Peptidyl-glycine alpha-amidating monooxygenase Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Decanoyloxyacetic acid	IC50	40.0 [1], 50.0 [2], 120.0 [3], 30000.0 [4]
	2-[(2S)-2-Acetamido-3-phenylpropanoyl]oxyacetic acid	IC50	5000.0 [1], 6000.0 [2], 11000.0 [3]
	Acetoxyacetic acid	IC50	1100000.0 [1]
	2-[(2S)-2-Amino-3-phenylpropanoyl]oxyacetic acid	IC50	1100000.0 [1], 1600000.0 [2]
	2-[(2S)-1-[(2S)-2-Aminopropanoyl]pyrrolidine-2-carbonyl]oxyacetic acid	IC50	290000.0 [1], 370000.0 [2]
	2-[(2S)-2-[[(2S)-2-[[(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]oxyacetic acid	IC50	2000.0 [1], 23000.0 [2]
	2-[(2S)-2-[[(2S)-2-Acetamido-4-methylpentanoyl]amino]-3-phenylpropanoyl]oxyacetic acid	IC50	3000.0 [1], 9000.0 [2]
	2-[(2S)-2-[[(2S)-2-[[(2S)-1-Acetylpyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]oxyacetic acid	IC50	6000.0 [1], 38000.0 [2]
	2-[(2S)-2-[[(2S)-2-[(2-Aminoacetyl)amino]propanoyl]amino]-3-phenylpropanoyl]oxyacetic acid	IC50	160000.0 [1], 560000.0 [2]
	2-[2-[[(2S)-2-Acetamido-4-methylpentanoyl]amino]acetyl]oxyacetic acid	IC50	120000.0 [1], 200000.0 [2]
	2-[(2S)-Pyrrolidine-2-carbonyl]oxyacetic acid	IC50	500000.0 [1], 600000.0 [2]
	2-[(2S)-1-[(2S)-2-[(2-Aminoacetyl)amino]propanoyl]pyrrolidine-2-carbonyl]oxyacetic acid	IC50	980000.0 [1], 1100000.0 [2]
	2-[(2S)-2-[[(2S)-2-Aminopropanoyl]amino]-3-phenylpropanoyl]oxyacetic acid	IC50	350000.0 [1], 370000.0 [2]
	2-(2-Acetamidoacetoxy)Acetic Acid	IC50	210000.0 [1], 1800000.0 [2]
	2-[2-[[(2S)-2-[(2S)-1-Acetylpyrrolidine-2-carbonyl]oxy-4-methylpentanoyl]amino]acetyl]oxyacetic acid	IC50	76000.0 [1], 180000.0 [2]
	2-[2-[[(2S)-2-[[(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]acetyl]oxyacetic acid	IC50	12000.0 [1], 71000.0 [2]
	N-Decanoylglycine	IC50	30000.0 [1], 110000.0 [2]
	trans-Styrylacetic acid	Ki	96.0 [1]
	2-(Styrylthio)acetic acid	Ki	0.1 [1]
	Phenylethynylsulfanyl-acetic acid	Ki	0.19 [1]
	Phenylacetic acid 2-oxo-2-hydroxyethyl ester	IC50	2000.0 [1]
	2-(2-Phenylacetyl)sulfanylacetic acid	IC50	45000.0 [1]
	2-[(2S)-2-Acetamido-3-phenylpropanoyl]sulfanylacetic acid	IC50	45000.0 [1]
	2-Dodecanoyloxyacetic acid	IC50	60.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 24 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Peptidyl-glycine alpha-amidating monooxygenase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/peptidyl-glycine-alpha-amidating-monooxygenase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ Peptidyl-glycine alpha-amidating monooxygenase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/peptidyl-glycine-alpha-amidating-monooxygenase-inhibitors-ic50-ki.
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