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ORAI 1/2/3 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
DiphenhydramineIC50500000.0 [1]
DiphenylmethanolIC50500000.0 [1]
Methylboronic acidIC50500000.0 [1]
Diphenylborinic acidIC508700.0 [1], 9800.0 [2]
Diphenylborinic anhydrideIC5011400.0 [1], 13400.0 [2]
Hydroxydip-tolylboraneIC5023000.0 [1], 25900.0 [2]
2-BenzhydryloxyethanamineIC50106000.0 [1], 184200.0 [2]
Bis(4-fluorophenyl)borinic AcidIC5017100.0 [1], 26600.0 [2]
Bis[4-(trifluoromethyl)phenyl]borinic acidIC507600.0 [1], 9500.0 [2]
9,9-Diphenyl-8-oxa-1-azonia-9-boranuidabicyclo[4.3.0]nona-1,3,5-trieneIC5010200.0 [1], 10700.0 [2]
11-Hydroxy-5,6-dihydrobenzo[b][1]benzoborepineIC5033300.0 [1], 36400.0 [2]
3,3-Dimethyl-2,2-diphenyl-1-oxa-3-azonia-2-boranuidacyclopentaneIC505100.0 [1], 8900.0 [2]
2,2-Diphenyl-1-oxa-3-azonia-2-boranuidacyclohexaneIC507900.0 [1], 8200.0 [2]
CID 71660034IC5011800.0 [1], 13200.0 [2]
1,1-Diphenyl-2-oxa-8-aza-5-azonia-1-boranuidaspiro[4.5]decaneIC502200.0 [1], 6000.0 [2]
(4-Chlorophenyl)(hydroxy)(phenyl)boraneIC506400.0 [1], 21800.0 [2]
2,2-Diphenyl-1-oxa-3-aza-2-boranuidacyclopentaneIC5011900.0 [1], 22900.0 [2]
2,2-Diphenyl-1-oxa-3-aza-2-boranuidacyclopentan-5-oneIC5011000.0 [1], 38600.0 [2]
(4S)-4-(Hydroxymethyl)-2,2-diphenyl-1-oxa-3-aza-2-boranuidacyclopentan-5-oneIC509800.0 [1], 40500.0 [2]
2,2-Bis(4-fluorophenyl)-1-oxa-3-aza-2-boranuidacyclopentaneIC505900.0 [1], 9000.0 [2]
(5S)-2,2-Diphenyl-3-oxa-1-aza-2-boranuidabicyclo[3.3.0]octaneIC508900.0 [1], 10200.0 [2]
(5R)-2,2-Diphenyl-3-oxa-1-aza-2-boranuidabicyclo[3.3.0]octaneIC508000.0 [1], 10100.0 [2]
(4S)-4-(1H-Indol-3-ylmethyl)-2,2-diphenyl-1-oxa-3-aza-2-boranuidacyclopentan-5-oneIC506900.0 [1], 14700.0 [2]
2,2-Diphenyl-1-thia-3-aza-2-boranuidacyclopentaneIC5044600.0 [1], 51800.0 [2]
2,2-Bis(4-methylphenyl)-1-oxa-3-aza-2-boranuidacyclopentaneIC501600.0 [1], 7400.0 [2]
2,2-Bis(2-methoxyphenyl)-1-oxa-3-aza-2-boranuidacyclopentaneIC5010500.0 [1], 11600.0 [2]
2,2-Bis[4-(trifluoromethyl)phenyl]-1-oxa-3-aza-2-boranuidacyclopentaneIC502100.0 [1], 3200.0 [2]
2,2-Bis(4-methoxyphenyl)-1-oxa-3-aza-2-boranuidacyclopentaneIC5012400.0 [1], 25800.0 [2]
2-(4-Fluorophenyl)-2-phenyl-1-oxa-3-aza-2-boranuidacyclopentaneIC509300.0 [1], 9800.0 [2]
2-(2-Methylphenyl)-2-phenyl-1-oxa-3-aza-2-boranuidacyclopentaneIC509900.0 [1], 10000.0 [2]
2-(4-Methylphenyl)-2-phenyl-1-oxa-3-aza-2-boranuidacyclopentaneIC502700.0 [1], 8600.0 [2]
2-(4-Butylphenyl)-2-phenyl-1-oxa-3-aza-2-boranuidacyclopentaneIC502400.0 [1], 3500.0 [2]
2-(5-Methylthiophen-2-yl)-2-phenyl-1-oxa-3-aza-2-boranuidacyclopentaneIC5025200.0 [1], 30900.0 [2]
2-(4-Bromophenyl)-2-phenyl-1-oxa-3-aza-2-boranuidacyclopentaneIC503400.0 [1], 4900.0 [2]
2-(4-Iodophenyl)-2-phenyl-1-oxa-3-aza-2-boranuidacyclopentaneIC502800.0 [1], 7200.0 [2]
2-Phenyl-2-(4-phenylphenyl)-1-oxa-3-aza-2-boranuidacyclopentaneIC507700.0 [1], 13400.0 [2]
Items per page: 1 - 10 of 36
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References

This online tool may be cited as follows

MLA

"Quest Database™ ORAI 1/2/3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/orai-1-2-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ ORAI 1/2/3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/orai-1-2-3-inhibitors-ic50-ki.
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