3-thiazol-2-yl]guanidine;hydrobromideIC5023000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Potassium-transporting ATPase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/potassium-transporting-atpase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Potassium-transporting ATPase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/potassium-transporting-atpase-inhibitors-ic50-ki.
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