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Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chlorideIC50158.49 [1]
2-Methoxy-N-{[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl}benzamideIC50398.11 [1]
CID 16015637IC50199526.23 [1]
2-Methoxy-N-[2-(4-methylphenyl)-2-(4-methylpiperazin-1-yl)ethyl]benzamideIC502511.89 [1]
2-Ethoxy-N-[[1-(4-propan-2-ylpiperazin-1-yl)cyclohexyl]methyl]benzamideIC5015.85 [1]
2-Methoxy-N-[2-(4-methylpiperazin-1-yl)ethyl]benzamideIC50199526.23 [1]
2-Ethoxy-N-{[1-(4-ethylpiperazin-1-yl)cyclohexyl]methyl}benzamideIC5031.62 [1]
2-Chloro-N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]benzamideIC50199526.23 [1]
2-Ethoxy-N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]benzamideIC50125.89 [1]
2-Ethoxy-N-((1-(piperazin-1-YL)cyclohexyl)methyl)benzamideIC50398.11 [1]
2-Methoxy-N-[(2-piperidin-1-yl-1,3-dihydroinden-2-yl)methyl]benzamideIC5050118.72 [1]
2-Ethoxy-N-[(1-piperidin-1-ylcyclohexyl)methyl]benzamideIC5015848.93 [1]
2-Ethoxy-N-[[1-(4-methylpiperazin-1-yl)cyclopentyl]methyl]benzamideIC50398.11 [1]
2-Methoxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamideIC501258.93 [1]
N-[[2-(4-Methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]-2-phenylmethoxybenzamideIC50630.96 [1]
N-[[2-(4-Methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]-2-(trifluoromethoxy)benzamideIC5025118.86 [1]
2-Ethoxy-N-[[2-(4-propan-2-ylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamideIC50630.96 [1]
2-Ethoxy-N-[[4-(4-propan-2-ylpiperazin-1-yl)oxan-4-yl]methyl]benzamideIC50316.23 [1]
2-Fluoro-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamideIC5025118.86 [1]
2-Methyl-N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]benzamideIC5063095.73 [1]
N-[[1-(4-Cyclopropylpiperazin-1-yl)cyclohexyl]methyl]-2-ethoxybenzamideIC5050.12 [1]
N-[[1-(4-Cyclobutylpiperazin-1-yl)cyclohexyl]methyl]-2-ethoxybenzamideIC5079.43 [1]
2-Methoxy-N-[[1-(4-propan-2-ylpiperazin-1-yl)cyclohexyl]methyl]benzamideIC5031.62 [1]
2-Ethoxy-N-[[1-(4-phenylpiperazin-1-yl)cyclohexyl]methyl]benzamideIC50199526.23 [1]
2-Ethoxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamideIC50398.11 [1]
3-Methoxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamideIC5063095.73 [1]
2-Chloro-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamideIC5019952.62 [1]
2-Propan-2-yloxy-N-[[1-(4-propan-2-ylpiperazin-1-yl)cyclohexyl]methyl]benzamideIC50251.19 [1]
N-[[1-(4-Cyclopentylpiperazin-1-yl)cyclohexyl]methyl]-2-ethoxybenzamideIC50199.53 [1]
2-Methoxy-N-[[2-(4-methylpiperazin-1-yl)-3,4-dihydro-1H-naphthalen-2-yl]methyl]benzamideIC501584.89 [1]
2-Hydroxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamideIC50199526.23 [1]
2-Methoxy-N-[[1-phenyl-4-(4-propan-2-ylpiperazin-1-yl)piperidin-4-yl]methyl]benzamideIC50630.96 [1]
4-Methoxy-N-[[2-(4-methylpiperazin-1-yl)-1,3-dihydroinden-2-yl]methyl]benzamideIC50100000.0 [1]
2-Ethoxy-N-[(2-piperidin-1-yl-1,3-dihydroinden-2-yl)methyl]benzamideIC5015848.93 [1]
2-Ethyl-N-[[1-(4-propan-2-ylpiperazin-1-yl)cyclohexyl]methyl]benzamideIC50199526.23 [1]
Items per page: 1 - 10 of 35
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References

This online tool may be cited as follows

MLA

"Quest Database™ Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/potassium-sodium-hyperpolarization-activated-cyclic-nucleotide-gated-channel-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/potassium-sodium-hyperpolarization-activated-cyclic-nucleotide-gated-channel-1-inhibitors-ic50-ki.
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