Potassium-transporting ATPase alpha chain 2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Ouabain	IC50	200000.0 [1]
	Digitoxigenin	IC50	80.0 [1]
	Androstane-3,6,17-trione, 3-[O-(2-aminoethyl)oxime], (5a)-	IC50	200.0 [1]
	(E)-3-[(3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]prop-2-enal	IC50	60.0 [1]
	3-[(1R)-1-[(2R,4Bs,7S,8aR)-7-hydroxy-2,4b-dimethyl-1-oxo-4,4a,5,6,7,8,8a,9,10,10a-decahydro-3H-phenanthren-2-yl]propyl]-2H-furan-5-one	IC50	200.0 [1]
	2-(Dimethylamino)ethyl (E,4R)-4-[(2R,4bS,7S,8aR)-7-hydroxy-2,4b-dimethyl-1-oxo-4,4a,5,6,7,8,8a,9,10,10a-decahydro-3H-phenanthren-2-yl]hex-2-enoate	IC50	250.0 [1]
	2-(Diaminomethyleneamino)-4-(2-methyl-1H-pyrrol-4-yl)thiazole	IC50	100000.0 [1]
	(3E,5S,8R,9S,10R,13S,14S)-3-[2-(Dimethylamino)ethoxyimino]-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione	IC50	12000.0 [1]
	2-(Dimethylamino)ethyl (E)-3-[(3S,5R,8R,9S,10S,13R,14S,17R)-3,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]prop-2-enoate	IC50	30.0 [1]
	2-(Dimethylamino)ethyl (2E)-2-[(1R,4bR,7S,8aR)-7-hydroxy-1,4b,8,8-tetramethyl-10-oxo-1,3,4,4a,5,6,7,8a,9,10a-decahydrophenanthren-2-ylidene]acetate	IC50	100.0 [1]
	2-(Dimethylamino)ethyl (E,4S)-4-[(2S,4bS,7S,8aR)-7-hydroxy-2,4b-dimethyl-1-oxo-4,4a,5,6,7,8,8a,9,10,10a-decahydro-3H-phenanthren-2-yl]hex-2-enoate	IC50	120.0 [1]
	3-[(1S)-1-[(2S,4Bs,7S,8aR)-7-hydroxy-2,4b-dimethyl-1,3,4,4a,5,6,7,8,8a,9,10,10a-dodecahydrophenanthren-2-yl]propyl]-2H-furan-5-one	IC50	130.0 [1]
	Methyl (E)-3-[(3S,5R,8R,9S,10S,13R,14S,17R)-3,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]prop-2-enoate	IC50	350.0 [1]
	2-(Dimethylamino)ethyl (E)-3-[(3S,5R,8R,9S,10S,13S,14S,17S)-3,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]prop-2-enoate	IC50	5890.0 [1]
	(3E,5S,6R,8R,9S,10R,13S,14S)-3-[2-(Dimethylamino)ethoxyimino]-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-6,17-diol	IC50	100000.0 [1]
	(2R,3Z,5S,8R,9S,10R,13S,14S)-3-(2-Aminoethoxyimino)-2,10,13-trimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione	IC50	25000.0 [1]
	(3E,4S,5S,8R,9S,10R,13S,14S)-3-(2-Aminoethoxyimino)-4,10,13-trimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione	IC50	6000.0 [1]
	[2-[3-[6-[3-[(5R,6As,6bR,12aR)-10-[6-[2-[2-[4,5-dihydroxy-3-(3,4,5-trihydroxyoxan-2-yl)oxyoxan-2-yl]ethoxy]ethyl]-3,4,5-trihydroxyoxan-2-yl]oxy-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carbonyl]peroxypropyl]-5-[[5-[8-[3,5-dihydroxy-4-(3,4,5-trihydroxyoxan-2-yl)oxyoxan-2-yl]octoxy]-3,4-dihydroxy-6-methyloxan-2-yl]methoxy]-3,4-dihydroxyoxan-2-yl]propoxymethyl]-5-hydroxy-3-[(6S)-6-hydroxy-2,6-dimethylocta-2,7-dienoyl]oxy-6-methyloxan-4-yl] (2E,6S)-6-hydroxy-2-(hydroxymethyl)-6-methylocta-2,7-dienoate	IC50	400000.0 [1]
	Methyl (5R,6aS,6bR,12aR)-10-[6-[2-[2-[4,5-dihydroxy-3-(3,4,5-trihydroxyoxan-2-yl)oxyoxan-2-yl]ethoxy]ethyl]-3,4,5-trihydroxyoxan-2-yl]oxy-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate	IC50	25000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 19 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Potassium-transporting ATPase alpha chain 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/potassium-transporting-atpase-alpha-chain-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 21). Quest Database™ Potassium-transporting ATPase alpha chain 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/potassium-transporting-atpase-alpha-chain-2-inhibitors-ic50-ki.
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