Peroxisome proliferator-activated receptor gamma Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Rosiglitazone	IC50	210.0 [1]
	Pioglitazone	IC50	8000.0 [1], 22000.0 [2]
	Pioglitazone	Ki	630.0 [1], 1230.27 [2]
	Troglitazone	IC50	300.0 [1], 340.0 [2], 370.0 [3], 1285.0 [4], 2600.0 [5]
	Troglitazone	Ki	302.0 [1], 380.0 [2], 3800.0 [3]
	Fenofibric acid	IC50	10000.0 [1], 25000.0 [2], 50000.0 [3]
	Farglitazar	IC50	217.0 [1]
	Farglitazar	Ki	1.1 [1], 1.15 [2], 111943788.35 [3]
	5-[3-[3-(4-Phenoxy-2-propylphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	IC50	57.0 [1]
	5-[3-[3-(4-Phenoxy-2-propylphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	Ki	60.0 [1]
	F3MethylAA	IC50	140.0 [1], 195.0 [2]
	Endurobol	IC50	6309.57 [1]
	Muraglitazar	IC50	120.0 [1], 190.0 [2], 250.0 [3]
	(S)-2-(2-Benzoylphenylamino)-3-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)phenyl)propanoic acid	Ki	0.05 [1], 1.41 [2], 113240036.32 [3]
	N-(2-(Methoxycarbonyl)phenyl]-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl)-L-tyrosine	IC50	10000.0 [1]
	N-(2-(Methoxycarbonyl)phenyl]-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl)-L-tyrosine	Ki	3.7 [1], 3.71 [2]
	Benzeneacetic acid, 3-chloro-4-((3-((3-phenyl-7-propyl-6-benzofuranyl)oxy)propyl)thio)-	IC50	93.97 [1], 94.0 [2]
	(2S)-2-(4-[2-(3-[2,4-Difluorophenyl]-1-heptylureido)ethyl]phenoxy)-2-methylbutyric acid	IC50	316.0 [1], 600.0 [2], 670.0 [3]
	(2S)-2-[3-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]propanoic acid	IC50	1.0 [1], 2.0 [2]
	CID 9889841	IC50	109.9 [1], 110.0 [2]
	2-Methyl-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2-phenoxy-propionic acid	IC50	18.0 [1]
	2-Methyl-2-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenoxy}-3-phenyl-propionic acid	IC50	491.0 [1]
	(R)-3-(4-(3-(2-Benzoyl-4-ethylphenoxy)butoxy)-2-methylphenyl)propanoic acid	IC50	5.0 [1]
	{3-Chloro-4-[3-(3-hydroxy-4-propionyl-2-propyl-phenoxy)-propylsulfanyl]-phenyl}-acetic acid	IC50	299.92 [1], 300.0 [2]
	2-[4-[3-[2-Chloro-4-(4-fluorophenoxy)phenoxy]propoxy]phenoxy]-2-methylpropanoic acid	IC50	981.0 [1]
	{4-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-propylsulfanyl]-3-chloro-phenyl}-acetic acid	IC50	579.43 [1], 580.0 [2]
	{3-Chloro-4-[3-(3-ethyl-7-propyl-benzofuran-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid	IC50	560.0 [1]
	2,4-Thiazolidiinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-(9CL)	IC50	30.0 [1], 60.0 [2], 210.0 [3]
	2-{5-[3-(7-Propyl-3-trifluoromethylbenzo[D]isoxazol-6-yloxy)propoxy]indol-1-YL}ethanoic acid	IC50	152.0 [1], 152.05 [2]
	5-[[4-[2-[1,3-Benzoxazol-2-yl(methyl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione	Ki	22.0 [1], 26.92 [2]
	2-Phenyl-3-(4-methoxyphenethyl)-1H-indole-5-acetic acid	IC50	50.0 [1]
	2-Phenyl-3-(4-methoxyphenethyl)-1H-indole-5-acetic acid	Ki	47.86 [1], 50.0 [2]
	4'-((5-(Benzylcarbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid	IC50	1.0 [1], 41.0 [2]
	(S)-3-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2-pyrrol-1-yl-propionic acid	IC50	29.0 [1]
	(S)-3-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2-pyrrol-1-yl-propionic acid	Ki	6.9 [1]
	Rosiglitazone maleate	Ki	14.0 [1], 136.0 [2]
	Ciglitazone	IC50	5000.0 [1]
	Ciglitazone	Ki	3090.3 [1]
	Tesaglitazar	IC50	350.0 [1]
	Tesaglitazar	Ki	18.0 [1]
	Ragaglitazar	IC50	92.0 [1]
	Ragaglitazar	Ki	90.0 [1]
	5-((2,4-Dioxo-5-thiazolidinyl)methyl)-2-methoxy-N-((4-(trifluoromethyl)phenyl)methyl)benzamide	IC50	463.0 [1]
	5-((2,4-Dioxo-5-thiazolidinyl)methyl)-2-methoxy-N-((4-(trifluoromethyl)phenyl)methyl)benzamide	Ki	330.0 [1]
	Benzenesulfonamide, 2,4-dichloro-N-(3,5-dichloro-4-(3-quinolinyloxy)phenyl)-	IC50	17.0 [1]
	Benzenesulfonamide, 2,4-dichloro-N-(3,5-dichloro-4-(3-quinolinyloxy)phenyl)-	Ki	10.0 [1]
	LY-518674	IC50	6500.0 [1], 6501.3 [2]
	Naveglitazar	IC50	33.96 [1], 34.0 [2]
	2-[4-[[2,3-Dimethyl-5-[[(1S)-1-(4-nitrophenyl)ethyl]carbamoyl]indol-1-yl]methyl]phenyl]benzoic acid	IC50	80.0 [1]
	CID 9890319	IC50	548.0 [1]
	CID 9890319	Ki	550.0 [1]
	5-[[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione	IC50	14.0 [1]
	5-[[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione	Ki	4.27 [1]
	(2S)-2-Methyl-3-[4-[2-(5-methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-phenoxypropanoic acid	IC50	10.0 [1]
	Trp-glu	IC50	8670.0 [1]
	2-Methyl-3-[4-[2-(5-methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-phenoxypropanoic acid	IC50	24.0 [1]
	2-Methyl-3-[4-[2-(5-methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-phenoxypropanoic acid	Ki	3.0 [1]
	2-{5-[3-(6-Benzoyl-1-propylnaphthalen-2-yloxy)propoxy]indol-1-YL}ethanoic acid	IC50	50.0 [1]
	4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide	IC50	25118.86 [1]
	(2S)-2-Methyl-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-phenoxypropanoic acid	IC50	14.0 [1]
	(2R)-7-(3-(2-Chloro-4-(4-fluorophenoxy)phenoxy)propoxy)-2-ethylchromane-2-carboxylic acid	IC50	260.0 [1]
	2-Methyl-2-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenoxy}propionic Acid	IC50	2570.0 [1], 3017.0 [2]
	(2R)-2-Methyl-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-phenoxypropanoic acid	IC50	388.0 [1], 388.15 [2]
	3-[4-[3-[(1R)-1-[(5-Chloro-1,3-dimethylindole-2-carbonyl)amino]ethyl]-5-fluorophenoxy]-2-ethylphenyl]propanoic acid	IC50	38.99 [1], 39.0 [2]
	3-Fluoro-N-[1-(4-fluorophenyl)-3-(2-thienyl)-1H-pyrazol-5-YL]benzenesulfonamide	IC50	512.0 [1]
	5-[3-[3-[2-Propyl-4-(3,4-dichlorophenoxy)phenoxy]propoxy]phenyl]thiazolidine-2,4-dione	IC50	64.0 [1]
	5-[3-[3-(4-Benzoyl-2-propylphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	IC50	19.0 [1]
	2-[4-[[2,3-Dimethyl-5-(1-phenylpropylcarbamoyl)indol-1-yl]methyl]phenyl]benzoic acid	IC50	0.37 [1], 8.0 [2]
	2-[4-[[5-[[(1S)-1-(4-Bromophenyl)ethyl]carbamoyl]-2,3-dimethylindol-1-yl]methyl]phenyl]benzoic acid	IC50	28.0 [1]
	(2S)-2-Methoxy-3-{4-[5-(4-phenoxy-phenoxy)-pent-1-ynyl]-phenyl}-propionic acid	IC50	7.0 [1]
	2-[4-[3-[1-[(3,4-Dimethylphenyl)methyl]-4-methyl-5-oxo-1,2,4-triazol-3-yl]propyl]phenoxy]-2-methylpropanoic acid	IC50	1698.24 [1], 1700.0 [2]
	(2R)-7-(3-(2-Chloro-4-cyclopentylphenoxy)propoxy)-2-methylchromane-2-carboxylic Acid	IC50	3800.0 [1], 3801.89 [2]
	(S)-2-Ethoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-propionic acid	IC50	43.95 [1], 44.0 [2]
	(S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-ynyl]-phenyl}-propionic acid	IC50	13.0 [1]
	(R)-7-[3-(2-Chloro-4-isobutyl-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid	IC50	2999.16 [1], 3000.0 [2]
	2-[4-[3-[1-[(4-Tert-butylphenyl)methyl]-4-methyl-5-oxo-1,2,4-triazol-3-yl]propyl]phenoxy]-2-methylpropanoic acid	IC50	520.0 [1]
	2-(4-(4-(4-(Trifluoromethyl)benzyloxy)benzylthio)-5-methoxy-2-methylphenoxy)acetic acid	IC50	23600.0 [1]
	2-[4-[3-[1-[(3-Methoxyphenyl)methyl]-5-oxo-4-propyl-1,2,4-triazol-3-yl]propyl]phenoxy]-2-methylpropanoic acid	IC50	6194.41 [1], 6200.0 [2]
	(S)-3-[4-[2-[Methyl(benzoxazol-2-yl)amino]ethoxy]phenyl]-2-[(2-benzoylphenyl)amino]propionic acid	Ki	1.48 [1], 112201845.43 [2]
	(R)-7-[3-(2-Chloro-4-trifluoromethyl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid	IC50	4295.36 [1], 4300.0 [2]
	(S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-phenyl}-2-methoxy-propionic acid	IC50	20.99 [1], 21.0 [2]
	(S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-phenyl}-2-methoxy-propionic acid	IC50	5.0 [1]
	(S)-2-Methoxy-3-{3-methoxy-4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-propionic acid	IC50	13.0 [1]
	(2S)-2-[4-Chloro-3-[1-(6-chloro-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]oxyphenoxy]propanoic acid	IC50	5.0 [1], 6.0 [2]
	3-[4-[2-[1,3-Benzoxazol-2-yl(methyl)amino]ethoxy]phenyl]-2-(2-benzoylphenyl)sulfanylpropanoic acid	Ki	33.11 [1], 132129563.42 [2]
	(2S)-2-[(2-Benzoylcyclohexen-1-yl)amino]-3-(4-phenylmethoxyphenyl)propanoic acid	Ki	794.33 [1], 147570653.33 [2]
	3-[4-[2-[1,3-Benzoxazol-2-yl(methyl)amino]ethoxy]phenyl]-2-(2-benzoylphenoxy)propanoic acid	Ki	32.36 [1], 133659551.65 [2]
	3-[4-[2-[1,3-Benzoxazol-2-yl(methyl)amino]ethoxy]phenyl]-2-[(9,10-dioxoanthracen-1-yl)amino]propanoic acid	Ki	5.13 [1], 120781383.51 [2]
	(2S)-2-(2-Benzoylanilino)-3-[4-[(1-methylcyclohexyl)methoxy]phenyl]propanoic acid	Ki	51.29 [1], 137404197.5 [2]
	2-[2-(Benzenesulfonyl)anilino]-3-[4-[2-[1,3-benzoxazol-2-yl(methyl)amino]ethoxy]phenyl]propanoic acid	Ki	123.03 [1], 147570653.33 [2]
	(2S)-2-(2-Benzoylanilino)-3-[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]propanoic acid	Ki	6.46 [1], 122179966.02 [2]
	3-[4-[2-[1,3-Benzoxazol-2-yl(methyl)amino]ethoxy]phenyl]-2-[2-(2-phenylacetyl)anilino]propanoic acid	Ki	3.31 [1], 118032063.57 [2]
	(2S)-2-(2-Benzoylanilino)-3-[4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl)methoxy]phenyl]propanoic acid	Ki	5.25 [1], 120781383.51 [2]
	3-[4-[2-[1,3-Benzoxazol-2-yl(methyl)amino]ethoxy]phenyl]-2-[(9-oxofluoren-1-yl)amino]propanoic acid	Ki	85.11 [1], 141579378.0 [2]
	3-[2-Ethyl-4-[(3R)-3-(4-ethyl-2-pyridin-2-ylphenoxy)butoxy]phenyl]propanoic acid	IC50	34.99 [1], 35.0 [2]
	3-[4-[(3R)-3-(4-Ethyl-2-pyridin-2-ylphenoxy)butoxy]-2-methylphenyl]propanoic acid	IC50	46.0 [1], 46.03 [2]
	(2S)-3-[4-[2-(2-Cyclohexyl-5-methyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-methyl-2-phenoxypropanoic acid	IC50	15.0 [1]
	3-[4-[(3R)-3-[4-Ethyl-2-(1,3-oxazol-2-yl)phenoxy]butoxy]-2-methylphenyl]propanoic acid	IC50	483.0 [1], 483.06 [2]
	2-[5-[3-(6-Benzoylnaphthalen-2-yl)oxypropoxy]indol-1-yl]acetic acid	IC50	629.0 [1], 629.51 [2]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 99 ⟨⟩

---

---

References

This online tool may be cited as follows

MLA	"Quest Database™ Peroxisome proliferator-activated receptor gamma Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Dec. 2024, https://www.aatbio.com/data-sets/peroxisome-proliferator-activated-receptor-gamma-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 22). Quest Database™ Peroxisome proliferator-activated receptor gamma Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/peroxisome-proliferator-activated-receptor-gamma-inhibitors-ic50-ki.
BibTeX	EndNote	RefMan