Phosphatidylinositol 4-kinase, PI4K Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Adenosine	IC50	30300.0 [1]
	Adenosine	Ki	19200.0 [1]
	Adenosine-5'-diphosphate	IC50	145300.0 [1]
	Adenosine-5'-diphosphate	Ki	100100.0 [1]
	2-Aminopurine	IC50	341600.0 [1]
	2-Aminopurine	Ki	235400.0 [1]
	6-Benzylaminopurine	IC50	240400.0 [1]
	6-Benzylaminopurine	Ki	199000.0 [1]
	9-(Tetrahydrofuran-2-yl)-9h-purin-6-amine	IC50	28200.0 [1]
	9-(Tetrahydrofuran-2-yl)-9h-purin-6-amine	Ki	21200.0 [1]
	6-Dimethylaminopurine	IC50	218000.0 [1]
	6-Dimethylaminopurine	Ki	150200.0 [1]
	1H-Purine-2,6-diamine, sulfate	IC50	146800.0 [1]
	1H-Purine-2,6-diamine, sulfate	Ki	101200.0 [1]
	9-Methyladenine	IC50	161000.0 [1]
	9-Methyladenine	Ki	110900.0 [1]
	1H-Pyrazolo[3,4-d]pyrimidin-4-amine	IC50	144900.0 [1]
	1H-Pyrazolo[3,4-d]pyrimidin-4-amine	Ki	99900.0 [1]
	9-Ethyladenine	IC50	32400.0 [1]
	9-Ethyladenine	Ki	25500.0 [1]
	9-Benzyladenine	IC50	84400.0 [1]
	9-Benzyladenine	Ki	57900.0 [1]
	Quinazolin-4-amine	IC50	91700.0 [1]
	Quinazolin-4-amine	Ki	63400.0 [1]
	1-Phenyl-1h-pyrazolo[3,4-d]pyrimidin-4-amine	IC50	16100.0 [1]
	1-Phenyl-1h-pyrazolo[3,4-d]pyrimidin-4-amine	Ki	11000.0 [1]
	9-Cyclopentyladenine	IC50	8700.0 [1]
	9-Cyclopentyladenine	Ki	6000.0 [1]
	2',3'-O-Isopropylideneadenosine	IC50	12100.0 [1]
	2',3'-O-Isopropylideneadenosine	Ki	8400.0 [1]
	Adenine hydrochloride	IC50	182600.0 [1]
	Adenine hydrochloride	Ki	85800.0 [1]
	2,6-Diamino-8-phenylpurine	IC50	199500.0 [1]
	2,6-Diamino-8-phenylpurine	Ki	137700.0 [1]
	8-Phenyl-7H-purin-6-amine	IC50	48800.0 [1]
	8-Phenyl-7H-purin-6-amine	Ki	33600.0 [1]
	9-Cyclohexyladenine	IC50	6000.0 [1]
	9-Cyclohexyladenine	Ki	3700.0 [1]
	9-Phenylpurin-6-amine	IC50	15400.0 [1]
	9-Phenylpurin-6-amine	Ki	10300.0 [1]
	8-Methyl-7H-purin-6-amine	IC50	195400.0 [1]
	8-Methyl-7H-purin-6-amine	Ki	134300.0 [1]
	9-(2-Methylphenyl)adenine	IC50	23600.0 [1]
	9-(2-Methylphenyl)adenine	Ki	16500.0 [1]
	9-Cycloheptylpurin-6-amine	IC50	7200.0 [1]
	9-Cycloheptylpurin-6-amine	Ki	5000.0 [1]
	9-Methyl-8-phenylpurine-6-ylamine	IC50	34900.0 [1]
	9-Methyl-8-phenylpurine-6-ylamine	Ki	24100.0 [1]
	9-Isopropyl-9H-purin-6-amine	IC50	14900.0 [1]
	9-Isopropyl-9H-purin-6-amine	Ki	10300.0 [1]
	6-Amino-9-(1-naphthalenyl)-9H-purine	IC50	78800.0 [1]
	6-Amino-9-(1-naphthalenyl)-9H-purine	Ki	54400.0 [1]
	(3R,4S,5S)-2-(6-Aminopurin-9-yl)-5-(iodomethyl)oxolane-3,4-diol	IC50	23100.0 [1]
	(3R,4S,5S)-2-(6-Aminopurin-9-yl)-5-(iodomethyl)oxolane-3,4-diol	Ki	15900.0 [1]
	N9-(4-Methoxyphenyl)adenine	IC50	21900.0 [1]
	N9-(4-Methoxyphenyl)adenine	Ki	15200.0 [1]
	6-Amino-8-(1-naphthalenyl)-9H-purine	IC50	129800.0 [1]
	6-Amino-8-(1-naphthalenyl)-9H-purine	Ki	89500.0 [1]
	9-(4-Chlorophenyl)-9h-purin-6-amine	IC50	41100.0 [1]
	9-(4-Chlorophenyl)-9h-purin-6-amine	Ki	28200.0 [1]
	6-Amino-9-tert-butyl-9H-purine	IC50	10200.0 [1]
	6-Amino-9-tert-butyl-9H-purine	Ki	6900.0 [1]
	Thiazolo[5,4-d]pyrimidin-7-amine	IC50	116900.0 [1]
	Thiazolo[5,4-d]pyrimidin-7-amine	Ki	80600.0 [1]
	6-Amino-9-(adamantan-1-yl)-9H-purine	IC50	6000.0 [1]
	6-Amino-9-(adamantan-1-yl)-9H-purine	Ki	4100.0 [1]
	6-Amino-9-(1-methylcyclohexyl)-9H-purine	IC50	7200.0 [1]
	6-Amino-9-(1-methylcyclohexyl)-9H-purine	Ki	5000.0 [1]
	6-Amino-9-(4-tert-butylphenyl)-9H-purine	IC50	46100.0 [1]
	6-Amino-9-(4-tert-butylphenyl)-9H-purine	Ki	31700.0 [1]
	6-Amino-8-pentyl-9-phenyl-9H-purine	IC50	51900.0 [1]
	6-Amino-8-pentyl-9-phenyl-9H-purine	Ki	35800.0 [1]
	8-Methyl-9-phenyl-9H-purin-6-ylamine	IC50	16400.0 [1]
	8-Methyl-9-phenyl-9H-purin-6-ylamine	Ki	11000.0 [1]
	6-Amino-9-(2-fluorophenyl)-9H-purine	IC50	11900.0 [1]
	6-Amino-9-(2-fluorophenyl)-9H-purine	Ki	8300.0 [1]
	6-Amino-9-(3-pyridinyl)-9H-purine	IC50	46200.0 [1]
	6-Amino-9-(3-pyridinyl)-9H-purine	Ki	31800.0 [1]
	8,9-Tetramethyleneadenine	IC50	52400.0 [1]
	8,9-Tetramethyleneadenine	Ki	35800.0 [1]
	9H-Purin-6-amine, 8-(2-pyridinyl)-	IC50	75600.0 [1]
	9H-Purin-6-amine, 8-(2-pyridinyl)-	Ki	52300.0 [1]
	9H-Purin-6-amine, 8-pentyl-	IC50	68900.0 [1]
	9H-Purin-6-amine, 8-pentyl-	Ki	47500.0 [1]
	6-Amino-9-(1,1-diethylpropyl)-9H-purine	IC50	134100.0 [1]
	6-Amino-9-(1,1-diethylpropyl)-9H-purine	Ki	93700.0 [1]
	6-Amino-9-(2,2-dimethylpropyl)-9H-purine	IC50	12800.0 [1]
	6-Amino-9-(2,2-dimethylpropyl)-9H-purine	Ki	9000.0 [1]
	9-(3-Methoxyphenyl)adenine	IC50	22900.0 [1]
	9-(3-Methoxyphenyl)adenine	Ki	15800.0 [1]
	6-Amino-9-(3-fluorophenyl)-9H-purine	IC50	25600.0 [1]
	6-Amino-9-(3-fluorophenyl)-9H-purine	Ki	17900.0 [1]
	6-Amino-8,9-diphenyl-9H-purine	IC50	16400.0 [1]
	6-Amino-8,9-diphenyl-9H-purine	Ki	11000.0 [1]
	8-N-Benzyl-7H-purine-6,8-diamine;hydrochloride	IC50	133000.0 [1]
	8-N-Benzyl-7H-purine-6,8-diamine;hydrochloride	Ki	91700.0 [1]
	8-Bromo-7H-purin-6-amine;hydrochloride	IC50	215300.0 [1]
	8-Bromo-7H-purin-6-amine;hydrochloride	Ki	148400.0 [1]
	Benzo[g]quinazolin-4-amine	IC50	33000.0 [1]
	Benzo[g]quinazolin-4-amine	Ki	22700.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Phosphatidylinositol 4-kinase, PI4K Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/phosphatidylinositol-4-kinase-pi4k-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 21). Quest Database™ Phosphatidylinositol 4-kinase, PI4K Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phosphatidylinositol-4-kinase-pi4k-inhibitors-ic50-ki.
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