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Pantothenate kinase 3 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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3-(2,4-Dimethylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-3-yl)-N-(3-(methylthio)phenyl)propanamideIC5025.0 [1], 360.0 [2]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(3-methoxyphenyl)propanamideIC501640.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-[(4-methoxyphenyl)methyl]propanamideIC5025840.0 [1]
2-(2,3-Dichlorophenyl)-N-(3-methylbutyl)-1,3-thiazole-4-carboxamideIC502450.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(4-methylsulfanylphenyl)propanamideIC5010510.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-phenylpropanamideIC5024500.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-methyl-N-phenylpropanamideIC5056000.0 [1]
N-(Cyclohexylmethyl)-3-(4,6-dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)propanamideIC5040890.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(4-methylphenyl)propanamideIC5025560.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(2-fluorophenyl)propanamideIC5013640.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-[(4-fluorophenyl)methyl]propanamideIC5056000.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-[(3-fluorophenyl)methyl]propanamideIC5010050.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-[(3-methoxyphenyl)methyl]propanamideIC5056000.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-[3-(trifluoromethyl)phenyl]propanamideIC50830.0 [1]
Methyl 3-[3-(4,6-dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)propanoylamino]benzoateIC5056000.0 [1]
N-Cyclohexyl-3-(4,6-dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)propanamideIC5056000.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(2-methoxyphenyl)propanamideIC5056000.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(3-methylphenyl)propanamideIC503840.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(4-fluorophenyl)propanamideIC5056000.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(4-methoxyphenyl)propanamideIC5011290.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(3-fluorophenyl)propanamideIC50620.0 [1]
3-(12-Oxo-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9-trien-10-yl)-N-(4-propan-2-ylphenyl)propanamideIC50120.0 [1]
N-(Bicyclo[2.2.1]hept-2-yl)-4-[(ethylsulfonyl)amino]benzamideIC50180.0 [1]
N-(4-Acetamidophenyl)-3-(4,6-dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)propanamideIC50350.0 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Pantothenate kinase 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/pantothenate-kinase-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Pantothenate kinase 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/pantothenate-kinase-3-inhibitors-ic50-ki.
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