Poly [ADP-ribose] polymerase 4 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one	IC50	4365.16 [1], 5011.87 [2]
	Niraparib	IC50	330.0 [1], 446.68 [2]
	Olaparib	IC50	407.38 [1]
	N~2~,N~2~-Dimethyl-N~1~-(6-oxo-5,6-dihydrophenanthridin-2-YL)glycinamide	IC50	758.58 [1]
	Veliparib	IC50	3467.37 [1]
	Rucaparib	IC50	831.76 [1]
	Bmn-673 8R,9S	IC50	257.04 [1]
	4-Methoxybenzamide	IC50	65000.0 [1]
	4,4'-Oxydibenzamide	IC50	23000.0 [1]
	4-Quinazolinol, 5,6,7,8-tetrahydro-2-(4-methyl-1-piperazinyl)-	IC50	17000.0 [1]
	Morpholin-4-Yl[4-(Tetrazolo[1,5-A]quinoxalin-4-Ylamino)phenyl]methanone	IC50	5011.87 [1]
	2-(4-Tert-Butylphenyl)-2,3-dihydroquinazoline-4(1H)-one	IC50	100000.0 [1]
	4-(4-Carbamoylphenoxy)benzoic acid	IC50	100000.0 [1]
	4-[(2-Fluorophenyl)methoxy]benzamide	IC50	100000.0 [1]
	N-{4-[(2-Chlorophenyl)(Pyrimidin-4-Yl)carbamoyl]phenyl}-4-Methoxybenzamide	IC50	100000.0 [1]
	1-[3-[4-(2-Chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-2-oxo-3H-benzimidazole-5-carbonitrile	IC50	100000.0 [1]
	2-(4-((Pyridin-4-Yl)methyl)piperazin-1-Yl)-3,4,5,6,7,8-Hexahydroquinazolin-4-One	IC50	33000.0 [1]
	4-[3-(4-Oxo-3H-quinazolin-2-yl)propanoylamino]-N-quinolin-8-ylbenzamide	IC50	69000.0 [1]
	4-[3-(8-Methyl-4-oxo-3H-quinazolin-2-yl)propanoylamino]-N-quinolin-8-ylbenzamide	IC50	65000.0 [1]
	N-(4-Propan-2-ylphenyl)tetrazolo[1,5-a]quinoxalin-4-amine	IC50	5011.87 [1]
	2-(3-Pyrazin-2-ylpropanoyl)-2,11-diazatricyclo[7.3.1.05,13]trideca-5(13),6,8-trien-10-one	IC50	660.0 [1]
	2-(2-Pyridin-3-ylacetyl)-2,11-diazatricyclo[7.3.1.05,13]trideca-5(13),6,8-trien-10-one	IC50	440.0 [1]
	4-(4-Formyl-phenoxy)-benzamide	IC50	100000.0 [1]
	1,2-Dihydro-2-(4-isopropylphenyl)-4(3H)-quinazolinone	IC50	100000.0 [1]
	[4-(1-Methylimidazole-4-carbonyl)piperazin-1-yl]-[4-(tetrazolo[1,5-a]quinoxalin-4-ylamino)phenyl]methanone	IC50	5011.87 [1]
	(4-Pyrimidin-2-ylpiperazin-1-yl)-[4-(tetrazolo[1,5-a]quinoxalin-4-ylamino)phenyl]methanone	IC50	5011.87 [1]
	N-[3-Chloranyl-4-[[4-(4-Methoxyphenyl)oxan-4-Yl]methylcarbamoyl]phenyl]furan-2-Carboxamide	IC50	100000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 27 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Poly [ADP-ribose] polymerase 4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/poly-adp-ribose-polymerase-4-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, November 21). Quest Database™ Poly [ADP-ribose] polymerase 4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/poly-adp-ribose-polymerase-4-inhibitors-ic50-ki.
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