Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride	IC50	31.62 [1]
	Auglurant	IC50	100000.0 [1]
	6-[[[1-[2-(7-Methoxy-2-oxoquinoxalin-1-yl)ethyl]piperidin-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one	IC50	100000.0 [1]
	2-Methoxy-N-{[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl}benzamide	IC50	5011.87 [1]
	CID 16015637	IC50	50118.72 [1]
	2-Methoxy-N-[2-(4-methylphenyl)-2-(4-methylpiperazin-1-yl)ethyl]benzamide	IC50	19952.62 [1]
	2-Ethoxy-N-[[1-(4-propan-2-ylpiperazin-1-yl)cyclohexyl]methyl]benzamide	IC50	316.23 [1]
	2-Methoxy-N-[2-(4-methylpiperazin-1-yl)ethyl]benzamide	IC50	199526.23 [1]
	2-Ethoxy-N-{[1-(4-ethylpiperazin-1-yl)cyclohexyl]methyl}benzamide	IC50	158.49 [1]
	2-Chloro-N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]benzamide	IC50	31622.78 [1]
	2-Ethoxy-N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]benzamide	IC50	1258.93 [1]
	2-[[[4-[(1R)-1-Amino-2-(7-fluoro-2-oxoquinoxalin-1-yl)ethyl]cyclohexyl]amino]methyl]-8H-pyrimido[5,4-b][1,4]oxazin-7-one	IC50	100000.0 [1]
	2-Ethoxy-N-((1-(piperazin-1-YL)cyclohexyl)methyl)benzamide	IC50	3981.07 [1]
	2-Methoxy-N-[(2-piperidin-1-yl-1,3-dihydroinden-2-yl)methyl]benzamide	IC50	199526.23 [1]
	2-Ethoxy-N-[(1-piperidin-1-ylcyclohexyl)methyl]benzamide	IC50	39810.72 [1]
	2-Ethoxy-N-[[1-(4-methylpiperazin-1-yl)cyclopentyl]methyl]benzamide	IC50	5011.87 [1]
	2-Methoxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide	IC50	19952.62 [1]
	N-[[2-(4-Methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]-2-phenylmethoxybenzamide	IC50	2511.89 [1]
	N-[[2-(4-Methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]-2-(trifluoromethoxy)benzamide	IC50	199526.23 [1]
	2-Ethoxy-N-[[2-(4-propan-2-ylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide	IC50	3162.28 [1]
	2-Ethoxy-N-[[4-(4-propan-2-ylpiperazin-1-yl)oxan-4-yl]methyl]benzamide	IC50	3981.07 [1]
	2-Fluoro-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide	IC50	199526.23 [1]
	2-Methyl-N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]benzamide	IC50	199526.23 [1]
	N-[[1-(4-Cyclopropylpiperazin-1-yl)cyclohexyl]methyl]-2-ethoxybenzamide	IC50	316.23 [1]
	N-[[1-(4-Cyclobutylpiperazin-1-yl)cyclohexyl]methyl]-2-ethoxybenzamide	IC50	794.33 [1]
	2-Methoxy-N-[[1-(4-propan-2-ylpiperazin-1-yl)cyclohexyl]methyl]benzamide	IC50	794.33 [1]
	2-Ethoxy-N-[[1-(4-phenylpiperazin-1-yl)cyclohexyl]methyl]benzamide	IC50	100000.0 [1]
	2-Ethoxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide	IC50	5011.87 [1]
	3-Methoxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide	IC50	199526.23 [1]
	2-Chloro-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide	IC50	158489.32 [1]
	2-Propan-2-yloxy-N-[[1-(4-propan-2-ylpiperazin-1-yl)cyclohexyl]methyl]benzamide	IC50	1584.89 [1]
	N-[[1-(4-Cyclopentylpiperazin-1-yl)cyclohexyl]methyl]-2-ethoxybenzamide	IC50	794.33 [1]
	2-Methoxy-N-[[2-(4-methylpiperazin-1-yl)-3,4-dihydro-1H-naphthalen-2-yl]methyl]benzamide	IC50	6309.57 [1]
	2-Hydroxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide	IC50	199526.23 [1]
	2-Methoxy-N-[[1-phenyl-4-(4-propan-2-ylpiperazin-1-yl)piperidin-4-yl]methyl]benzamide	IC50	5011.87 [1]
	4-Methoxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamide	IC50	199526.23 [1]
	2-Ethoxy-N-[(2-piperidin-1-yl-1,3-dihydroinden-2-yl)methyl]benzamide	IC50	39810.72 [1]
	2-Ethyl-N-[[1-(4-propan-2-ylpiperazin-1-yl)cyclohexyl]methyl]benzamide	IC50	79432.82 [1]
	N-[[1-[2-(Tert-butylcarbamoylamino)ethyl]-4-(hydroxymethyl)piperidin-4-yl]methyl]-3,5-dichlorobenzamide	IC50	33000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 39 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/potassium-sodium-hyperpolarization-activated-cyclic-nucleotide-gated-channel-4-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 21). Quest Database™ Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/potassium-sodium-hyperpolarization-activated-cyclic-nucleotide-gated-channel-4-inhibitors-ic50-ki.
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