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Phosphoglycerate kinase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
m-Xylylenediphosphonic AcidIC50200000.0 [1]
m-Xylylenediphosphonic AcidKi120000.0 [1]
[Fluoro-[6-[fluoro(phosphono)methyl]pyridin-2-yl]methyl]phosphonic acidIC5087000.0 [1]
[Fluoro-[6-[fluoro(phosphono)methyl]pyridin-2-yl]methyl]phosphonic acidKi61000.0 [1]
[6-(Phosphonomethyl)pyridin-2-yl]methylphosphonic acidIC50182000.0 [1]
[6-(Phosphonomethyl)pyridin-2-yl]methylphosphonic acidKi80000.0 [1]
[Hydroxy-[3-[hydroxy(phosphono)methyl]phenyl]methyl]phosphonic acidIC50150000.0 [1]
[Hydroxy-[3-[hydroxy(phosphono)methyl]phenyl]methyl]phosphonic acidKi75000.0 [1]
2-(Phosphonomethyl)prop-2-enylphosphonic acidIC5087000.0 [1]
2-(Phosphonomethyl)prop-2-enylphosphonic acidKi61000.0 [1]
[Hydroxy-[6-[hydroxy(phosphono)methyl]pyridin-2-yl]methyl]phosphonic acidIC50163000.0 [1]
[Hydroxy-[6-[hydroxy(phosphono)methyl]pyridin-2-yl]methyl]phosphonic acidKi156000.0 [1]
[Chloro-[6-[chloro(phosphono)methyl]pyridin-2-yl]methyl]phosphonic acidIC501340.0 [1]
[Chloro-[6-[chloro(phosphono)methyl]pyridin-2-yl]methyl]phosphonic acidKi330.0 [1]
[Fluoro-[3-[fluoro(phosphono)methyl]phenyl]methyl]phosphonic acidIC501300.0 [1]
[Fluoro-[3-[fluoro(phosphono)methyl]phenyl]methyl]phosphonic acidKi690.0 [1]
AdenosineIC503000000.0 [1]
N6-CyclopentyladenosineIC503900000.0 [1]
N6-BenzyladenosineIC501000000.0 [1]
2-AminoadenosineIC503500000.0 [1]
(2R,3R,4S,5R)-2-[6-(Cycloheptylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC503900000.0 [1]
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-[6-(pentylamino)purin-9-yl]oxolane-3,4-diolIC503000000.0 [1]
2-[6-Amino-2-(2-phenyl-propylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diolIC50700000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501500000.0 [1]
(2R,3R,4S,5R)-2-[6-Amino-2-(cyclohexylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501500000.0 [1]
(2R,3R,4S,5R)-2-(6-Amino-2-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diolIC501500000.0 [1]
[4-(Phosphonomethyl)phenyl]methylphosphonic AcidIC50193000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-(3-phenylpropylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501800000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-(benzylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC503500000.0 [1]
(3R,4S,5R)-2-[6-(2-Aminoethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC502500000.0 [1]
(3R,4S,5R)-2-[2,6-Bis(2-phenylethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC5030000.0 [1]
(2R,3R,4S,5R)-2-[6-Amino-2-(propylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501500000.0 [1]
[(3-Phosphonophenyl)hydroxymethyl]phosphonic acidIC50102000.0 [1]
[[4-(Phosphonomethyl)phenyl]fluoromethyl]phosphonic acidIC5010700.0 [1]
[[3-(Phosphonodifluoromethyl)phenyl]difluoromethyl]phosphonic acidIC50960.0 [1]
[[4-(Phosphonomethyl)phenyl]chloromethyl]phosphonic acidIC509400.0 [1]
[Fluoro-[4-[fluoro(phosphono)methyl]phenyl]methyl]phosphonic acidIC501150.0 [1]
[4-[Hydroxy(phosphono)methyl]phenyl]methylphosphonic acidIC5089000.0 [1]
[[3-(Phosphonomethyl)phenyl]fluoromethyl]phosphonic acidIC508350.0 [1]
[2,4-Dimethyl-5-(phosphonomethyl)phenyl]methylphosphonic acidIC5073000.0 [1]
[Hydroxy-[4-[hydroxy(phosphono)methyl]phenyl]methyl]phosphonic acidIC50181000.0 [1]
[(3-Phosphonophenyl)methyl]phosphonic acidIC50138000.0 [1]
[(3-Phosphonophenyl)difluoromethyl]phosphonic acidIC501000.0 [1]
[Chloro-[3-[chloro(phosphono)methyl]phenyl]methyl]phosphonic acidIC501000.0 [1]
[(3-Phosphonophenyl)fluoromethyl]phosphonic acidIC5016000.0 [1]
[3-Methyl-5-(phosphonomethyl)phenyl]methylphosphonic acidIC5099000.0 [1]
[[3-(Phosphonomethyl)phenyl]difluoromethyl]phosphonic acidIC501800.0 [1]
[[4-(Phosphonodifluoromethyl)phenyl]difluoromethyl]phosphonic acidIC50980.0 [1]
[[6-(Phosphonodifluoromethyl)-2-pyridinyl]difluoromethyl]phosphonic acidIC501170.0 [1]
[3-[Hydroxy(phosphono)methyl]phenyl]methylphosphonic acidIC5068800.0 [1]
[2-Fluoro-3-(phosphonomethyl)phenyl]methylphosphonic acidIC50147000.0 [1]
[Chloro-[4-[chloro(phosphono)methyl]phenyl]methyl]phosphonic acidIC501080.0 [1]
[[3-[Difluoro(phosphono)methyl]-5-methylphenyl]-difluoromethyl]phosphonic acidIC50880.0 [1]
[[3-(Phosphonomethyl)phenyl]chloromethyl]phosphonic acidIC508000.0 [1]
[(3-Phosphonophenyl)chloromethyl]phosphonic acidIC5017000.0 [1]
[[4-(Phosphonomethyl)phenyl]difluoromethyl]phosphonic acidIC501980.0 [1]
[2,4,6-Trimethyl-3-(phosphonomethyl)phenyl]methylphosphonic acidIC5078000.0 [1]
o-Xylylenediphosphonic AcidIC50107000.0 [1]
(2R,3R,4S,5R)-2-[6-Amino-2-[(2-hydroxy-2-phenylethyl)amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501400000.0 [1]
[Dichloro-[3-[dichloro(phosphono)methyl]phenyl]methyl]phosphonic acidIC503600.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(4-hydroxy-3-methoxyphenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501500000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(3-methoxyphenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501900000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-[(2-chlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC502000000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(cycloheptylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC502500000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(3-aminopropylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC504000000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(2-methoxyphenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501800000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(benzylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50600000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[5-[[2-amino-9-[(3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]pentylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501000000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-(butylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501500000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(cyclohexylmethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC502500000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-[(4-methoxyphenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501000000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(3-phenylpropylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC504000000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(4-hydroxyphenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50130000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(pentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC502000000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(3-chlorophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501200000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(2-phenylpropylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC502900000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(ethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC503500000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(1-phenylethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC502900000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(2-chlorophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501900000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-[(3-methylphenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501500000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(furan-2-ylmethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501500000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-[2-(2,4-dichlorophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50600000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(4-methylphenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50200000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-(cycloheptylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC503000000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-[(2-methoxyphenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501400000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(4-methoxyphenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501500000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(prop-2-ynylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501500000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(3-hydroxyphenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50250000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50250000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-[(3-chlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50800000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[2-(3,4-dihydroxyphenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50250000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-[2-(4-hydroxyphenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50500000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(2-phenylethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50200000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(naphthalen-1-ylmethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC501900000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-(2-phenylpropylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC503500000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-(oxolan-2-ylmethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50800000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50500000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-[4-[[2-amino-9-[(3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50750000.0 [1]
(3R,4S,5R)-2-[2-Amino-6-(butylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC50900000.0 [1]
(3R,4S,5R)-2-[6-Amino-2-[2-(2-chlorophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolIC502200000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Phosphoglycerate kinase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/phosphoglycerate-kinase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Phosphoglycerate kinase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phosphoglycerate-kinase-inhibitors-ic50-ki.
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