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Phosphodiesterase 7 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
SildenafilIC5010000.0 [1]
TadalafilIC5010000.0 [1]
VardenafilIC501900.0 [1], 10000.0 [2]
DipyridamoleKi600.0 [1]
3-Isobutyl-1-methylxanthineKi4000.0 [1]
3-Phenyl-1H-quinazoline-2,4-dithioneIC501040.0 [1]
4-(3-(1-Acetylpiperidine-4-yl)pyrazine-2-yloxy)phenyl(1H-benzoimidazole-2-yl)methanoneIC5030000.0 [1]
1-[(3,4-Dichlorophenyl)-methyl]-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxideIC508000.0 [1]
2-Propan-2-yl-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC50770.0 [1]
2-Methyl-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC5011000.0 [1]
4-[(3-Chloro-4-methoxyphenyl)methylamino]-8-cyclopropyl-3-(hydroxymethyl)quinoline-6-carbonitrileIC5010000.0 [1]
(3,4,5-Trimethoxyphenyl)methyl 5-phenylfuran-2-carboxylateIC505170.0 [1]
(7R)-7-Benzyl-2-bromo-5-ethyl-3-[(4-hydroxyphenyl)methyl]-7,8-dihydroimidazo[2,1-b]purin-4-oneIC5010000.0 [1]
2-Amino-8-bromo-9-(tetralin-1-yl)-1,6-dihydro-9H-purine-6-oneIC504880.0 [1]
2-Amino-8-bromo-9-(8-bromotetralin-1-yl)-1,6-dihydro-9H-purine-6-oneIC501310.0 [1]
2-Amino-8-bromo-9-(7-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-1H-purin-6-oneIC504220.0 [1]
2-Amino-8-bromo-9-(7-nitro-1,2,3,4-tetrahydronaphthalen-1-yl)-1H-purin-6-oneIC502310.0 [1]
6-Methoxy-3,8-Dimethyl-4-(Piperazin-1-Yl)-1h-Pyrazolo[3,4-B]quinolineKi770.0 [1]
6-Methoxy-3,8-dimethyl-N-(oxan-4-yl)-2H-pyrazolo[3,4-b]quinolin-4-amineKi4793.0 [1]
4-[(3-Chloro-4-methoxyphenyl)methylamino]-8-(dimethylamino)-3-(hydroxymethyl)quinoline-6-carbonitrileIC5010000.0 [1]
2-Benzylsulfanyl-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC507100.0 [1]
2-[(4-Fluorophenyl)methylsulfanyl]-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC506800.0 [1]
2-[(4-Nitrophenyl)methylsulfanyl]-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC504900.0 [1]
2-[(3-Methoxyphenyl)methylsulfanyl]-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC503300.0 [1]
4-[[4-[4-(2H-Tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC507200.0 [1]
2-Methyl-4-[[4-[3-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC502500.0 [1]
2-Methyl-4-[[4-[4-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC508000.0 [1]
4-[[4-[2-(2H-Tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]-2-(trichloromethyl)quinazolineIC502600.0 [1]
2-Propan-2-yl-4-[[4-[3-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC50890.0 [1]
2-(4-Chlorophenyl)-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC5012000.0 [1]
5,7-Dibromo-2-(2-phenylethyl)-4-[[4-[3-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC50100000.0 [1]
6,7,8-Trimethoxy-2-(2-phenylethyl)-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC503600.0 [1]
2-[4-(Quinazolin-4-ylsulfanylmethyl)phenyl]benzonitrileIC50100000.0 [1]
2-[4-[(2-Methylquinazolin-4-yl)sulfanylmethyl]phenyl]benzonitrileIC50100000.0 [1]
2-[4-[[2-(Trichloromethyl)quinazolin-4-yl]sulfanylmethyl]phenyl]benzonitrileIC50100000.0 [1]
2-[4-[(2-Propan-2-ylquinazolin-4-yl)sulfanylmethyl]phenyl]benzonitrileIC50100000.0 [1]
2-[4-[[2-[(4-Fluorophenyl)methylsulfanyl]quinazolin-4-yl]sulfanylmethyl]phenyl]benzonitrileIC50100000.0 [1]
2-[4-[[2-[(4-Nitrophenyl)methylsulfanyl]quinazolin-4-yl]sulfanylmethyl]phenyl]benzonitrileIC50100000.0 [1]
Methyl 2-[4-[(2-propan-2-ylquinazolin-4-yl)sulfanylmethyl]phenyl]benzoateIC50100000.0 [1]
Methyl 3-[4-[(2-propan-2-ylquinazolin-4-yl)sulfanylmethyl]phenyl]benzoateIC50100000.0 [1]
Methyl 4-[4-[(2-propan-2-ylquinazolin-4-yl)sulfanylmethyl]phenyl]benzoateIC5033000.0 [1]
2-[4-[(2-Propan-2-ylquinazolin-4-yl)sulfanylmethyl]phenyl]benzoic acidIC5044000.0 [1]
3-[4-[(2-Propan-2-ylquinazolin-4-yl)sulfanylmethyl]phenyl]benzoic acidIC50850.0 [1]
4-[4-[(2-Propan-2-ylquinazolin-4-yl)sulfanylmethyl]phenyl]benzoic acidIC50930.0 [1]
4-[[4-[3-(2H-Tetrazol-5-yl)phenyl]phenyl]methylsulfanyl]quinazolineIC508200.0 [1]
2-[(2,3-Diphenyl-1,2,4-thiadiazol-5-ylidene)amino]ethanolIC501110.0 [1]
Items per page: 1 - 10 of 46
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References

This online tool may be cited as follows

MLA

"Quest Database™ Phosphodiesterase 7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/phosphodiesterase-7-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Phosphodiesterase 7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phosphodiesterase-7-inhibitors-ic50-ki.
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