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Plasma retinol-binding protein Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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2-[({4-[2-(Trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acidIC500.15 [1], 14.0 [2], 122.0 [3]
2-[[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]benzoic acidIC500.29 [1], 72.7 [2], 3000.0 [3]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methylpyrimidine-4-carboxylic acidIC5012.8 [1], 43.6 [2], 3000.0 [3]
N-(5-Chloro-2-methoxyphenyl)-4-(2-phenylethyl)-1-piperazinecarboxamideIC5030000.0 [1]
2-Oxo-2-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]acetic acidIC503.13 [1], 233.7 [2]
2-[(3Ar,6aS)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methylpyridine-4-carboxylic acidIC5053.3 [1], 228.0 [2]
6-[(3Ar,6aS)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-4-methylpyridine-2-carboxylic acidIC5014.1 [1], 295.0 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-5,6-dimethylpyrimidine-4-carboxylic acidIC5048.8 [1], 123.0 [2]
4-[[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]-6-methylpyridine-3-carboxylic acidIC500.23 [1], 23.9 [2]
2-(4-(2-Trifluoromethylphenyl)piperidine-1-yl)-6-methylpyrimidine-4-carboxylic acid methyl esterIC504.1 [1], 132.0 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methoxypyrimidine-4-carboxylic acidIC5012.8 [1], 81.2 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-5-methylpyrimidine-4-carboxylic acidIC5090.1 [1], 595.0 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]pyridine-3-carboxylic acidIC5043.8 [1], 381.0 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]pyrimidine-4-carboxylic acidIC5020.8 [1], 79.7 [2]
2-[(3As,6aR)-5-[5-fluoro-2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methylpyrimidine-4-carboxylic acidIC5033.4 [1], 46.3 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]pyrimidine-5-carboxylic acidIC50171.0 [1], 1864.0 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-propan-2-ylpyrimidine-4-carboxylic acidIC50153.0 [1], 202.0 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-(trifluoromethyl)pyrimidine-4-carboxylic acidIC509.6 [1], 88.0 [2]
N-[2-(Methylsulfonylcarbamoyl)phenyl]-4-[2-(trifluoromethyl)phenyl]piperidine-1-carboxamideIC506.8 [1], 298.5 [2]
N-[2-(Cyclopropylsulfonylcarbamoyl)phenyl]-4-[2-(trifluoromethyl)phenyl]piperidine-1-carboxamideIC505.31 [1], 244.4 [2]
N-[2-(Benzenesulfonylcarbamoyl)phenyl]-4-[2-(trifluoromethyl)phenyl]piperidine-1-carboxamideIC503.94 [1], 3000.0 [2]
2-[[(1S,5R)-6-[2-(Trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane-3-carbonyl]amino]benzoic acidIC503000.0 [1]
2-[[3-[2-(Trifluoromethyl)phenyl]azetidine-1-carbonyl]amino]benzoic acidIC508.38 [1], 3000.0 [2]
2-[[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]acetic acidIC506.82 [1], 1170.0 [2]
(2S)-2-[[(3Ar,6aS)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]propanoic acidIC505.26 [1], 1480.0 [2]
(2R)-2-[[(3Ar,6aS)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]propanoic acidIC509.19 [1], 3000.0 [2]
(2S)-2-[[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]-2-phenylacetic acidIC500.83 [1], 124.0 [2]
(2R)-2-[[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]-2-phenylacetic acidIC508.34 [1], 1320.0 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methylpyrimidine-4-carboxamideIC503.3 [1], 248.0 [2]
(3Ar,6aS)-2-[4-methyl-6-(2H-tetrazol-5-yl)pyrimidin-2-yl]-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrroleIC507.5 [1], 175.0 [2]
6-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-3-methylpyridine-2-carboxylic acidIC50584.0 [1], 4908.0 [2]
3-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]benzoic acidIC5083.2 [1], 3956.0 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methylpyridine-3-carboxylic acidIC5068.4 [1], 2005.0 [2]
6-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]pyridazine-4-carboxylic acidIC5023.0 [1], 437.0 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-5-methyl-1,3-thiazole-4-carboxylic acidIC5029.3 [1], 495.0 [2]
2-[(3Ar,6aS)-5-(2-chloro-5-fluorophenyl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methylpyrimidine-4-carboxylic acidIC50347.0 [1], 532.0 [2]
2-[(3Ar,6aS)-5-(2-chloro-3-fluorophenyl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methylpyrimidine-4-carboxylic acidIC50137.0 [1], 504.0 [2]
2-[(3As,6aR)-5-[4-(trifluoromethyl)pyridin-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methylpyrimidine-4-carboxylic acidIC5051.8 [1], 821.0 [2]
2-[(3Ar,6aS)-5-[2-(trifluoromethyl)pyridin-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methylpyrimidine-4-carboxylic acidIC5031.1 [1], 719.0 [2]
2-(4-(2-Trifluoromethylphenyl)piperidine-1-yl)-6-methylpyrimidine-4-carboxylic acidIC5035.3 [1], 188.0 [2]
Methyl 6-methyl-2-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]pyrimidine-4-carboxylateIC509.7 [1], 1402.0 [2]
2-(4-(2-Trifluoromethylphenyl)piperazine-1-yl)-6-methylpyrimidine-4-carboxylic acidIC5089.5 [1], 511.0 [2]
2-[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-4-methylpyrimidine-5-carboxylic acidIC5040.8 [1], 523.0 [2]
N-(5-Chloro-2-methoxyphenyl)-4-(2-chlorophenyl)piperazine-1-carboxamideIC50890.0 [1], 1300.0 [2]
N-(5-Chloro-2-methoxyphenyl)-4-(pyridin-2-yl)piperazine-1-carboxamideIC5030000.0 [1]
N-(5-Chloro-2-methoxyphenyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine-1-carboxamideIC50130.0 [1], 230.0 [2]
N-(5-Chloro-2-methoxyphenyl)-4-[(2,6-dichlorophenyl)methyl]piperazine-1-carboxamideIC504500.0 [1], 7500.0 [2]
N-(5-Chloro-2-methoxyphenyl)-4-(7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(12),2(6),8,10-tetraen-12-yl)piperazine-1-carboxamideIC50360.0 [1], 600.0 [2]
N-(5-Chloro-2-methoxyphenyl)-4-[2-(trifluoromethyl)phenyl]piperazine-1-carboxamideIC5017.0 [1], 70.0 [2]
N-(5-Chloro-2-methoxyphenyl)-4-[2-(trifluoromethyl)phenyl]piperidine-1-carboxamideIC5023.0 [1], 160.0 [2]
1-[[3-(Trifluoromethyl)phenyl]methyl]-4-[3-(trifluoromethyl)pyridin-2-yl]piperazineIC5010000.0 [1], 30000.0 [2]
N-(5-Chloro-2-methoxyphenyl)-2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine-1-carboxamideIC50350.0 [1], 450.0 [2]
N-(5-Chloro-2-methoxyphenyl)-4-[3-(trifluoromethyl)pyridin-2-yl]-1,4-diazepane-1-carboxamideIC50480.0 [1], 670.0 [2]
[3-(Trifluoromethyl)phenyl]-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanoneIC50920.0 [1], 2700.0 [2]
Methyl 3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]benzoateIC50600.0 [1], 830.0 [2]
[4-[2-(Trifluoromethyl)phenyl]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanoneIC5076.0 [1], 130.0 [2]
4-(Trifluoromethyl)-2-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidineIC5028.0 [1], 270.0 [2]
(1-Methylimidazol-4-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanoneIC5017.0 [1], 110.0 [2]
(3-Methylimidazol-4-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanoneIC50550.0 [1], 840.0 [2]
[4-[2-(Trifluoromethyl)phenyl]piperidin-1-yl]-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanoneIC50120.0 [1], 240.0 [2]
1,3-Thiazol-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanoneIC503.0 [1], 51.0 [2]
Furan-2-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanoneIC5052.0 [1], 120.0 [2]
Methyl 2-[[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]amino]benzoateIC5018.0 [1], 91.0 [2]
2-[[2-(2-Tert-butylphenoxy)ethyl-methylcarbamoyl]amino]benzoic acidIC500.55 [1], 64.8 [2]
2-[[Methyl-[2-[2-(trifluoromethyl)phenoxy]ethyl]carbamoyl]amino]benzoic acidIC502.65 [1], 1900.0 [2]
2-[(3As,6aR)-2-[2-(trifluoromethyl)phenyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-6-methylpyrimidine-4-carboxylic acidIC5057.4 [1], 140.0 [2]
Methyl 2-[(3aS,6aR)-2-[2-(trifluoromethyl)phenyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-6-methylpyrimidine-4-carboxylateIC503.9 [1], 74.0 [2]
4-[[(3Ar,6aS)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]pyridine-3-carboxylic acidIC500.18 [1], 18.7 [2]
2-[[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]-5-fluorobenzoic acidIC500.28 [1], 88.8 [2]
2-[[(3Ar,6aS)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]-5-chlorobenzoic acidIC500.34 [1], 328.8 [2]
2-[[(3Ar,6aS)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]-5-methylsulfonylbenzoic acidIC501.55 [1], 163.1 [2]
2-[[(3Ar,6aS)-5-[2-(trifluoromethyl)phenyl]-3,3a,6,6a-tetrahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]benzoic acidIC500.48 [1], 148.5 [2]
Methyl 2-[(3aR,6aS)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-6-methylpyrimidine-4-carboxylateIC506.3 [1], 100.0 [2]
5-[[(3As,6aR)-5-[2-(trifluoromethyl)phenyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carbonyl]amino]pyridazine-4-carboxylic acidIC500.12 [1], 24.0 [2]
2-[2-(Trifluoromethyl)phenyl]-1-[4-[3-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]ethanoneIC503610.0 [1], 10000.0 [2]
1-[4-(7-Thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(12),2(6),8,10-tetraen-12-yl)piperazin-1-yl]-2-[2-(trifluoromethyl)phenyl]ethanoneIC5060.0 [1], 280.0 [2]
(5-Chloro-2-methoxyphenyl)-[3-methyl-4-(7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(12),2(6),8,10-tetraen-12-yl)piperazin-1-yl]methanoneIC50830.0 [1], 1480.0 [2]
12-[4-[[3-(Trifluoromethyl)phenyl]methyl]piperazin-1-yl]-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(12),2(6),8,10-tetraeneIC5024.0 [1], 600.0 [2]
3-[4-[3,5-Difluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-[1,2,4]triazolo[4,3-a]pyridine-6-carbonitrileIC506.75 [1], 10.49 [2]
[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidin-1-yl]-[5-(oxetan-3-yl)-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]methanoneIC5011.85 [1], 74.13 [2]
1-[3-[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-5-yl]propan-1-oneIC5014.72 [1], 16.28 [2]
1-[3-[4-[3,5-Difluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydropyrazolo[3,4-c]pyridin-6-yl]ethanoneIC506.36 [1], 10.91 [2]
(5-Ethyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-3-yl)-[4-[3-fluoro-2-(trifluoromethyl)phenyl]piperidin-1-yl]methanoneIC508.31 [1], 40.82 [2]
Methyl 3-[4-[3,5-difluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine-5-carboxylateIC5010.12 [1], 24.43 [2]
3-[4-[3-Fluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-[1,2,4]triazolo[4,3-a]pyridine-6-carbonitrileIC505.36 [1], 12.7 [2]
[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidin-1-yl]-[5-(2-methoxyethyl)-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-3-yl]methanoneIC506.96 [1], 49.91 [2]
3-[4-(2-Chloro-3-fluorophenyl)piperidine-1-carbonyl]-[1,2,4]triazolo[4,3-a]pyridine-6-carbonitrileIC503.1 [1], 27.84 [2]
[4-(2-Chloro-3-fluorophenyl)piperidin-1-yl]-(5-ethyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-3-yl)methanoneIC5015.29 [1], 55.27 [2]
[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methanoneIC5010.87 [1], 291.19 [2]
[5-(Cyclopropylmethyl)-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]-[4-[3,4-difluoro-2-(trifluoromethyl)phenyl]piperidin-1-yl]methanoneIC5014.33 [1], 23.97 [2]
[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidin-1-yl]-(5-ethyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-3-yl)methanoneIC507.8 [1], 16.36 [2]
[4-[3-Fluoro-2-(trifluoromethyl)phenyl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-3-yl)methanoneIC5013.33 [1], 44.12 [2]
[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidin-1-yl]-[6-(2,2,2-trifluoroethyl)-1,4,5,7-tetrahydropyrazolo[3,4-c]pyridin-3-yl]methanoneIC5014.99 [1], 62.1 [2]
[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidin-1-yl]-[5-(2,2-dimethylpropyl)-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-3-yl]methanoneIC5014.36 [1], 42.92 [2]
1-[3-[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-5-yl]ethanoneIC501.37 [1], 4.85 [2]
3-[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-N-methyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine-5-carboxamideIC5010.22 [1], 76.56 [2]
[3-[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-5-yl]-pyridin-3-ylmethanoneIC5018.92 [1], 21.76 [2]
[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)methanoneIC5026.85 [1], 200.23 [2]
[3-[4-[3,4-Difluoro-2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-5-yl]-pyridin-4-ylmethanoneIC5011.2 [1], 36.35 [2]
1-[3-[4-(2-Chloro-3-fluorophenyl)piperidine-1-carbonyl]-1,4,5,7-tetrahydropyrazolo[3,4-c]pyridin-6-yl]ethanoneIC504.84 [1], 23.73 [2]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Plasma retinol-binding protein Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/plasma-retinol-binding-protein-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Plasma retinol-binding protein Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/plasma-retinol-binding-protein-inhibitors-ic50-ki.
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