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Phosphatidylcholine:ceramide cholinephosphotransferase 2 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-N,1-dimethyl-2-oxo-4-pyrrolidin-1-ylquinoline-3-carboxamideIC50410.0 [1], 470.0 [2], 950.0 [3], 2900.0 [4]
Anilino[2-(benzyloxy)phenyl]acetonitrileIC5013500.0 [1], 20900.0 [2]
PotassiumIC50224000.0 [1]
[2-(Benzyloxy)phenyl](2-methoxyanilino)acetonitrileIC5012400.0 [1]
8-Tricyclo[5.2.1.02,6]decanyloxymethanedithioic acidIC5056000.0 [1]
[2-(Benzyloxy)phenyl][(4-methoxyphenyl)amino]acetonitrileIC5048100.0 [1]
[2-(Benzyloxy)phenyl](4-toluidino)acetonitrileIC5020800.0 [1]
Sms2-IN-2IC50100.0 [1]
Sms2-IN-1IC506.5 [1]
2-[2-[(3-Fluorophenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridineIC502300.0 [1]
2-[2-[(2-Ethylphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridineIC505000.0 [1]
2-[2-[(3-Methoxyphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridineIC503000.0 [1]
2-[2-[(3-Chlorophenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridineIC504100.0 [1]
2-[2-[(3-Methylphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridineIC5017500.0 [1]
2-(2-Phenylmethoxyphenyl)-[1,3]oxazolo[5,4-b]pyridineIC5016300.0 [1]
2-[2-[(2-Methylphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridineIC501700.0 [1]
2-[2-[(2,6-Dimethylphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridineIC504400.0 [1]
2-[2-[(2-Methoxyphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridineIC5019100.0 [1]
2-[2-[(3-Fluoro-2-methylphenyl)methoxy]phenyl]-[1,3]oxazolo[5,4-b]pyridineIC502300.0 [1]
4-[(4-Chlorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC5010000.0 [1]
4-[(2-Phenylpyridin-4-yl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC5010000.0 [1]
4-[[3-(Pyridin-3-ylamino)-1,2-benzoxazol-4-yl]oxymethyl]benzonitrileIC5010000.0 [1]
8-Phenylmethoxy-N-pyridin-3-ylisoquinolin-1-amineIC5010000.0 [1]
2-[[3-(Pyridin-3-ylamino)-1,2-benzoxazol-4-yl]oxymethyl]benzonitrileIC504400.0 [1]
4-[(2,6-Dimethylphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50150.0 [1]
4-[(2,6-Dichlorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC5090.0 [1]
4-Phenylmethoxy-N-pyridin-3-yl-1,2-benzothiazol-3-amineIC501200.0 [1]
3-[[3-(Pyridin-3-ylamino)-1,2-benzoxazol-4-yl]oxymethyl]benzonitrileIC50960.0 [1]
4-[(2,6-Difluorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50740.0 [1]
4-Phenylmethoxy-N-pyridin-3-yl-1H-indazol-3-amineIC509100.0 [1]
1-Methyl-4-phenylmethoxy-N-pyridin-3-ylindazol-3-amineIC5010000.0 [1]
4-Phenylmethoxy-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50340.0 [1]
4-[(2-Ethylphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50240.0 [1]
4-[(2-Fluorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50670.0 [1]
4-[(2-Chlorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50270.0 [1]
4-[(3-Chlorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50100.0 [1]
4-[(4-Fluorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC501700.0 [1]
4-[(2-Methylphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50470.0 [1]
4-[(4-Methylphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC5010000.0 [1]
4-[(3-Methylphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50190.0 [1]
4-[(3-Fluorophenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50160.0 [1]
4-[(2-Methoxyphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50240.0 [1]
N-Pyridin-3-yl-4-[[3-(trifluoromethoxy)phenyl]methoxy]-1,2-benzoxazol-3-amineIC501300.0 [1]
N-Pyridin-3-yl-4-[[4-(trifluoromethoxy)phenyl]methoxy]-1,2-benzoxazol-3-amineIC5010000.0 [1]
4-[(3-Methoxyphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC50520.0 [1]
N-Pyridin-3-yl-4-[[2-(trifluoromethoxy)phenyl]methoxy]-1,2-benzoxazol-3-amineIC50110.0 [1]
4-[(4-Methoxyphenyl)methoxy]-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC5010000.0 [1]
N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-N,1-dimethyl-2-oxo-4-[(2-phenylpyridin-4-yl)methoxy]quinoline-3-carboxamideIC5016.0 [1]
4-(1,3-Benzoxazol-2-ylmethoxy)-N-pyridin-3-yl-1,2-benzoxazol-3-amineIC5010000.0 [1]
2-Phenylmethoxy-N-pyridin-3-ylbenzamideIC501500.0 [1]
2-(2-Hydroxyphenyl)-3-phenyl-2,4-dihydro-1,3-benzoxazine-4-carbonitrileIC5075000.0 [1]
[2-(Benzyloxy)phenyl][(2-methylphenyl)amino]acetonitrileIC5067200.0 [1]
2-(4-Hydroxyanilino)-2-(2-phenylmethoxyphenyl)acetonitrileIC5024400.0 [1]
2-(2,6-Dimethylanilino)-2-(2-phenylmethoxyphenyl)acetonitrileIC5031500.0 [1]
4-[[Cyano-(2-phenylmethoxyphenyl)methyl]amino]benzamideIC5080500.0 [1]
2-(2-Nitroanilino)-2-(2-phenylmethoxyphenyl)acetonitrileIC5027400.0 [1]
2-Anilino-2-(3-phenylmethoxyphenyl)acetonitrileIC5050700.0 [1]
2-(2-Chloroanilino)-2-(2-phenylmethoxyphenyl)acetonitrileIC5015800.0 [1]
2-(4-Chloroanilino)-2-(2-phenylmethoxyphenyl)acetonitrileIC5022500.0 [1]
2-(2-Hydroxyanilino)-2-(2-phenylmethoxyphenyl)acetonitrileIC5019000.0 [1]
2-(2-Phenylmethoxyphenyl)-2-(pyridin-3-ylamino)acetonitrileIC5035000.0 [1]
2-Anilino-2-(2-phenylmethoxyphenyl)acetamideIC50135300.0 [1]
2-[[Cyano-(2-phenylmethoxyphenyl)methyl]amino]benzonitrileIC5020300.0 [1]
2-(Furan-2-ylmethylamino)-2-(2-phenylmethoxyphenyl)acetonitrileIC5071000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Phosphatidylcholine:ceramide cholinephosphotransferase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Nov2024https://www.aatbio.com/data-sets/phosphatidylcholine-ceramide-cholinephosphotransferase-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 21). Quest Database™ Phosphatidylcholine:ceramide cholinephosphotransferase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phosphatidylcholine-ceramide-cholinephosphotransferase-2-inhibitors-ic50-ki.
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