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Pantothenate kinase 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
3-(2,4-Dimethylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-3-yl)-N-(3-(methylthio)phenyl)propanamideIC5070.0 [1], 140.0 [2]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(3-methoxyphenyl)propanamideIC50280.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-[(4-methoxyphenyl)methyl]propanamideIC5014690.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(4-methylsulfanylphenyl)propanamideIC503240.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-phenylpropanamideIC50850.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-methyl-N-phenylpropanamideIC5056000.0 [1]
N-(Cyclohexylmethyl)-3-(4,6-dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)propanamideIC501220.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(4-methylphenyl)propanamideIC5011160.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(2-fluorophenyl)propanamideIC50550.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-[(4-fluorophenyl)methyl]propanamideIC5056000.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-[(3-fluorophenyl)methyl]propanamideIC5015780.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-[(3-methoxyphenyl)methyl]propanamideIC5056000.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-[3-(trifluoromethyl)phenyl]propanamideIC50190.0 [1]
Methyl 3-[3-(4,6-dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)propanoylamino]benzoateIC5056000.0 [1]
N-Cyclohexyl-3-(4,6-dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)propanamideIC5013610.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(2-methoxyphenyl)propanamideIC5056000.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(3-methylphenyl)propanamideIC501570.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(4-fluorophenyl)propanamideIC5056000.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(4-methoxyphenyl)propanamideIC506690.0 [1]
3-(4,6-Dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)-N-(3-fluorophenyl)propanamideIC50240.0 [1]
N-(4-Acetamidophenyl)-3-(4,6-dimethyl-3,7,8,10-tetrazatricyclo[7.4.0.02,7]trideca-1,3,5,8,10,12-hexaen-5-yl)propanamideIC50640.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Pantothenate kinase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/pantothenate-kinase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Pantothenate kinase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/pantothenate-kinase-1-inhibitors-ic50-ki.
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