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Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
JugloneIC505900.0 [1], 10030.0 [2], 10120.0 [3], 10810.0 [4]
Cyclic crypeveicIC50500.0 [1]
Cyclic crypeveicKi200.0 [1], 520.0 [2]
[(2R)-2-(1-Benzothiophene-2-carbonylamino)-3-(3-fluorophenyl)propyl] dihydrogen phosphateIC506.0 [1], 50.0 [2]
[(2R)-2-(1-Benzothiophene-2-carbonylamino)-3-(3-fluorophenyl)propyl] dihydrogen phosphateKi6.0 [1]
Acetyl-11-keto-beta-boswellic acidIC5050360.0 [1], 52990.0 [2]
ProcodazoleIC5010000.0 [1], 740000.0 [2]
1,7-Diphenylheptan-4-yl (2S)-1-[[(2R)-1-phenyl-3-phosphonooxypropan-2-yl]carbamoyl]piperidine-2-carboxylateIC50800.0 [1]
1,7-Diphenylheptan-4-yl (2S)-1-[[(2R)-1-phenyl-3-phosphonooxypropan-2-yl]carbamoyl]piperidine-2-carboxylateKi800.0 [1]
[(2R)-2-(1-Benzothiophene-2-carbonylamino)-3-phenylpropyl] dihydrogen phosphateIC50180.0 [1]
[(2R)-2-(1-Benzothiophene-2-carbonylamino)-3-phenylpropyl] dihydrogen phosphateKi179.0 [1]
(2R)-3-(6-Fluoro-1H-indol-2-yl)-2-(naphthalene-2-carbonylamino)propanoic acidIC502960.0 [1]
(2R)-3-(6-Fluoro-1H-indol-2-yl)-2-(naphthalene-2-carbonylamino)propanoic acidKi138.0 [1]
3-Fluoro-N-(naphthalen-2-ylcarbonyl)-D-phenylalanineIC5012000.0 [1]
3-Fluoro-N-(naphthalen-2-ylcarbonyl)-D-phenylalanineKi12000.0 [1]
Piperidine-1-dithiocarboxylic acid, anhydrosulphideIC504000.0 [1]
Piperidine-1-dithiocarboxylic acid, anhydrosulphideKi50.0 [1]
(2R,4E)-2-[(Naphthalen-2-ylcarbonyl)amino]-5-phenylpent-4-enoic acidIC5050000.0 [1]
(2R,4E)-2-[(Naphthalen-2-ylcarbonyl)amino]-5-phenylpent-4-enoic acidKi1800.0 [1]
(3R)-4-(3-Fluorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acidIC5050000.0 [1]
(3R)-4-(3-Fluorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acidKi5700.0 [1]
(2R)-3-(3-Methylphenyl)-2-(naphthalene-2-carbonylamino)propanoic acidIC5050000.0 [1]
(2R)-3-(3-Methylphenyl)-2-(naphthalene-2-carbonylamino)propanoic acidKi2800.0 [1]
(3R)-4-(3-Methylphenyl)-3-(naphthalene-2-carbonylamino)butanoic acidIC5050000.0 [1]
(3R)-4-(3-Methylphenyl)-3-(naphthalene-2-carbonylamino)butanoic acidKi9700.0 [1]
(2R)-3-(3-Cyanophenyl)-2-(naphthalene-2-carbonylamino)propanoic acidIC5050000.0 [1]
(2R)-3-(3-Cyanophenyl)-2-(naphthalene-2-carbonylamino)propanoic acidKi3200.0 [1]
(3R)-4-(3-Cyanophenyl)-3-(naphthalene-2-carbonylamino)butanoic acidIC5050000.0 [1]
(3R)-4-(3-Cyanophenyl)-3-(naphthalene-2-carbonylamino)butanoic acidKi2300.0 [1]
(2R)-2-(Naphthalene-2-carbonylamino)-3-[3-(trifluoromethyl)phenyl]propanoic acidIC5050000.0 [1]
(2R)-2-(Naphthalene-2-carbonylamino)-3-[3-(trifluoromethyl)phenyl]propanoic acidKi1800.0 [1]
(3R)-3-(Naphthalene-2-carbonylamino)-4-[3-(trifluoromethyl)phenyl]butanoic acidIC5050000.0 [1]
(3R)-3-(Naphthalene-2-carbonylamino)-4-[3-(trifluoromethyl)phenyl]butanoic acidKi13000.0 [1]
(2R)-3-(3-Chlorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acidIC5050000.0 [1]
(2R)-3-(3-Chlorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acidKi3400.0 [1]
(3R)-4-(3-Chlorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acidIC5050000.0 [1]
(3R)-4-(3-Chlorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acidKi2000.0 [1]
(2R)-3-(3,4-Difluorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acidIC5050000.0 [1]
(2R)-3-(3,4-Difluorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acidKi23000.0 [1]
(3R)-4-(3,4-Difluorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acidIC5050000.0 [1]
(3R)-4-(3,4-Difluorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acidKi82000.0 [1]
(2R)-3-(3,4-Dichlorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acidIC5050000.0 [1]
(2R)-3-(3,4-Dichlorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acidKi2200.0 [1]
(2R)-2-(Naphthalene-2-carbonylamino)-3-(3,4,5-trifluorophenyl)propanoic acidIC5050000.0 [1]
(2R)-2-(Naphthalene-2-carbonylamino)-3-(3,4,5-trifluorophenyl)propanoic acidKi9000.0 [1]
(2R)-3-(4-Cyanophenyl)-2-(naphthalene-2-carbonylamino)propanoic acidIC5050000.0 [1]
(2R)-3-(4-Cyanophenyl)-2-(naphthalene-2-carbonylamino)propanoic acidKi3000.0 [1]
(R)-N-(2-(4-Fluorophenyl)-1-(1H-tetrazol-5-yl)ethyl)-2-naphthamideIC5050000.0 [1]
(R)-N-(2-(4-Fluorophenyl)-1-(1H-tetrazol-5-yl)ethyl)-2-naphthamideKi4000.0 [1]
N-[(1R)-1-(2H-Tetrazol-5-yl)-2-[4-(trifluoromethyl)phenyl]ethyl]naphthalene-2-carboxamideIC5050000.0 [1]
N-[(1R)-1-(2H-Tetrazol-5-yl)-2-[4-(trifluoromethyl)phenyl]ethyl]naphthalene-2-carboxamideKi8500.0 [1]
(2R)-2-(Naphthalene-2-carbonylamino)-5-phenylpent-4-ynoic acidIC5050000.0 [1]
(2R)-2-(Naphthalene-2-carbonylamino)-5-phenylpent-4-ynoic acidKi12800.0 [1]
(2R)-5-(3-Fluorophenyl)-2-(naphthalene-2-carbonylamino)pent-4-ynoic acidIC5050000.0 [1]
(2R)-5-(3-Fluorophenyl)-2-(naphthalene-2-carbonylamino)pent-4-ynoic acidKi1870.0 [1]
(2R)-5-(2-Hydroxyphenyl)-2-(naphthalene-2-carbonylamino)pent-4-ynoic acidIC5050000.0 [1]
(2R)-5-(2-Hydroxyphenyl)-2-(naphthalene-2-carbonylamino)pent-4-ynoic acidKi4430.0 [1]
(2R)-2-(Naphthalene-2-carbonylamino)-5-thiophen-2-ylpent-4-ynoic acidIC5050000.0 [1]
(2R)-2-(Naphthalene-2-carbonylamino)-5-thiophen-2-ylpent-4-ynoic acidKi7000.0 [1]
(E,2R)-5-(3-Fluorophenyl)-2-(naphthalene-2-carbonylamino)pent-4-enoic acidIC5050000.0 [1]
(E,2R)-5-(3-Fluorophenyl)-2-(naphthalene-2-carbonylamino)pent-4-enoic acidKi890.0 [1]
(R)-2-(Benzo[b]thiophene-2-carboxamido)-5-phenylpent-4-enoic acidIC5050000.0 [1]
(R)-2-(Benzo[b]thiophene-2-carboxamido)-5-phenylpent-4-enoic acidKi3700.0 [1]
(E,2R)-5-(Cyclohexen-1-yl)-2-(naphthalene-2-carbonylamino)pent-4-enoic acidIC5050000.0 [1]
(E,2R)-5-(Cyclohexen-1-yl)-2-(naphthalene-2-carbonylamino)pent-4-enoic acidKi2000.0 [1]
CycloheximideKi200000.0 [1]
TretinoinIC50820.0 [1]
(-)-Epigallocatechin gallateIC5020000.0 [1]
EnoxoloneIC5010000.0 [1]
5-Pyridin-2-yl-1H-pyrazole-3-carboxylic acidIC50720000.0 [1]
5-(2-Methoxyphenyl)-2-furoic acidIC501000000.0 [1]
5-Methyl-1H-indole-2-carboxylic acidIC5016000.0 [1]
PPIase-Parvulin InhibitorIC501500.0 [1]
6-Methyl-1H-indole-2-carboxylic acidIC50630000.0 [1]
2-Phenyl-1H-imidazole-4-carboxylic acidIC50180000.0 [1]
2-(3-Chloro-4-fluorophenyl)-3(2H)-isothiazoloneIC506100.0 [1]
2-Chloro-N-cyclopentyl-5-nitropyrimidin-4-amineIC50100000.0 [1]
Elemonic acidIC5013160.0 [1]
2-Phenyl-1H-imidazole-4,5-dicarboxylic acidIC501460.0 [1]
[(2R)-2-[[(2S)-2-[[(2S)-2-Acetamidopropanoyl]amino]propanoyl]amino]-3-[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphateIC501000.0 [1]
2-Chloro-4-cyclohexyloxy-5-nitropyrimidineIC50100000.0 [1]
2-Chloro-4-cyclopentyloxy-5-nitropyrimidineIC50100000.0 [1]
2-(2-Chloro-5-nitropyrimidin-4-yl)oxybenzonitrileIC509050.0 [1]
2-Chloro-4-naphthalen-1-yloxy-5-nitropyrimidineIC5022600.0 [1]
2-Chloro-4-naphthalen-2-yloxy-5-nitropyrimidineIC5016550.0 [1]
[(2R,3Z)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-[(2R)-2-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]cyclopentylidene]propyl] dihydrogen phosphateIC501500.0 [1]
2-Chloro-4-(3-methoxyphenoxy)-5-nitropyrimidineIC505040.0 [1]
2-Chloro-4-(2-fluorophenoxy)-5-nitropyrimidineIC502520.0 [1]
2-Chloro-4-(2-methoxyphenoxy)-5-nitropyrimidineIC504030.0 [1]
(2R)-2-[[2-(9H-Fluoren-9-yl)acetyl]amino]-3-(6-fluoro-1H-indol-2-yl)propanoic acidKi12.0 [1]
2-[2-(2,6-Dichlorophenyl)ethyl]-4-[(6-fluoro-1H-indol-2-yl)methyl]-5H-1,3-thiazole-4-carboxylic acidKi196.0 [1]
[(2R,3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-[5-[(3As,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-2-acetamidohexanoyl]amino]propanoyl]amino]propanoyl]amino]-3-thiophen-2-ylpropanoyl]amino]-4-[(2S)-2-[[(2S)-1-[[(2S)-1,5-diamino-1,5-dioxopentan-2-yl]amino]-1-oxo-3-(4-phenylphenyl)propan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-oxobutan-2-yl] dihydrogen phosphateIC5022000.0 [1]
(2R)-2-(1-Benzothiophene-2-carbonylamino)-3-(6-fluoro-1H-benzimidazol-2-yl)propanoic acidKi76.0 [1]
2-[(E)-2-(2,6-Dichlorophenyl)ethenyl]-4-[(6-fluoro-1H-indol-2-yl)methyl]-5H-1,3-thiazole-4-carboxylic acidKi580.0 [1]
[(2R,3R)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-[5-[(3As,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-2-acetamidohexanoyl]amino]propanoyl]amino]propanoyl]amino]-3-(1-benzothiophen-3-yl)propanoyl]amino]-4-[(2S)-2-[[(2S)-1-[[(2S)-1,5-diamino-1,5-dioxopentan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]carbamoyl]piperidin-1-yl]-4-oxobutan-2-yl] dihydrogen phosphateKi1.2 [1]
2-(9H-Fluoren-9-ylmethyl)-4-[(6-fluoro-1H-indol-2-yl)methyl]-5H-1,3-thiazole-4-carboxylic acidKi320.0 [1]
3-(6-Fluoro-1h-Benzimidazol-2-Yl)-N-(Naphthalen-2-Ylcarbonyl)-D-AlanineKi80.0 [1]
4-[(6-Fluoro-1H-indol-2-yl)methyl]-2-naphthalen-2-yl-5H-1,3-thiazole-4-carboxylic acidKi1360.0 [1]
(2R)-2-[3-(2,6-Dichlorophenyl)propanoylamino]-3-(6-fluoro-1H-indol-2-yl)propanoic acidKi75.0 [1]
[(2R)-3-(3-Methylphenyl)-2-(naphthalene-2-carbonylamino)propyl] dihydrogen phosphateKi32.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Nov2024https://www.aatbio.com/data-sets/peptidyl-prolyl-cis-trans-isomerase-nima-interacting-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 21). Quest Database™ Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/peptidyl-prolyl-cis-trans-isomerase-nima-interacting-1-inhibitors-ic50-ki.
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