Phosphodiesterase 8 Inhibitors (IC50, Ki)

Name: Phosphodiesterase 8 Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Sildenafil	IC50	10000.0 ^[1]
	Tadalafil	IC50	10000.0 ^[1]
	Vardenafil	IC50	10000.0 ^[1]
	4-(3-(1-Acetylpiperidine-4-yl)pyrazine-2-yloxy)phenyl(1H-benzoimidazole-2-yl)methanone	IC50	30000.0 ^[1]
	4-[(3-Chloro-4-methoxyphenyl)methylamino]-8-cyclopropyl-3-(hydroxymethyl)quinoline-6-carbonitrile	IC50	10000.0 ^[1]
	6-Methoxy-3,8-Dimethyl-4-(Piperazin-1-Yl)-1h-Pyrazolo[3,4-B]quinoline	Ki	770.0 ^[1]
	6-Methoxy-3,8-dimethyl-N-(oxan-4-yl)-2H-pyrazolo[3,4-b]quinolin-4-amine	Ki	4793.0 ^[1]
	4-[(3-Chloro-4-methoxyphenyl)methylamino]-8-(dimethylamino)-3-(hydroxymethyl)quinoline-6-carbonitrile	IC50	10000.0 ^[1]
	1-(3-Pyridyl)-8,9-dimethoxy-5,6-dihydroimidazo[5,1-a]isoquinoline	Ki	4274.0 ^[1]
	5-(8,9-Dimethoxy-3-methyl-5,6-dihydroimidazo[5,1-a]isoquinolin-1-yl)-1,3-thiazole	Ki	7100.0 ^[1]
	1-(3-Pyridyl)-8,9-dimethoxy-3-methyl-5,6-dihydroimidazo[5,1-a]isoquinoline	Ki	7950.0 ^[1]
	N-Tert-butyl-5-(8,9-dimethoxy-5,6-dihydroimidazo[5,1-a]isoquinolin-1-yl)-N-methyl-1,3-thiazole-2-carboxamide	Ki	2000.0 ^[1]
	8,9-Dimethoxy-1-(1,3-Thiazol-5-Yl)-5,6-Dihydroimidazo[5,1-A]isoquinoline	Ki	2000.0 ^[1]

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References

MLA	"Quest Database™ Phosphodiesterase 8 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Nov. 2024, https://www.aatbio.com/data-sets/phosphodiesterase-8-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, November 20). Quest Database™ Phosphodiesterase 8 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phosphodiesterase-8-inhibitors-ic50-ki.
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