Poly [ADP-ribose] polymerase 10 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	4,4'-Oxydibenzamide	IC50	329.0 [1], 330.0 [2], 600.0 [3], 640.0 [4], 1350.0 [5]
	Olaparib	IC50	1258.93 [1], 9332.54 [2]
	N~2~,N~2~-Dimethyl-N~1~-(6-oxo-5,6-dihydrophenanthridin-2-YL)glycinamide	IC50	5888.44 [1], 6760.83 [2]
	Veliparib	IC50	1905.46 [1], 43651.58 [2]
	Rucaparib	IC50	562.34 [1], 2290.87 [2]
	Niraparib	IC50	1949.84 [1], 3311.31 [2]
	3,4-Dihydroisoquinolin-1(2H)-one	IC50	30000.0 [1], 128824.96 [2]
	4-[(2-Fluorophenyl)methoxy]benzamide	IC50	234.42 [1], 2000.0 [2]
	7-Methoxy-3,4-dihydroisoquinolin-1(2H)-one	IC50	100000.0 [1], 169824.37 [2]
	7-Methyl-3,4-dihydroisoquinolin-1(2H)-one	IC50	100000.0 [1], 112201.85 [2]
	7-Fluoro-3,4-dihydroisoquinolin-1(2H)-one	IC50	72443.6 [1], 100000.0 [2]
	4-(4-Formyl-phenoxy)-benzamide	IC50	616.6 [1], 1000.0 [2]
	7-(Trifluoromethyl)-3,4-dihydroisoquinolin-1(2H)-one	IC50	66069.34 [1], 100000.0 [2]
	Bmn-673 8R,9S	IC50	7762.47 [1]
	4-Methoxybenzamide	IC50	2800.0 [1]
	5-(2-Oxo-2-phenylethoxy)isoquinolin-1(2H)-one	IC50	7079.46 [1]
	4-Quinazolinol, 5,6,7,8-tetrahydro-2-(4-methyl-1-piperazinyl)-	IC50	10000.0 [1]
	7-Chloro-3,4-dihydroisoquinolin-1(2H)-one	IC50	100000.0 [1]
	CID 21950586	IC50	1148.15 [1]
	Morpholin-4-Yl[4-(Tetrazolo[1,5-A]quinoxalin-4-Ylamino)phenyl]methanone	IC50	5011.87 [1]
	4-(Benzyloxy)benzamide	IC50	1348.96 [1]
	2-(4-Tert-Butylphenyl)-2,3-dihydroquinazoline-4(1H)-one	IC50	10000.0 [1]
	4-Ethoxybenzamide	IC50	3500.0 [1]
	4-[(4-Fluorobenzyl)oxy]benzamide	IC50	7943.28 [1]
	(2z)-4-[(3-Carbamoylphenyl)amino]-4-Oxobut-2-Enoic Acid	IC50	10715.19 [1]
	4-(4-Carbamoylphenoxy)benzoic acid	IC50	180.0 [1]
	4-[(3-Fluorophenyl)methoxy]benzamide	IC50	3311.31 [1]
	(2E)-4-[(3-Carbamoylphenyl)amino]-4-oxobut-2-enoic acid	IC50	1380.38 [1]
	N-(3-Carbamoyl-phenyl)-succinamic acid	IC50	1905.46 [1]
	4-Cyclobutoxybenzamide	IC50	720.0 [1]
	N-{4-[(2-Chlorophenyl)(Pyrimidin-4-Yl)carbamoyl]phenyl}-4-Methoxybenzamide	IC50	10000.0 [1]
	4-(4-Methoxyphenoxy)benzamide	IC50	1400.0 [1]
	(Z)-4-(5-Carbamoyl-2-methoxyanilino)-4-oxobut-2-enoic acid	IC50	20000.0 [1]
	(Z)-4-(3-Carbamoylanilino)-3-methyl-4-oxobut-2-enoic acid	IC50	20000.0 [1]
	(Z)-4-(3-Carbamoylanilino)-2-methyl-4-oxobut-2-enoic acid	IC50	14125.38 [1]
	4-(3-Carbamoylanilino)-3-methoxy-4-oxobutanoic acid	IC50	7244.36 [1]
	2-[(3-Carbamoylphenyl)carbamoyl]cyclopentene-1-carboxylic acid	IC50	2884.03 [1]
	3-(3,4-Dimethyl-2,5-dioxopyrrol-1-yl)benzamide	IC50	2398.83 [1]
	(Z)-N'-(3-Carbamoylphenyl)-N-methylbut-2-enediamide	IC50	1995.26 [1]
	(E)-N'-(3-Carbamoylphenyl)-N-methylbut-2-enediamide	IC50	2089.3 [1]
	3-[[(Z)-4-Oxo-4-pyrrolidin-1-ylbut-2-enoyl]amino]benzamide	IC50	4570.88 [1]
	(Z)-N-(3-Carbamoylphenyl)-N',N'-diethylbut-2-enediamide	IC50	20000.0 [1]
	Methyl (Z)-4-(3-carbamoylanilino)-4-oxobut-2-enoate	IC50	758.58 [1]
	3-(5-Oxohexanoylamino)benzamide	IC50	14454.4 [1]
	3-[(3-Oxocyclopentanecarbonyl)amino]benzamide	IC50	6918.31 [1]
	2-(2,4-Dioxo-1,3-diazinan-1-yl)-N-[2-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)ethyl]benzamide	IC50	2187.76 [1]
	2-(2,4-Dioxo-1,3-diazinan-1-yl)-N-[(4-pyrazol-1-ylphenyl)methyl]benzamide	IC50	50000.0 [1]
	N-[2-(2,4-Dichlorophenyl)ethyl]-2-(2,4-dioxo-1,3-diazinan-1-yl)benzamide	IC50	50000.0 [1]
	N-[2-(4-Bromophenyl)ethyl]-2-(2,4-dioxo-1,3-diazinan-1-yl)benzamide	IC50	50000.0 [1]
	N-[2-(4-Chlorophenyl)ethyl]-2-(2,4-dioxo-1,3-diazinan-1-yl)benzamide	IC50	50000.0 [1]
	N-[(2S)-3-Amino-2-[[2-(6-methoxy-3-oxo-1,2-dihydroinden-1-yl)acetyl]amino]-3-oxopropyl]-2-(2,4-dioxo-1,3-diazinan-1-yl)benzamide	IC50	50000.0 [1]
	1-[2-[4-[2-(6-Methoxy-3-oxo-1,2-dihydroinden-1-yl)acetyl]piperazine-1-carbonyl]phenyl]-1,3-diazinane-2,4-dione	IC50	33884.42 [1]
	1-[3-[4-(2-Chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-2-oxo-3H-benzimidazole-5-carbonitrile	IC50	10000.0 [1]
	4-[3-[4-(4-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamide	IC50	400.0 [1]
	2-(4-((Pyridin-4-Yl)methyl)piperazin-1-Yl)-3,4,5,6,7,8-Hexahydroquinazolin-4-One	IC50	5400.0 [1]
	4-[3-(4-Oxo-3H-quinazolin-2-yl)propanoylamino]-N-quinolin-8-ylbenzamide	IC50	100000.0 [1]
	4-[3-(8-Methyl-4-oxo-3H-quinazolin-2-yl)propanoylamino]-N-quinolin-8-ylbenzamide	IC50	100000.0 [1]
	4-[4-[4-(4-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamide	IC50	1650.0 [1]
	4-[3-[4-(2-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamide	IC50	470.0 [1]
	4-[3-(3-Phenylpiperidine-1-carbonyl)phenoxy]benzamide	IC50	600.0 [1]
	Ethyl 1-[3-(4-carbamoylphenoxy)benzoyl]piperidine-4-carboxylate	IC50	1060.0 [1]
	4-[3-[4-(3-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamide	IC50	250.0 [1]
	4-[3-[4-(3-Fluorophenyl)piperazine-1-carbonyl]phenoxy]benzamide	IC50	467.74 [1]
	4-[3-[4-(4-Chlorophenyl)piperazine-1-carbonyl]phenoxy]benzamide	IC50	2511.89 [1]
	4-[3-(2-Phenylpiperidine-1-carbonyl)phenoxy]benzamide	IC50	1100.0 [1]
	4-[3-(4-Phenylpiperazine-1-carbonyl)phenoxy]benzamide	IC50	1100.0 [1]
	4-[3-[4-(4-Fluorophenyl)-4-hydroxypiperidine-1-carbonyl]phenoxy]benzamide	IC50	387.26 [1]
	4-[3-[4-(2-Fluorophenyl)piperazine-1-carbonyl]phenoxy]benzamide	IC50	457.09 [1]
	4-[4-[4-(3-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamide	IC50	1220.0 [1]
	4-[3-[4-(3,4-Difluorophenyl)piperazine-1-carbonyl]phenoxy]benzamide	IC50	2818.38 [1]
	4-[3-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]phenoxy]benzamide	IC50	2818.38 [1]
	4-[3-(4-Phenylpiperidine-1-carbonyl)phenoxy]benzamide	IC50	580.0 [1]
	4-[3-[4-(4-Fluorophenyl)piperazine-1-carbonyl]phenoxy]benzamide	IC50	1348.96 [1]
	4-[3-(3-Phenylpyrrolidine-1-carbonyl)phenoxy]benzamide	IC50	780.0 [1]
	4-[3-(4-Hydroxy-4-phenylpiperidine-1-carbonyl)phenoxy]benzamide	IC50	1520.55 [1]
	N-(4-Propan-2-ylphenyl)tetrazolo[1,5-a]quinoxalin-4-amine	IC50	5011.87 [1]
	7-Bromo-3,4-dihydroisoquinolin-1(2H)-one	IC50	100000.0 [1]
	4-[(4-Carbamoylphenoxy)methyl]benzamide	IC50	2290.87 [1]
	4-[(3-Bromobenzyl)oxy]benzamide	IC50	2187.76 [1]
	4-[(3,5-Dimethylphenyl)methoxy]benzamide	IC50	4570.88 [1]
	5-(3-Carbamoylanilino)-5-oxopentanoic acid	IC50	7413.1 [1]
	4-(4-Aminophenoxy)benzamide	IC50	1300.0 [1]
	1,2-Dihydro-2-(4-isopropylphenyl)-4(3H)-quinazolinone	IC50	10000.0 [1]
	7-Hydroxy-3,4-dihydro-2H-isoquinolin-1-one	IC50	30000.0 [1]
	4-(Propan-2-yloxy)benzamide	IC50	1300.0 [1]
	4-(2-Phenoxyethoxy)benzamide	IC50	1949.84 [1]
	3-(4-Oxopentanoylamino)benzamide	IC50	1905.46 [1]
	2-[(3-Carbamoylphenyl)carbamoyl]cyclopropane-1-carboxylic acid	IC50	14125.38 [1]
	4-(4-Hydroxyphenoxy)benzamide	IC50	1800.0 [1]
	4-(3-Carbamoylanilino)-2,2-dimethyl-4-oxobutanoic acid	IC50	20000.0 [1]
	4-[(2-Bromophenyl)methoxy]benzamide	IC50	3801.89 [1]
	4-(2-Fluorophenoxy)benzamide	IC50	1698.24 [1]
	Chembl4126054	IC50	510.0 [1]
	[4-(1-Methylimidazole-4-carbonyl)piperazin-1-yl]-[4-(tetrazolo[1,5-a]quinoxalin-4-ylamino)phenyl]methanone	IC50	5011.87 [1]
	4-[(Naphthalen-1-yl)methoxy]benzamide	IC50	1445.44 [1]
	4-(2-Pyridinylmethoxy)benzamide	IC50	1348.96 [1]
	4-[(4-Methylphenyl)methoxy]benzamide	IC50	9332.54 [1]
	Benzamide, 4-(benzoyloxy)-	IC50	7244.36 [1]
	N-[3-Chloranyl-4-[[4-(4-Methoxyphenyl)oxan-4-Yl]methylcarbamoyl]phenyl]furan-2-Carboxamide	IC50	10000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 99 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Poly [ADP-ribose] polymerase 10 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/poly-adp-ribose-polymerase-10-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ Poly [ADP-ribose] polymerase 10 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/poly-adp-ribose-polymerase-10-inhibitors-ic50-ki.
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