Phosphatidylcholine:ceramide cholinephosphotransferase 2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-N,1-dimethyl-2-oxo-4-pyrrolidin-1-ylquinoline-3-carboxamide	IC50	410.0 [1], 470.0 [2], 950.0 [3], 2900.0 [4]
	Anilino[2-(benzyloxy)phenyl]acetonitrile	IC50	13500.0 [1], 20900.0 [2]
	Potassium	IC50	224000.0 [1]
	[2-(Benzyloxy)phenyl](2-methoxyanilino)acetonitrile	IC50	12400.0 [1]
	8-Tricyclo[5.2.1.02,6]decanyloxymethanedithioic acid	IC50	56000.0 [1]
	[2-(Benzyloxy)phenyl][(4-methoxyphenyl)amino]acetonitrile	IC50	48100.0 [1]
	[2-(Benzyloxy)phenyl](4-toluidino)acetonitrile	IC50	20800.0 [1]
	Sms2-IN-2	IC50	100.0 [1]
	Sms2-IN-1	IC50	6.5 [1]
	2-[2-[(3-Fluorophenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridine	IC50	2300.0 [1]
	2-[2-[(2-Ethylphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridine	IC50	5000.0 [1]
	2-[2-[(3-Methoxyphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridine	IC50	3000.0 [1]
	2-[2-[(3-Chlorophenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridine	IC50	4100.0 [1]
	2-[2-[(3-Methylphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridine	IC50	17500.0 [1]
	2-(2-Phenylmethoxyphenyl)-[1,3]oxazolo[5,4-b]pyridine	IC50	16300.0 [1]
	2-[2-[(2-Methylphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridine	IC50	1700.0 [1]
	2-[2-[(2,6-Dimethylphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridine	IC50	4400.0 [1]
	2-[2-[(2-Methoxyphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridine	IC50	19100.0 [1]
	2-[2-[(3-Fluoro-2-methylphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridine	IC50	2300.0 [1]
	4-[(4-Chlorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	10000.0 [1]
	4-[(2-Phenylpyridin-4-yl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	10000.0 [1]
	4-[[3-(Pyridin-3-ylamino)-1,2-benzoxazol-4-yl]oxymethyl]benzonitrile	IC50	10000.0 [1]
	8-Phenylmethoxy-N-pyridin-3-ylisoquinolin-1-amine	IC50	10000.0 [1]
	2-[[3-(Pyridin-3-ylamino)-1,2-benzoxazol-4-yl]oxymethyl]benzonitrile	IC50	4400.0 [1]
	4-[(2,6-Dimethylphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	150.0 [1]
	4-[(2,6-Dichlorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	90.0 [1]
	4-Phenylmethoxy-N-pyridin-3-yl-1,2-benzothiazol-3-amine	IC50	1200.0 [1]
	3-[[3-(Pyridin-3-ylamino)-1,2-benzoxazol-4-yl]oxymethyl]benzonitrile	IC50	960.0 [1]
	4-[(2,6-Difluorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	740.0 [1]
	4-Phenylmethoxy-N-pyridin-3-yl-1H-indazol-3-amine	IC50	9100.0 [1]
	1-Methyl-4-phenylmethoxy-N-pyridin-3-ylindazol-3-amine	IC50	10000.0 [1]
	4-Phenylmethoxy-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	340.0 [1]
	4-[(2-Ethylphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	240.0 [1]
	4-[(2-Fluorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	670.0 [1]
	4-[(2-Chlorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	270.0 [1]
	4-[(3-Chlorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	100.0 [1]
	4-[(4-Fluorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	1700.0 [1]
	4-[(2-Methylphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	470.0 [1]
	4-[(4-Methylphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	10000.0 [1]
	4-[(3-Methylphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	190.0 [1]
	4-[(3-Fluorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	160.0 [1]
	4-[(2-Methoxyphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	240.0 [1]
	N-Pyridin-3-yl-4-[[3-(trifluoromethoxy)phenyl]methoxy]-1,2-benzoxazol-3-amine	IC50	1300.0 [1]
	N-Pyridin-3-yl-4-[[4-(trifluoromethoxy)phenyl]methoxy]-1,2-benzoxazol-3-amine	IC50	10000.0 [1]
	4-[(3-Methoxyphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	520.0 [1]
	N-Pyridin-3-yl-4-[[2-(trifluoromethoxy)phenyl]methoxy]-1,2-benzoxazol-3-amine	IC50	110.0 [1]
	4-[(4-Methoxyphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	10000.0 [1]
	N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-N,1-dimethyl-2-oxo-4-[(2-phenylpyridin-4-yl)methoxy]quinoline-3-carboxamide	IC50	16.0 [1]
	4-(1,3-Benzoxazol-2-ylmethoxy)-N-pyridin-3-yl-1,2-benzoxazol-3-amine	IC50	10000.0 [1]
	2-Phenylmethoxy-N-pyridin-3-ylbenzamide	IC50	1500.0 [1]
	2-(2-Hydroxyphenyl)-3-phenyl-2,4-dihydro-1,3-benzoxazine-4-carbonitrile	IC50	75000.0 [1]
	[2-(Benzyloxy)phenyl][(2-methylphenyl)amino]acetonitrile	IC50	67200.0 [1]
	2-(4-Hydroxyanilino)-2-(2-phenylmethoxyphenyl)acetonitrile	IC50	24400.0 [1]
	2-(2,6-Dimethylanilino)-2-(2-phenylmethoxyphenyl)acetonitrile	IC50	31500.0 [1]
	4-[[Cyano-(2-phenylmethoxyphenyl)methyl]amino]benzamide	IC50	80500.0 [1]
	2-(2-Nitroanilino)-2-(2-phenylmethoxyphenyl)acetonitrile	IC50	27400.0 [1]
	2-Anilino-2-(3-phenylmethoxyphenyl)acetonitrile	IC50	50700.0 [1]
	2-(2-Chloroanilino)-2-(2-phenylmethoxyphenyl)acetonitrile	IC50	15800.0 [1]
	2-(4-Chloroanilino)-2-(2-phenylmethoxyphenyl)acetonitrile	IC50	22500.0 [1]
	2-(2-Hydroxyanilino)-2-(2-phenylmethoxyphenyl)acetonitrile	IC50	19000.0 [1]
	2-(2-Phenylmethoxyphenyl)-2-(pyridin-3-ylamino)acetonitrile	IC50	35000.0 [1]
	2-Anilino-2-(2-phenylmethoxyphenyl)acetamide	IC50	135300.0 [1]
	2-[[Cyano-(2-phenylmethoxyphenyl)methyl]amino]benzonitrile	IC50	20300.0 [1]
	2-(Furan-2-ylmethylamino)-2-(2-phenylmethoxyphenyl)acetonitrile	IC50	71000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 64 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Phosphatidylcholine:ceramide cholinephosphotransferase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 19 Feb. 2025, https://www.aatbio.com/data-sets/phosphatidylcholine-ceramide-cholinephosphotransferase-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 19). Quest Database™ Phosphatidylcholine:ceramide cholinephosphotransferase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phosphatidylcholine-ceramide-cholinephosphotransferase-2-inhibitors-ic50-ki.
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