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Phospholipase A2 group V Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
VarespladibIC50124.0 [1], 500.0 [2]
Spla2-X inhibitor 31IC502200.0 [1], 2230.0 [2]
IndoxamIC50100.0 [1]
4-(3,5-Didodecanoyl-2,4,6-trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chromanIC50110.0 [1]
N-Hexadecanoyl-leucineIC501660.0 [1]
DidodecanoylphloroglucinolIC501600.0 [1]
2-(3-(2-Amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)propanoic acidIC5044.0 [1]
(S)-4-Methyl-2-(2-oxohexadecanamido)pentanoic acidIC50440.0 [1]
Me-indoxamIC50270.0 [1]
((3-(2-Amino-1,2-dioxoethyl)-2-methyl-1-(phenylmethyl)-1H-indol-4-yl)oxy)acetic acidIC50800.0 [1]
2-[2-Ethyl-3-oxamoyl-1-(phenylmethyl)benzo[g]indol-4-yl]oxyacetic acidIC5035.0 [1]
2-[4-[2-(Benzenesulfonamido)-2-oxoethoxy]-1-benzyl-2-(2-methylpropyl)indol-3-yl]-2-oxoacetamideIC501600.0 [1]
2-(3-(2-Amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-indol-4-yloxy)acetic acidIC501600.0 [1]
2-(1-Benzyl-2,6-dimethyl-3-oxamoylindol-4-yl)oxyacetic acidIC50800.0 [1]
(2S)-3-Methyl-2-(2-oxohexadecanoylamino)butanoic acidIC501200.0 [1]
(3R)-3-[3-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]phenyl]butanoic acidIC508600.0 [1]
3-[4-(3-Phenylmethoxy-2-tetradecoxypropoxy)phenyl]-4H-1,2,4-oxadiazol-5-oneIC50100000.0 [1]
3-[4-(3-Decoxy-2-tetradecoxypropoxy)phenyl]-4H-1,2,4-oxadiazol-5-oneIC50550.0 [1]
3-[4-[3-(4-Phenylbutoxy)-2-tetradecoxypropoxy]phenyl]-4H-1,2,4-oxadiazol-5-oneIC5022000.0 [1]
3-[4-(3-Benzhydryloxy-2-tetradecoxypropoxy)phenyl]-4H-1,2,4-oxadiazol-5-oneIC502000.0 [1]
3-[4-(2-Tetradecoxy-3-trityloxypropoxy)phenyl]-4H-1,2,4-oxadiazol-5-oneIC50660.0 [1]
4-[[3-[4-[(5-Oxo-4H-1,2,4-oxadiazol-3-yl)methyl]phenoxy]-2-tetradecoxypropoxy]methyl]benzonitrileIC501730.0 [1]
4-[[2-Octadecoxy-3-[4-[(5-oxo-4H-1,2,4-oxadiazol-3-yl)methyl]phenoxy]propoxy]methyl]benzonitrileIC501000.0 [1]
3-[3-(2-Carbamoyl-6-cyclopropylindol-1-yl)phenyl]propanoic acidIC5010000.0 [1]
3-[2-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]pyridin-4-yl]propanoic acidIC50720.0 [1]
3-[3-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]phenyl]-2-methylpropanoic acidIC5010000.0 [1]
(3S)-3-[3-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]phenyl]butanoic acidIC505100.0 [1]
3-[3-[2-Carbamoyl-6-(trifluoromethyl)indol-1-yl]phenyl]propanoic acidIC503700.0 [1]
3-[6-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]pyridin-2-yl]propanoic acidIC502300.0 [1]
3-[6-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]pyridin-2-yl]butanoic acidIC505500.0 [1]
3-[4-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]pyrazol-1-yl]propanoic acidIC502700.0 [1]
3-[4-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]pyridin-2-yl]propanoic acidIC502100.0 [1]
3-[3-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]phenyl]-2-methoxypropanoic acidIC502100.0 [1]
2-[[6-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]pyridin-2-yl]methyl]butanoic acidIC5010000.0 [1]
3-[6-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]pyridin-2-yl]-2-methylpropanoic acidIC5010000.0 [1]
3-[5-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]furan-2-yl]propanoic acidIC505900.0 [1]
3-[6-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]pyridin-2-yl]-2,2-dimethylpropanoic acidIC5010000.0 [1]
3-[2-[2-Carbamoyl-6-(trifluoromethoxy)indol-1-yl]pyridin-4-yl]-2-methylpropanoic acidIC501600.0 [1]
Tert-butyl 2-[(7S)-7-benzyl-5-methyl-1-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-2,6-dioxo-1,3,5-triazepan-3-yl]acetateIC5011000.0 [1]
2-[3-Biphenyl-2-ylmethyl-2-ethyl-8-(2-oxo-propoxy)-indolizin-1-yl]-2-oxo-acetamideIC501600.0 [1]
2-[4-[2-(Benzenesulfonamido)-2-oxoethoxy]-1-benzyl-2-ethylbenzo[g]indol-3-yl]-2-oxoacetamideIC50140.0 [1]
2-[4-[2-(Benzenesulfonamido)-2-oxoethoxy]-1-benzyl-2-(2-methylpropyl)benzo[g]indol-3-yl]-2-oxoacetamideIC501600.0 [1]
2-[1-Benzyl-2-(2-methylpropyl)-3-oxamoylbenzo[g]indol-4-yl]oxyacetic acidIC501600.0 [1]
2-(2-Ethyl-3-(o-phenylbenzyl)-8-(2-oxopropoxy)indolizin-1-yl)-2-oxoacetamideIC501600.0 [1]
2-(3-Biphenyl-2-ylmethyl-2-ethyl-8-methoxy-indolizin-1-yl)-2-oxo-acetamideIC501600.0 [1]
2-Phenyl-1-(2,4,6-trihydroxy-3-methyl-5-phenylacetyl-phenyl)-ethanoneIC501600.0 [1]
(E)-4-[(6S)-6-Benzyl-1-methyl-4,7-dioxo-1,3,5-triazepan-3-yl]but-2-enoic acidIC5012000.0 [1]
Tert-butyl 2-[(6S)-1-methyl-4,7-dioxo-6-propan-2-yl-1,3,5-triazepan-3-yl]acetateIC5012000.0 [1]
(4S,7S)-4,7-Dibenzyl-5-methyl-1,3,5-triazepane-2,6-dioneIC5011000.0 [1]
2-[2-(2-Methylpropyl)-1-oxamoyl-3-[(2-phenylphenyl)methyl]indolizin-8-yl]oxyacetic acidIC501600.0 [1]
1-(3-Dodecanoyl-2,4,6-trihydroxy-5-methyl-phenyl)-dodecan-1-oneIC50530.0 [1]
3,5-(Diacetyl)-2,4,6-trihydroxytolueneIC501600.0 [1]
1-(3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)dodecan-1-oneIC501600.0 [1]
1-(5-Dodecanoyl-2,4-dihydroxy-phenyl)-dodecan-1-oneIC501600.0 [1]
1-(3-Dodecyl-2,4,6-trihydroxyphenyl)dodecan-1-oneIC501600.0 [1]
1-(3-Acetyl-5-dodecyl-2,4,6-trihydroxy-phenyl)-ethanoneIC501600.0 [1]
1-(3-Dodecanoyl-2-hydroxy-5-methyl-phenyl)-dodecan-1-oneIC501600.0 [1]
(R)-4-Methyl-2-(2-oxohexadecanamido)pentanoic acidIC501500.0 [1]
(S)-2-(2-Oxohexadecanamido)-3-phenylpropanoic acidIC501660.0 [1]
2-(3-(2-Amino-2-oxoacetyl)-1-benzyl-2-ethyl-6-methyl-1H-indol-4-yloxy)acetic acidIC50500.0 [1]
Benzenesulfonyl-2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetamideIC50100.0 [1]
Items per page: 1 - 10 of 61
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References

This online tool may be cited as follows

MLA

"Quest Database™ Phospholipase A2 group V Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Nov. 2024, https://www.aatbio.com/data-sets/phospholipase-a2-group-v-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 20). Quest Database™ Phospholipase A2 group V Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phospholipase-a2-group-v-inhibitors-ic50-ki.
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