Opioid receptors; mu & delta Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Morphine	IC50	309.0 [1]
	Naltrexone	Ki	0.02 [1]
	Damgo	IC50	76.1 [1]
	Dpdpe	IC50	2.5 [1]
	Naltrindole	Ki	31.5 [1]
	Dslet	IC50	0.4 [1]
	(2S)-1-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2R)-1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide	IC50	3333.0 [1]
	(2S)-2-Amino-3-(4-hydroxyphenyl)-N-[(2R)-1-[[2-(4-methylpentan-2-ylamino)-2-oxoethyl]amino]-1-oxopropan-2-yl]propanamide	IC50	1050.0 [1]
	(2S)-2-Amino-3-(4-hydroxyphenyl)-N-[(2S)-1-[[2-(4-methylpentan-2-ylamino)-2-oxoethyl]amino]-1-oxopropan-2-yl]propanamide	IC50	50000.0 [1]
	(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R,3R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoic acid	IC50	0.15 [1]
	(1S,2R,13R)-13,22-Dimethyl-2-[(E)-3-phenylprop-2-enyl]-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5,7,9,15,17,19(25)-heptaen-16-ol	Ki	3.5 [1]
	2-Amino-3-(4-hydroxy-phenyl)-N-(1-{[(3-methyl-butylcarbamoyl)-methyl]-carbamoyl}-ethyl)-propionamide	IC50	3410.0 [1]
	2-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid	IC50	36.9 [1]
	2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-methyl-N-[2-(4-methylpentan-2-ylamino)-2-oxoethyl]propanamide	IC50	4720.0 [1]
	(2S)-2-Amino-N-[(2R)-3-hydroxy-1-[[2-(4-methylpentan-2-ylamino)-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide	IC50	990.0 [1]
	(2S)-2-Amino-3-(4-hydroxyphenyl)-N-[(2R)-1-[[2-(4-methylpentan-2-ylamino)-2-oxoethyl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]propanamide	IC50	105.0 [1]
	(2S)-2-Amino-N-[(2R)-1-[[2-[ethyl(4-methylpentan-2-yl)amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide	IC50	1800.0 [1]
	(2R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-N-[2-(3-methylbutylamino)-2-oxoethyl]-4-methylsulfanylbutanamide	IC50	733.0 [1]
	(2S)-2-[[2-[[(2R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]-methylamino]-N-(2-hydroxyethyl)-4-methylpentanamide	IC50	3180.0 [1]
	(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoic acid	IC50	2.45 [1]
	(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R,3R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-methylamino]-4-methylpentanoyl]amino]-3-hydroxybutanoic acid	IC50	1.33 [1]
	(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R,3R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoic acid	IC50	0.25 [1]
	(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R,3R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoic acid	IC50	0.41 [1]
	(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[2-[[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]carbamoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoic acid	IC50	38.0 [1]
	(2R)-2-[5-[[2-[[(3R)-2-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]acetyl]amino]pentanoylamino]-6-[5-[[2-[[(2R)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-naphthalen-1-ylpropanoyl]amino]acetyl]amino]pentanoylamino]hexanoic acid	IC50	153.0 [1]
	(1S,10S,14S,18E)-18-Benzylidene-3-hydroxy-4-methoxy-17-methyl-17-azapentacyclo[7.5.3.210,14.01,10.02,7]nonadeca-2(7),3,5-trien-13-one	Ki	0.08 [1]
	(1S,2R,13R)-13,22-Dimethyl-2-(3-methylbut-2-enyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5,7,9,15,17,19(25)-heptaen-16-ol	Ki	4.9 [1]
	(1S,2S,13R)-19-Methoxy-24-methyl-26-propan-2-ylidene-4,24-diazaheptacyclo[12.7.3.22,13.01,13.03,11.05,10.016,21]hexacosa-3(11),5,7,9,16(21),17,19-heptaen-20-ol	Ki	3.2 [1]
	(1S,10S,14S,18E)-3-Hydroxy-4-methoxy-17-methyl-18-(1-phenylethylidene)-17-azapentacyclo[7.5.3.210,14.01,10.02,7]nonadeca-2(7),3,5-trien-13-one	Ki	0.8 [1]
	(1S,2S,13R,26E)-26-Benzylidene-19-methoxy-24-methyl-4,24-diazaheptacyclo[12.7.3.22,13.01,13.03,11.05,10.016,21]hexacosa-3(11),5,7,9,16(21),17,19-heptaen-20-ol	Ki	0.4 [1]
	(1S,2S,13R,26E)-19-Methoxy-24-methyl-26-(1-phenylethylidene)-4,24-diazaheptacyclo[12.7.3.22,13.01,13.03,11.05,10.016,21]hexacosa-3(11),5,7,9,16(21),17,19-heptaen-20-ol	Ki	0.6 [1]
	(1S,2S,13R,26E)-26-Ethylidene-19-methoxy-24-methyl-4,24-diazaheptacyclo[12.7.3.22,13.01,13.03,11.05,10.016,21]hexacosa-3(11),5,7,9,16(21),17,19-heptaen-20-ol	Ki	1.5 [1]
	(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2R,3R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]-methylamino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoic acid	IC50	7.3 [1]
	(2S,3R)-2-[[(1S)-1-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-methylbutyl]amino]-3-hydroxybutanoic acid	IC50	3.45 [1]
	(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]acetyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoic acid	IC50	13.0 [1]
	(2S,4R)-1-[(2S)-2-[[(2S)-2-[[2-[[(2R,3S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]-4-hydroxypyrrolidine-2-carboxylic acid	IC50	1.1 [1]
	(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,3S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypentanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoic acid	IC50	0.05 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 37 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Opioid receptors; mu & delta Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/opioid-receptors-mu-delta-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 22). Quest Database™ Opioid receptors; mu & delta Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/opioid-receptors-mu-delta-inhibitors-ic50-ki.
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