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Phosphoglycerate kinase 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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▼
Standard Values (in nM)
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▼
6-Chloro-2-N,3-N-diethyl-7-methoxyquinoxaline-2,3-diamineIC509.0 [1]
7-Chloro-2,3-bis(ethylamino)quinoxalin-6-olIC50366.0 [1]
2-N-Ethyl-6,7-dimethoxy-3-N-(pyridin-3-ylmethyl)quinoxaline-2,3-diamineIC50710.0 [1]
2-N-Ethyl-6,7-dimethoxy-3-N-(pyridin-4-ylmethyl)quinoxaline-2,3-diamineIC502010.0 [1]
2-N-Ethyl-6,7-dimethoxy-3-N-(pyridin-2-ylmethyl)quinoxaline-2,3-diamineIC501280.0 [1]
2-N-Ethyl-6,7-dimethoxy-3-N-(3-pyrrolidin-1-ylpropyl)quinoxaline-2,3-diamineIC504360.0 [1]
1-[3-[[3-(Ethylamino)-6,7-dimethoxyquinoxalin-2-yl]amino]propyl]pyrrolidin-2-oneIC501810.0 [1]
2-N-Ethyl-6,7-dimethoxy-3-N-(2-pyridin-2-ylethyl)quinoxaline-2,3-diamineIC50840.0 [1]
6,7-Dimethoxy-3-pyridin-4-yl-N-(pyridin-3-ylmethyl)quinoxalin-2-amineIC507590.0 [1]
3,6-Dichloro-N-ethyl-7-methoxyquinoxalin-2-amineIC501180.0 [1]
6-Chloro-2-N-ethyl-7-methoxy-3-N-(pyridin-3-ylmethyl)quinoxaline-2,3-diamineIC50129.0 [1]
N-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]acetamideIC504140.0 [1]
7-Chloro-2,3-bis(ethylamino)quinoxaline-6-carbonitrileIC5038.0 [1]
7-Chloro-2-(ethylamino)-3-(pyridin-3-ylmethylamino)quinoxaline-6-carbonitrileIC5015.0 [1]
7-Chloro-2-(ethylamino)-3-[2-(4-methylpiperazin-1-yl)ethylamino]quinoxaline-6-carbonitrileIC5071.0 [1]
6-Chloro-2-N-ethyl-7-methoxy-3-N-[2-(4-methylpiperazin-1-yl)ethyl]quinoxaline-2,3-diamineIC50173.0 [1]
6-Chloro-2-N-ethyl-7-methoxy-3-N-[3-(4-methylpiperazin-1-yl)propyl]quinoxaline-2,3-diamineIC50195.0 [1]
6-Chloro-2-N-ethyl-7-methoxy-3-N-(3-pyrrolidin-1-ylpropyl)quinoxaline-2,3-diamineIC50252.0 [1]
6-Chloro-3-N-[5-(diethylamino)pentan-2-yl]-2-N-ethyl-7-methoxyquinoxaline-2,3-diamineIC50515.0 [1]
4-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]but-3-yn-1-olIC505.0 [1]
5-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]pent-4-yn-2-olIC50122.0 [1]
5-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]pent-4-yn-1-olIC5042.0 [1]
2-[4-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]but-3-ynyl]isoindole-1,3-dioneIC503160.0 [1]
6-(4-Aminobut-1-ynyl)-7-chloro-2-N,3-N-diethylquinoxaline-2,3-diamineIC501050.0 [1]
6-Chloro-3-(3-chlorophenyl)-N-ethyl-7-methoxyquinoxalin-2-amineIC502100.0 [1]
6-Chloro-3-(4-chlorophenyl)-N-ethyl-7-methoxyquinoxalin-2-amineIC501900.0 [1]
3-(1,3-Benzodioxol-5-yl)-6-chloro-N-ethyl-7-methoxyquinoxalin-2-amineIC502300.0 [1]
6-Chloro-N-ethyl-7-methoxy-3-thiophen-2-ylquinoxalin-2-amineIC50190.0 [1]
3-(1-Benzofuran-2-yl)-6-chloro-N-ethyl-7-methoxyquinoxalin-2-amineIC501400.0 [1]
1-[5-[7-Chloro-3-(ethylamino)-6-methoxyquinoxalin-2-yl]thiophen-2-yl]ethanoneIC501100.0 [1]
3-(1-Benzothiophen-3-yl)-6-chloro-N-ethyl-7-methoxyquinoxalin-2-amineIC502000.0 [1]
3-(1-Benzothiophen-2-yl)-6-chloro-N-ethyl-7-methoxyquinoxalin-2-amineIC5078.0 [1]
3-[7-Chloro-3-(ethylamino)-6-methoxyquinoxalin-2-yl]benzamideIC50240.0 [1]
6-Chloro-N-ethyl-3-(1H-indol-4-yl)-7-methoxyquinoxalin-2-amineIC504400.0 [1]
6-Chloro-N-ethyl-3-isoquinolin-4-yl-7-methoxyquinoxalin-2-amineIC501500.0 [1]
6-Chloro-N-ethyl-7-methoxy-3-quinolin-5-ylquinoxalin-2-amineIC501400.0 [1]
6-Chloro-N-ethyl-7-methoxy-3-quinolin-3-ylquinoxalin-2-amineIC504600.0 [1]
6-Chloro-N-ethyl-7-methoxy-3-(1H-pyrazol-4-yl)quinoxalin-2-amineIC5075.0 [1]
6-Chloro-N-ethyl-7-methoxy-3-(1-methylpyrazol-4-yl)quinoxalin-2-amineIC5066.0 [1]
6-Chloro-N-ethyl-7-methoxy-3-(1-methylindol-5-yl)quinoxalin-2-amineIC50220.0 [1]
6-[7-Chloro-3-(ethylamino)-6-methoxyquinoxalin-2-yl]chromen-4-oneIC501600.0 [1]
Tert-butyl 4-[5-[7-chloro-3-(ethylamino)-6-methoxyquinoxalin-2-yl]pyridin-2-yl]piperazine-1-carboxylateIC501700.0 [1]
6-Chloro-N-ethyl-7-methoxy-3-(2-phenylphenyl)quinoxalin-2-amineIC502000.0 [1]
5-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]pent-4-ynenitrileIC5054.0 [1]
3-[7-Chloro-3-(ethylamino)-6-methoxyquinoxalin-2-yl]-N-(furan-2-ylmethyl)benzamideIC50210.0 [1]
N-Benzyl-3-[7-chloro-3-(ethylamino)-6-methoxyquinoxalin-2-yl]benzamideIC50550.0 [1]
3-(1-Benzylpyrazol-4-yl)-6-chloro-N-ethyl-7-methoxyquinoxalin-2-amineIC5091.0 [1]
5-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]-4-oxopentanoic acidIC505830.0 [1]
4-[7-Chloro-2,3-bis[2-(4-methylpiperazin-1-yl)ethylamino]quinoxalin-6-yl]but-3-yn-1-olIC5036.0 [1]
4-[7-Chloro-3-(ethylamino)-2-[3-(4-methylpiperazin-1-yl)propylamino]quinoxalin-6-yl]but-3-yn-1-olIC5016.0 [1]
2-[3-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]-1,2,4-oxadiazol-5-yl]ethanolIC50596.0 [1]
N-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]-3-hydroxypropanamideIC501090.0 [1]
4-[7-Chloro-3-(ethylamino)-2-(4-hydroxybut-1-ynyl)quinoxalin-6-yl]but-3-yn-1-olIC50665.0 [1]
4-[2,7-Dichloro-3-(ethylamino)quinoxalin-6-yl]but-3-yn-1-olIC5041.0 [1]
7-Chloro-2-[2-(4-methylpiperazin-1-yl)ethylamino]-3-pyridin-2-ylquinoxaline-6-carbonitrileIC50346.0 [1]
4-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]but-3-yn-2-olIC50125.0 [1]
4-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]-2-methylbut-3-yn-2-olIC502690.0 [1]
1-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]-3-methylpent-1-yn-3-olIC504810.0 [1]
6-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]hex-5-yn-1-olIC50385.0 [1]
3-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]prop-2-ynyl propanoateIC50257.0 [1]
3-[2-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]ethynyl]phenolIC505700.0 [1]
2-[3-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]prop-2-ynoxy]ethanolIC50103.0 [1]
3-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]prop-2-yn-1-olIC501.0 [1]
1-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]hex-1-yn-3-olIC502000.0 [1]
Methyl 3-[7-chloro-2,3-bis(ethylamino)quinoxalin-6-yl]prop-2-ynoateIC50633.0 [1]
3-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]prop-2-ynamideIC50556.0 [1]
3-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]prop-2-ynylureaIC50393.0 [1]
6-Chloro-N-ethyl-7-methoxy-3-naphthalen-1-ylquinoxalin-2-amineIC5010000.0 [1]
Methyl 5-[7-chloro-2,3-bis(ethylamino)quinoxalin-6-yl]-4-oxopentanoateIC509000.0 [1]
6,7-Dimethoxy-3-pyridin-4-yl-N-(3-pyrrolidin-1-ylpropyl)quinoxalin-2-amineIC5010000.0 [1]
2-[1-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]azetidin-3-yl]ethanolIC5010000.0 [1]
N-Ethyl-6,7-dimethoxy-3-pyridin-4-ylquinoxalin-2-amineIC506660.0 [1]
3-Chloro-N-ethyl-6,7-dimethoxyquinoxalin-2-amineIC506320.0 [1]
2-N,3-N-Diethyl-6,7-dimethoxyquinoxaline-2,3-diamineIC5050000.0 [1]
3-Bromo-N-ethyl-6,7-dimethoxyquinoxalin-2-amineIC504640.0 [1]
3-Chloro-6,7-dimethoxy-N-methylquinoxalin-2-amineIC5024000.0 [1]
3-Bromo-6,7-dimethoxy-N-[2-(4-methylpiperazin-1-yl)ethyl]quinoxalin-2-amineIC5016430.0 [1]
6-Chloro-2-N,3-N-diethyl-7-(trifluoromethoxy)quinoxaline-2,3-diamineIC501170.0 [1]
2-N-Ethyl-6,7-dimethoxy-3-N-(2-pyridin-4-ylethyl)quinoxaline-2,3-diamineIC50741.0 [1]
6-[7-Chloro-2,3-bis(ethylamino)quinoxalin-6-yl]hex-5-ynenitrileIC50570.0 [1]
6-Chloro-2-N,3-N-diethyl-7-hex-1-ynylquinoxaline-2,3-diamineIC50884.0 [1]
6-Chloro-7-(2-cyclopropylethynyl)-2-N,3-N-diethylquinoxaline-2,3-diamineIC5019.0 [1]
3-N-Ethyl-6,7-dimethoxy-2-N-methylquinoxaline-2,3-diamineIC502530.0 [1]
6-Chloro-2-N,3-N-diethyl-7-[2-(furan-3-yl)ethynyl]quinoxaline-2,3-diamineIC501030.0 [1]
7-Chloro-2-N,2-N-diethylquinoxaline-2,3,6-triamineIC5010000.0 [1]
6-Chloro-2-N,3-N-diethyl-7-nitroquinoxaline-2,3-diamineIC5098.0 [1]
6-Chloro-2-N,3-N-diethyl-7-(3-methoxyprop-1-ynyl)quinoxaline-2,3-diamineIC5066.0 [1]
4-[7-Chloro-3-(ethylamino)-2-[2-(4-methylpiperazin-1-yl)ethylamino]quinoxalin-6-yl]but-3-yn-1-olIC508.0 [1]
6-But-1-ynyl-7-chloro-2-N,3-N-diethylquinoxaline-2,3-diamineIC50270.0 [1]
6-Chloro-2-N,3-N-diethyl-7-prop-2-ynoxyquinoxaline-2,3-diamineIC50320.0 [1]
6-Chloro-2-N,3-N-diethyl-7-ethynylquinoxaline-2,3-diamineIC5012.0 [1]
Items per page: 1 - 10 of 91
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References

This online tool may be cited as follows

MLA

"Quest Database™ Phosphoglycerate kinase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/phosphoglycerate-kinase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Phosphoglycerate kinase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phosphoglycerate-kinase-1-inhibitors-ic50-ki.
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