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Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneIC502100.0 [1], 10400.0 [2]
PictilisibIC50590.0 [1], 670.0 [2], 900.9 [3]
IdelalisibIC501000.0 [1], 10000.0 [2]
3-(4-Morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol;hydrochlorideIC50220.0 [1]
4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholineIC50180.0 [1]
N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamideIC50140.0 [1], 14000.0 [2]
N-(7,8-Dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamideIC5064.0 [1]
N-[2-[3-(Benzenesulfonamido)phenyl]-4-morpholin-4-ylquinazolin-6-yl]acetamideIC50630.0 [1]
pi-103 (Hydrochloride)IC5010.0 [1]
DactolisibIC5044.0 [1]
PI-103IC5026.0 [1]
Torin 1IC50549.0 [1]
ApitolisibIC50794.0 [1]
Torin 2IC5024.5 [1]
TaselisibIC50292.0 [1]
PIK-75 HydrochlorideIC50100.0 [1]
CID 72709209IC5010000.0 [1]
5-(7-(Methylsulfonyl)-2-morpholino-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrimidin-2-amineIC505300.0 [1]
(S)-2-(2-(2-Methylindolin-1-yl)-2-oxoethyl)-6-morpholinopyrimidin-4(3H)-oneIC501000.0 [1]
4-[2-[(6-Methoxypyridin-3-yl)amino]-5-[(4-methylsulfonylpiperazin-1-yl)methyl]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amineIC5029.0 [1]
Chembl4126156IC5031.62 [1]
(2S)-N1-[5-(2-Tert-butyl-4-thiazolyl)-4-methyl-2-thiazolyl]pyrrolidine-1,2-dicarboxamideIC50462.0 [1]
Vps34-IN-1IC5010000.0 [1]
Chmfl-PI3KD-317IC50882.3 [1]
N-[4-Morpholin-4-yl-2-[3-(naphthalen-1-ylsulfonylamino)phenyl]quinazolin-6-yl]acetamideIC50530.0 [1]
N-[3-[[3-(2,5-Dimethoxyanilino)pyrazin-2-yl]sulfamoyl]phenyl]acetamideIC5044800.0 [1]
3-[[3-(2,5-Dimethoxyanilino)pyrazin-2-yl]sulfamoyl]benzoic acidIC5061200.0 [1]
N-[3-(2-Chloro-5-hydroxyanilino)pyrazin-2-yl]benzenesulfonamideIC502710.0 [1]
1-[4-(3-Methyl-2-oxo-8-quinolin-3-ylimidazo[4,5-c]quinolin-1-yl)phenyl]cyclopropane-1-carbonitrileIC5044.0 [1]
8-Ethyl-11-(3-methoxyphenyl)-13-morpholin-4-yl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thioneIC5020840.0 [1]
8-Ethyl-11-(4-methoxyphenyl)-13-morpholin-4-yl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thioneIC5013560.0 [1]
11-(3-Methoxyphenyl)-13-morpholin-4-yl-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thioneIC5014560.0 [1]
11-(4-Methoxyphenyl)-13-morpholin-4-yl-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thioneIC5085540.0 [1]
13-Morpholin-4-yl-11-(morpholin-4-ylmethyl)-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thioneIC5078780.0 [1]
13-Morpholin-4-yl-11-(1-morpholin-4-ylethyl)-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thioneIC5028640.0 [1]
8-Ethyl-11-(3-hydroxyphenyl)-13-morpholin-4-yl-7-sulfanylidene-6,8,10-triazatricyclo[7.4.0.02,6]trideca-1(9),10,12-triene-12-carbonitrileIC5081560.0 [1]
8-Ethyl-11-(3-methoxyphenyl)-13-morpholin-4-yl-7-sulfanylidene-6,8,10-triazatricyclo[7.4.0.02,6]trideca-1(9),10,12-triene-12-carbonitrileIC509760.0 [1]
8-Ethyl-11-(4-methoxyphenyl)-13-morpholin-4-yl-7-sulfanylidene-6,8,10-triazatricyclo[7.4.0.02,6]trideca-1(9),10,12-triene-12-carbonitrileIC508460.0 [1]
8-Ethyl-11-(3-hydroxy-4-methoxyphenyl)-13-morpholin-4-yl-7-sulfanylidene-6,8,10-triazatricyclo[7.4.0.02,6]trideca-1(9),10,12-triene-12-carbonitrileIC508560.0 [1]
11-(3,4-Dimethoxyphenyl)-8-ethyl-13-morpholin-4-yl-7-sulfanylidene-6,8,10-triazatricyclo[7.4.0.02,6]trideca-1(9),10,12-triene-12-carbonitrileIC508750.0 [1]
N-[4-Morpholin-4-yl-2-[3-(naphthalen-2-ylsulfonylamino)phenyl]quinazolin-6-yl]acetamideIC50530.0 [1]
4-[(3-Chloro-4-fluorophenyl)methyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-oneIC50370.0 [1]
3-(6-Morpholin-4-yl-8-oxa-5,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-4-yl)phenolIC5026.0 [1]
11-(Morpholin-4-ylmethyl)-8-phenyl-7-sulfanylidene-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(9),10-dien-13-oneIC504430.0 [1]
11-(1-Morpholin-4-ylethyl)-8-phenyl-7-sulfanylidene-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(9),10-dien-13-oneIC509450.0 [1]
8-Ethyl-11-(morpholin-4-ylmethyl)-7-sulfanylidene-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(9),10-dien-13-oneIC505250.0 [1]
8-Ethyl-11-(1-morpholin-4-ylethyl)-7-sulfanylidene-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(9),10-dien-13-oneIC502670.0 [1]
(2S)-2-Amino-N-[5-[6-chloro-5-[(4-methylphenyl)sulfonylamino]pyridin-3-yl]-4-methyl-1,3-thiazol-2-yl]-3-methylbutanamideIC50247.9 [1]
(2S)-2-Amino-N-[5-[6-chloro-5-[(2-methylphenyl)sulfonylamino]pyridin-3-yl]-4-methyl-1,3-thiazol-2-yl]-3-methylbutanamideIC501096.0 [1]
4-[(3-Chloro-4-fluorophenyl)methyl]-6-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-oneIC50370.0 [1]
4-(6-Chloroimidazo[1,2-a]pyridin-3-yl)-2-(2-methyl-5-nitrophenyl)sulfonyl-1,3-thiazole;hydrochlorideIC50100.0 [1]
SureCN6875931IC50437.0 [1]
(2S)-N-[5-(6-Aminopyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]-4,4,4-trifluoro-2-methylbutanamideIC508900.0 [1]
N-[5-(6-Aminopyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]-4,4,4-trifluoro-2,2-dimethylbutanamideIC505600.0 [1]
Items per page: 1 - 10 of 54
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References

This online tool may be cited as follows

MLA

"Quest Database™ Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/phosphatidylinositol-4-phosphate-3-kinase-c2-domain-containing-beta-polypeptide-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phosphatidylinositol-4-phosphate-3-kinase-c2-domain-containing-beta-polypeptide-inhibitors-ic50-ki.
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