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Peptide deformylase mitochondrial Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
ActinoninIC501.5 [1], 10.0 [2], 600.0 [3], 2700.0 [4]
ActinoninKi0.3 [1]
2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid (1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amideIC507.0 [1]
N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamideIC5070.0 [1]
(2S)-2-[[(2R)-2-(Cyclohexylmethyl)-3-[formyl(hydroxy)amino]propanoyl]amino]-N,N,3,3-tetramethylbutanamideIC506.0 [1]
(2Z)-2-(3-Butyl-1,3-benzothiazol-2-ylidene)-N-hydroxyacetamideIC501040.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]heptanamideIC5010.0 [1]
(2S)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamideIC5070.0 [1]
N-(1-Benzenesulfonyl-5-bromo-2-methyl-1H-indol-3-ylmethyl)-N-hydroxyformamideIC50200000.0 [1]
3-Benzoyl-6,7-dichloro-1-benzofuran-4,5-dioneIC5045000.0 [1]
(S)-2-[(R)-2-Benzyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3,N,N-tetramethyl-butyramideIC5020.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]decanamideIC5050.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]nonanamideIC5040.0 [1]
(S)-2-[(R)-2-Cyclopentyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3,N,N-tetramethyl-butyramideIC5020.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]-5-methylhexanamideIC5020.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]-4-methylpentanamideIC5010.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]-3-methylbutanamideIC5050.0 [1]
(2S)-2-[[(2R)-2-(Ethylsulfanylmethyl)-3-[formyl(hydroxy)amino]propanoyl]amino]-N,N,3,3-tetramethylbutanamideIC5020.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hex-4-ynamideIC5030.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hex-5-enamideIC5020.0 [1]
(2S)-2-[[(2R)-2-[[Formyl(hydroxy)amino]methyl]pent-4-enoyl]amino]-N,N,3,3-tetramethylbutanamideIC5030.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[2-[formyl(hydroxy)amino]ethyl]hexanamideIC501000.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]pentanamideIC5050.0 [1]
(2S)-2-[[(2R)-2-[[Formyl(hydroxy)amino]methyl]-3-piperidin-1-ylpropanoyl]amino]-N,N,3,3-tetramethylbutanamideIC501000.0 [1]
(2S)-2-[[(2R)-2-[[Formyl(hydroxy)amino]methyl]-3-(4-methoxyphenyl)propanoyl]amino]-N,N,3,3-tetramethylbutanamideIC50200.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]octanamideIC5030.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[1-[formyl(hydroxy)amino]ethyl]hexanamideIC50600.0 [1]
(S)-2-[(R)-3-(Formyl-hydroxy-amino)-2-methyl-propionylamino]-3,3,N,N-tetramethyl-butyramideIC50100.0 [1]
2-[2-Oxo-2-(hydroxyamino)ethylidene]-3-butyl-2,3-dihydrobenzothiazole 1,1-dioxideIC50100000.0 [1]
3-Butyl-2,3-dihydrobenzothiazole-2-ylideneacetic acidIC50100000.0 [1]
(2Z)-N-Hydroxy-2-(3-pentyl-1,3-benzothiazol-2-ylidene)acetamideIC509910.0 [1]
(2Z)-2-(3-Ethyl-1,3-benzothiazol-2-ylidene)-N-hydroxyacetamideIC50100000.0 [1]
(2Z)-N-Hydroxy-2-(3-propyl-1,3-benzothiazol-2-ylidene)acetamideIC508390.0 [1]
2-[(2Z)-2-Amino-2-hydroxyiminoethyl]-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]hexanamideIC501000.0 [1]
2-[[(2S)-1-[[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]acetic acidIC501000.0 [1]
(R)-3-[[(S)-1-(Dimethylcarbamoyl)-2,2-dimethylpropyl]carbamoyl]heptanoic acid hydrazideIC50200.0 [1]
(R)-3-((S)-1-Dimethylcarbamoyl-2,2-dimethyl-propylcarbamoyl)-heptanoic acidIC50200.0 [1]
(2R)-2-[[Carbamoyl(hydroxy)amino]methyl]-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]hexanamideIC501000.0 [1]
(2R)-N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-(formamidomethyl)hexanamideIC501000.0 [1]
[2-((S)-1-Dimethylcarbamoyl-2,2-dimethyl-propylcarbamoyl)-hexyl]-phosphonic acidIC501000.0 [1]
[2-((S)-1-Dimethylcarbamoyl-2,2-dimethyl-propylcarbamoyl)-hexyl]-phosphinic acidIC501000.0 [1]
1-(5-Bromo-1H-indol-3-yl)-3-(hydroxyamino)propan-2-oneIC50360000.0 [1]
1-(4-Fluoro-1H-indol-3-yl)-3-(hydroxyamino)propan-2-oneIC50700000.0 [1]
2-(5-Chloro-1H-indol-3-yl)-N-hydroxyacetamideIC50600000.0 [1]
1-(6-Bromo-1H-indol-3-yl)-3-(hydroxyamino)propan-2-oneIC50250000.0 [1]
2-(5-Bromo-2-methyl-1H-indolyl)-N-hydroxyacetamideIC50450000.0 [1]
6,7-Dibromo-3-(3,4-dimethoxy-benzoyl)-benzofuran-4,5-dioneIC5010000.0 [1]
3-Benzoyl-benzofuran-4,5-dioneIC5059000.0 [1]
3-(4-Methoxy-benzoyl)-benzofuran-4,5-dioneIC5034000.0 [1]
7-Chloro-3-(4-methoxybenzoyl)-benzofuran-4,5-dioneIC5016000.0 [1]
6-Chloro-3-(4-methoxybenzoyl)-benzofuran-4,5-dioneIC5040000.0 [1]
6,7-Dichloro-3-(4-methoxy-benzoyl)-benzofuran-4,5-dioneIC5015000.0 [1]
7-Bromo-3-(4-methoxybenzoyl)-benzofuran-4,5-dioneIC5015000.0 [1]
6,7-Dibromo-3-(4-methoxybenzoyl)-1-benzofuran-4,5-dioneIC5065000.0 [1]
6,7-Dichloro-3-(3,4-dimethoxy-benzoyl)-benzofuran-4,5-dioneIC506100.0 [1]
6,7-Dichloro-3-(3,4,5-trimethoxy-benzoyl)-benzofuran-4,5-dioneIC5025000.0 [1]
6,7-Dibromo-3-(3,4,5-trimethoxybenzoyl)-1-benzofuran-4,5-dioneIC505200.0 [1]
6-Bromo-3-(4-methoxybenzoyl)-benzofuran-4,5-dioneIC5032000.0 [1]
(2S)-2-[[(2R)-2-(Cyclopentylmethyl)-3-[formyl(hydroxy)amino]propanoyl]amino]-N,N,3,3-tetramethylbutanamideIC508.0 [1]
(2S)-2-[[(2R)-2-(4-Chlorophenyl)-3-[formyl(hydroxy)amino]propanoyl]amino]-N,N,3,3-tetramethylbutanamideIC50500.0 [1]
(S)-2-{(R)-2-[(Formyl-hydroxy-amino)-methyl]-butyrylamino}-3,3,N,N-tetramethyl-butyramideIC5070.0 [1]
(R)-3-[[(S)-1-(Dimethylcarbamoyl)-2,2-dimethylpropyl]carbamoyl]heptanehydroximic acidIC501.0 [1]
(2S)-N-[(2S)-6-Amino-1-(4-nitroanilino)-1-oxohexan-2-yl]-2-(sulfanylmethyl)hexanamideKi19.0 [1]
2-[2-(Mercaptomethyl)hexanoylamino]-5-guanidinovaleric acid methyl esterKi2500.0 [1]
Items per page: 1 - 10 of 64
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References

This online tool may be cited as follows

MLA

"Quest Database™ Peptide deformylase mitochondrial Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/peptide-deformylase-mitochondrial-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Peptide deformylase mitochondrial Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/peptide-deformylase-mitochondrial-inhibitors-ic50-ki.
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