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Poly [ADP-ribose] polymerase 14 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
4,4'-OxydibenzamideIC5010000.0 [1], 23000.0 [2], 23400.0 [3]
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-oneIC505011.87 [1], 5888.44 [2]
3-[[(Z)-4-[4-(4-Chlorophenyl)piperazin-1-yl]-4-oxobut-2-enoyl]amino]benzamideIC50160.0 [1], 616.6 [2]
3-[[(Z)-4-[4-(4-Fluorophenyl)piperazin-1-yl]-4-oxobut-2-enoyl]amino]benzamideIC50700.0 [1], 707.95 [2]
N~2~,N~2~-Dimethyl-N~1~-(6-oxo-5,6-dihydrophenanthridin-2-YL)glycinamideIC504168.69 [1]
VeliparibIC5089125.09 [1]
RucaparibIC508912.51 [1]
NiraparibIC501737.8 [1]
Bmn-673 8R,9SIC5025118.86 [1]
4-MethoxybenzamideIC5010000.0 [1]
5-(2-Oxo-2-phenylethoxy)isoquinolin-1(2H)-oneIC505754.4 [1]
Morpholin-4-Yl[4-(Tetrazolo[1,5-A]quinoxalin-4-Ylamino)phenyl]methanoneIC505011.87 [1]
2-[4-[6-[(3R,5S)-3,5-Dimethylpiperazin-1-yl]-4-methylpyridin-3-yl]phenyl]-7-methyl-3H-pyrrolo[2,3-d]pyrimidin-4-oneIC502691.53 [1]
(2z)-4-[(3-Carbamoylphenyl)amino]-4-Oxobut-2-Enoic AcidIC5020000.0 [1]
4-(4-Carbamoylphenoxy)benzoic acidIC5010000.0 [1]
(2E)-4-[(3-Carbamoylphenyl)amino]-4-oxobut-2-enoic acidIC5020000.0 [1]
4-[(2-Fluorophenyl)methoxy]benzamideIC5010000.0 [1]
N-{4-[(2-Chlorophenyl)(Pyrimidin-4-Yl)carbamoyl]phenyl}-4-MethoxybenzamideIC5010000.0 [1]
(Z)-4-(3-Carbamoylanilino)-3-methyl-4-oxobut-2-enoic acidIC5020000.0 [1]
(Z)-4-(3-Carbamoylanilino)-2-methyl-4-oxobut-2-enoic acidIC5020000.0 [1]
2-[(3-Carbamoylphenyl)carbamoyl]cyclopentene-1-carboxylic acidIC5020000.0 [1]
3-(3,4-Dimethyl-2,5-dioxopyrrol-1-yl)benzamideIC5020000.0 [1]
(Z)-N'-(3-Carbamoylphenyl)-N-methylbut-2-enediamideIC5020000.0 [1]
(E)-N'-(3-Carbamoylphenyl)-N-methylbut-2-enediamideIC5018620.87 [1]
3-[[(Z)-4-Oxo-4-pyrrolidin-1-ylbut-2-enoyl]amino]benzamideIC5020000.0 [1]
(Z)-N-(3-Carbamoylphenyl)-N',N'-diethylbut-2-enediamideIC5020000.0 [1]
Methyl (Z)-4-(3-carbamoylanilino)-4-oxobut-2-enoateIC501659.59 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]methanesulfonamideIC50900.0 [1]
1-[3-[4-(2-Chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-2-oxo-3H-benzimidazole-5-carbonitrileIC5010000.0 [1]
4-[3-[4-(4-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamideIC505200.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]acetamideIC50720.0 [1]
4-[3-(4-Oxo-3H-quinazolin-2-yl)propanoylamino]-N-quinolin-8-ylbenzamideIC50100000.0 [1]
4-[3-(8-Methyl-4-oxo-3H-quinazolin-2-yl)propanoylamino]-N-quinolin-8-ylbenzamideIC50100000.0 [1]
3-[3-[4-(2-Fluorophenyl)piperazin-1-yl]-2,5-dioxopyrrolidin-1-yl]benzamideIC5020000.0 [1]
3-[[(Z)-4-Oxo-4-(4-pyrimidin-2-ylpiperazin-1-yl)but-2-enoyl]amino]benzamideIC502818.38 [1]
3-[[(Z)-4-[4-(4-Fluorophenyl)piperidin-1-yl]-4-oxobut-2-enoyl]amino]benzamideIC50275.42 [1]
3-[[(Z)-4-Oxo-4-(4-phenylpiperazin-1-yl)but-2-enoyl]amino]benzamideIC50891.25 [1]
3-[[(Z)-4-[4-(4-Methoxyphenyl)piperazin-1-yl]-4-oxobut-2-enoyl]amino]benzamideIC503388.44 [1]
3-[[(Z)-4-Oxo-4-(3-phenylpiperidin-1-yl)but-2-enoyl]amino]benzamideIC50690.0 [1]
Ethyl 2-[1-[(Z)-4-(3-carbamoylanilino)-4-oxobut-2-enoyl]piperidin-4-yl]acetateIC50407.38 [1]
3-[[(Z)-4-Oxo-4-[4-(2-phenylethyl)piperidin-1-yl]but-2-enoyl]amino]benzamideIC50676.08 [1]
3-[[(Z)-4-[4-(2-Fluorophenyl)piperazin-1-yl]-4-oxobut-2-enoyl]amino]benzamideIC50407.38 [1]
3-[[(Z)-4-(2-Benzylpiperidin-1-yl)-4-oxobut-2-enoyl]amino]benzamideIC503500.0 [1]
3-[[(Z)-4-Oxo-4-(3-phenoxypiperidin-1-yl)but-2-enoyl]amino]benzamideIC501400.0 [1]
3-[[(Z)-4-(4-Benzylpiperidin-1-yl)-4-oxobut-2-enoyl]amino]benzamideIC50446.68 [1]
Tert-butyl 4-[(Z)-4-(3-carbamoylanilino)-4-oxobut-2-enoyl]piperazine-1-carboxylateIC50371.54 [1]
3-[[(Z)-4-Oxo-4-(2-phenylpiperidin-1-yl)but-2-enoyl]amino]benzamideIC501100.0 [1]
3-[[(Z)-4-Oxo-4-(4-phenylpiperidin-1-yl)but-2-enoyl]amino]benzamideIC502238.72 [1]
3-[[(Z)-4-Oxo-4-[4-(4-phenylphenyl)piperazin-1-yl]but-2-enoyl]amino]benzamideIC504168.69 [1]
4-[3-(3-Phenylpiperidine-1-carbonyl)phenoxy]benzamideIC503600.0 [1]
4-[3-[4-(3-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamideIC501500.0 [1]
4-[3-[4-(3-Fluorophenyl)piperazine-1-carbonyl]phenoxy]benzamideIC504786.3 [1]
4-[3-[4-(4-Chlorophenyl)piperazine-1-carbonyl]phenoxy]benzamideIC504677.35 [1]
4-[3-(2-Phenylpiperidine-1-carbonyl)phenoxy]benzamideIC504265.8 [1]
4-[3-(4-Phenylpiperazine-1-carbonyl)phenoxy]benzamideIC501047.13 [1]
4-[3-[4-(4-Fluorophenyl)-4-hydroxypiperidine-1-carbonyl]phenoxy]benzamideIC501288.25 [1]
4-[3-[4-(2-Fluorophenyl)piperazine-1-carbonyl]phenoxy]benzamideIC501071.52 [1]
4-[3-[4-(3,4-Difluorophenyl)piperazine-1-carbonyl]phenoxy]benzamideIC50691.83 [1]
4-[3-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]phenoxy]benzamideIC505754.4 [1]
4-[3-(4-Phenylpiperidine-1-carbonyl)phenoxy]benzamideIC502430.0 [1]
4-[3-[4-(4-Fluorophenyl)piperazine-1-carbonyl]phenoxy]benzamideIC50776.25 [1]
4-[3-(3-Phenylpyrrolidine-1-carbonyl)phenoxy]benzamideIC503235.94 [1]
2-(9H-Carbazol-1-yl)-4-(trifluoromethyl)anilineIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-(2,5-dimethylphenyl)acetamideIC5044600.0 [1]
N-[3-(9H-Carbazol-1-yl)pyridin-4-yl]acetamideIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]benzamideIC501900.0 [1]
2-(9H-Carbazol-1-yl)-3-methylanilineIC5050000.0 [1]
N-[2-(9-Hydroxy-9H-fluoren-1-yl)phenyl]acetamideIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-(4-fluorophenyl)acetamideIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]pentanamideIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-[3-(trifluoromethyl)phenyl]acetamideIC507100.0 [1]
N-[2-(9H-Carbazol-1-yl)pyridin-3-yl]acetamideIC5050000.0 [1]
N-[2-(6,7,8,9-Tetrahydro-5H-carbazol-1-yl)phenyl]acetamideIC501100.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]cyclohexanecarboxamideIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-(6-cyanopyridin-3-yl)acetamideIC503500.0 [1]
2-(1,3-Benzodioxol-5-yl)-N-[2-(9H-carbazol-1-yl)phenyl]acetamideIC506900.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-(3,4-dichlorophenyl)acetamideIC506300.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-1-(3-cyanophenyl)methanesulfonamideIC50660.0 [1]
N-[2-(2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indol-6-yl)phenyl]acetamideIC5050000.0 [1]
1-[2-(Dimethylsulfamoylamino)phenyl]-9H-carbazoleIC502500.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-pyrazin-2-ylacetamideIC502100.0 [1]
N-[2-(9-Oxofluoren-1-yl)phenyl]acetamideIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)-3-methylphenyl]acetamideIC501700.0 [1]
N-[2-(9H-Carbazol-1-yl)-5-methylphenyl]methanesulfonamideIC501100.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-(3-fluorophenyl)acetamideIC504200.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]propane-1-sulfonamideIC502900.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-1-(5-cyano-2-fluorophenyl)methanesulfonamideIC501200.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-(2-cyanopyridin-4-yl)acetamideIC502400.0 [1]
N-[2-(7,8-Dichloro-9H-carbazol-1-yl)phenyl]acetamideIC501400.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-pyridin-3-ylacetamideIC501100.0 [1]
N-[2-(9-Benzylcarbazol-1-yl)phenyl]acetamideIC5050000.0 [1]
N-[2-(4-Oxo-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-2,5,7,9(16),10,12,14-heptaen-3-yl)phenyl]acetamideIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-(dimethylamino)acetamideIC505500.0 [1]
N-[2-(6-Methoxy-9H-carbazol-1-yl)phenyl]acetamideIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]-2-(4-chlorophenyl)acetamideIC506200.0 [1]
N-(2-Dibenzofuran-4-ylphenyl)acetamideIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]propanamideIC501000.0 [1]
2-(9H-Carbazol-1-yl)-5-methylanilineIC5050000.0 [1]
N-[2-(9-Methylcarbazol-1-yl)phenyl]acetamideIC5050000.0 [1]
N-[2-(9H-Carbazol-1-yl)phenyl]butane-1-sulfonamideIC503300.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Poly [ADP-ribose] polymerase 14 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/poly-adp-ribose-polymerase-14-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Poly [ADP-ribose] polymerase 14 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/poly-adp-ribose-polymerase-14-inhibitors-ic50-ki.
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