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Platelet-activating factor acetylhydrolase IB beta subunit Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
2-[5-[5-(4-Bromophenyl)thiophen-2-yl]-2-oxo-1,3,4-oxadiazol-3-yl]acetamideIC505000.0 [1], 60000.0 [2]
2-[4-Aminobutyl-[2-[4-aminobutyl-[2-[[2-[[2-[[2-[[2-[[2-[5-[5-(4-bromophenyl)thiophen-2-yl]-2-oxo-1,3,4-oxadiazol-3-yl]acetyl]-[(2-phenylacetyl)amino]amino]acetyl]-[(4-chlorobenzoyl)amino]amino]acetyl]-(phenylcarbamoylamino)amino]acetyl]-[(4-methoxybenzoyl)amino]amino]acetyl]-(2-methoxyethyl)amino]acetyl]amino]acetyl]amino]acetamideIC504000.0 [1], 6000.0 [2]
2-[4-Aminobutyl-[2-[4-aminobutyl-[2-[[2-[[2-[[2-[5-[5-(4-bromophenyl)thiophen-2-yl]-2-oxo-1,3,4-oxadiazol-3-yl]acetyl]-[(4-chlorobenzoyl)amino]amino]acetyl]-[[4-(dimethylamino)phenyl]carbamoylamino]amino]acetyl]-(2-methoxyethyl)amino]acetyl]amino]acetyl]amino]acetamideIC504000.0 [1], 7000.0 [2]
N-[2-[[2-[[2-[[2-[[2-[[2-[4-Aminobutyl-[2-[4-aminobutyl-(2-amino-2-oxoethyl)amino]-2-oxoethyl]amino]-2-oxoethyl]-(2-methoxyethyl)amino]-2-oxoethyl]-(1,3-benzodioxol-5-ylmethyl)amino]-2-oxoethyl]-(phenylcarbamoylamino)amino]-2-oxoethyl]-[(4-chlorobenzoyl)amino]amino]-2-oxoethyl]-(3-methoxypropanoylamino)amino]-2-oxoethyl]-2-[5-[5-(4-bromophenyl)thiophen-2-yl]-2-oxo-1,3,4-oxadiazol-3-yl]-N-methylacetamideIC5016000.0 [1], 161000.0 [2]
2-[4-Aminobutyl-[2-[4-aminobutyl-[2-[[2-[1,3-benzodioxol-5-ylmethyl-[2-[[2-[[2-[[2-[5-[5-(4-bromophenyl)thiophen-2-yl]-2-oxo-1,3,4-oxadiazol-3-yl]acetyl]-(3-methoxypropanoylamino)amino]acetyl]-[(4-chlorobenzoyl)amino]amino]acetyl]-(phenylcarbamoylamino)amino]acetyl]amino]acetyl]-(2-methoxyethyl)amino]acetyl]amino]acetyl]amino]acetamideIC503000.0 [1], 106000.0 [2]
N-[2-[[2-[[2-[[2-[[2-[[2-[4-Aminobutyl-[2-[4-aminobutyl-(2-amino-2-oxoethyl)amino]-2-oxoethyl]amino]-2-oxoethyl]-(2-methoxyethyl)amino]-2-oxoethyl]-[(4-methoxybenzoyl)amino]amino]-2-oxoethyl]-(phenylcarbamoylamino)amino]-2-oxoethyl]-[(4-chlorobenzoyl)amino]amino]-2-oxoethyl]-(3-methoxypropanoylamino)amino]-2-oxoethyl]-2-[5-[5-(4-bromophenyl)thiophen-2-yl]-2-oxo-1,3,4-oxadiazol-3-yl]-N-methylacetamideIC5010000.0 [1], 63000.0 [2]
2-[4-Aminobutyl-[2-[4-aminobutyl-[2-[[2-[[2-[[2-[2-[5-(4-bromophenyl)thiophene-2-carbonyl]hydrazinyl]acetyl]-[(4-chlorobenzoyl)amino]amino]acetyl]-(phenylcarbamoylamino)amino]acetyl]-(2-methoxyethyl)amino]acetyl]amino]acetyl]amino]acetamideIC5034000.0 [1], 38000.0 [2]
2-[4-Aminobutyl-[2-[4-aminobutyl-[2-[[2-[[2-[[2-[5-[5-(4-bromophenyl)thiophen-2-yl]-2-oxo-1,3,4-oxadiazol-3-yl]acetyl]-[(4-chlorobenzoyl)amino]amino]acetyl]-(phenylcarbamoylamino)amino]acetyl]-(2-methoxyethyl)amino]acetyl]amino]acetyl]amino]acetamideIC504000.0 [1], 5000.0 [2]
Methoxy arachidonyl fluorophosphonateIC5072.0 [1]
2-[4-Aminobutyl-[2-[4-aminobutyl-[2-[[2-[[(4-bromophenyl)carbamoylamino]-[2-[[2-[5-[5-(4-bromophenyl)thiophen-2-yl]-2-oxo-1,3,4-oxadiazol-3-yl]acetyl]-[(4-chlorobenzoyl)amino]amino]acetyl]amino]acetyl]-(2-methoxyethyl)amino]acetyl]amino]acetyl]amino]acetamideIC505000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Platelet-activating factor acetylhydrolase IB beta subunit Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/platelet-activating-factor-acetylhydrolase-ib-beta-subunit-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Platelet-activating factor acetylhydrolase IB beta subunit Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/platelet-activating-factor-acetylhydrolase-ib-beta-subunit-inhibitors-ic50-ki.
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