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Nucleotide-binding oligomerization domain-containing protein 2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Nodinitib-1IC5020000.0 [1]
1-(4-Chlorophenyl)sulfonyl-2-benzimidazolamineIC5019900.0 [1]
Ethyl 4-[[4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)benzoyl]amino]benzoateIC50400.0 [1]
Cyclopropyl-[5-[4-(4-methoxyphenyl)piperazino]sulfonyl-2-methyl-indolin-1-yl]methanoneIC50390.0 [1]
1-(4-Chlorophenylmethyl)-2-aminobenzimidazoleIC5011900.0 [1]
1-[5-[4-(4-Chlorophenyl)piperazino]sulfonyl-2-methyl-indolin-1-yl]propan-1-oneIC50600.0 [1]
Cyclopropyl-[2-methyl-5-[4-(4-nitrophenyl)piperazino]sulfonyl-indolin-1-yl]methanoneIC50200.0 [1]
CID 44182149IC50260.0 [1]
CID 44229055IC5030.0 [1]
PaclitaxelIC507943.28 [1]
DocetaxelIC505011.87 [1]
1-(Toluene-4-sulfonyl)-1H-benzoimidazoleIC5020000.0 [1]
1-[4-[4-(1-Acetyl-2-methyl-indolin-5-yl)sulfonylpiperazino]phenyl]ethanoneIC503720.0 [1]
2-Methyl-1-(4-methylphenyl)sulfonylbenzimidazoleIC5020000.0 [1]
(2-Aminobenzimidazol-1-yl)-(4-fluorophenyl)methanoneIC5020000.0 [1]
4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-N-p-tolyl-benzamideIC5020000.0 [1]
N-(4-Chloro-phenyl)-4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-benzamideIC503540.0 [1]
4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-ethoxy-phenyl)-benzamideIC50570.0 [1]
4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-fluoro-phenyl)-benzamideIC501850.0 [1]
2-Methyl-5-{[4-(4-nitrophenyl)piperazin-1-yl]sulfonyl}-1-propionylindolineIC501550.0 [1]
CID 20901603IC503630.0 [1]
Cyclopropyl-[2-methyl-5-(4-phenylpiperazino)sulfonyl-indolin-1-yl]methanoneIC5017400.0 [1]
1-[4-[4-[1-(Cyclopropanecarbonyl)-2-methyl-indolin-5-yl]sulfonylpiperazino]phenyl]ethanoneIC507900.0 [1]
7-[(E)-But-2-enyl]-3-methyl-8-(3-phenylpropylsulfanyl)purine-2,6-dioneIC5012700.0 [1]
3-Methyl-7-pentyl-8-(2-phenylethylthio)purine-2,6-dioneIC5020000.0 [1]
3-Methyl-7-(phenylmethyl)-8-(propan-2-ylthio)purine-2,6-dioneIC5018100.0 [1]
7-Benzyl-3-methyl-8-nitropurine-2,6-dioneIC50750.0 [1]
1-(Phenylsulfonyl)-1H-benzimidazol-2-amineIC5020000.0 [1]
1-((4-Nitrophenyl)sulfonyl)-1H-benzimidazol-2-amineIC5020000.0 [1]
1-(4-Methoxyphenyl)sulfonyl-2-benzimidazolamineIC5020000.0 [1]
5,6-Dimethyl-1-(4-methylphenyl)sulfonyl-2-benzimidazolamineIC5020000.0 [1]
1-(2-Aminobenzimidazol-1-yl)-2-phenylethanoneIC5020000.0 [1]
4-(3,4-Dihydroisoquinolin-2(1H)-ylmethyl)-N-(4-methoxyphenyl)benzamideIC50780.0 [1]
1-Acetyl-5-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}-2-methylindolineIC503290.0 [1]
(2-Aminobenzimidazol-1-yl)-(2,4-dichlorophenyl)methanoneIC503800.0 [1]
N-(4-Bromophenyl)-4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)benzamideIC501620.0 [1]
1-Pentyl-4-phenylmethoxybenzimidazol-2-amineIC5010000.0 [1]
4-Benzyl-1-pentylbenzimidazol-2-amineIC5010000.0 [1]
3-Pentylbenzo[f]benzimidazol-2-amineIC5010000.0 [1]
1-Pentylbenzo[e]benzimidazol-2-amineIC5010000.0 [1]
N-(1-Pentylbenzimidazol-2-yl)acetamideIC5010000.0 [1]
1-Pentyl-4-phenylbenzimidazol-2-amineIC5010000.0 [1]
Methyl 3-[(3S)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[[2-[[4-(trifluoromethyl)phenyl]methoxy]acetyl]amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC50590.0 [1]
Methyl 3-[(3R)-7-[3-(dimethylamino)phenoxy]-8-[[2-[(3-fluorophenyl)methoxy]acetyl]amino]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC504020.0 [1]
Methyl 3-[(3R)-8-[[2-[(4-bromophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501190.0 [1]
Methyl 3-[(3R)-7-[3-(dimethylamino)phenoxy]-8-[[2-(naphthalen-2-ylmethoxy)acetyl]amino]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501580.0 [1]
Methyl 3-[(3R)-7-[4-chloro-3-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC503550.0 [1]
3-[(3R)-7-[3-(Dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]-N-propylpropanamideIC504160.0 [1]
N,N-Dibutyl-3-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanamideIC501320.0 [1]
N-[(3R)-7-[3-(Dimethylamino)phenoxy]-2,5-dioxo-3-(3-oxo-3-pyrrolidin-1-ylpropyl)-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]-2-phenylmethoxyacetamideIC503790.0 [1]
Methyl 3-[(3R)-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-7-[2,4,5-trichloro-3-(dimethylamino)phenoxy]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC503780.0 [1]
Methyl 3-[(3R)-8-[[2-[(3-chlorophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC502080.0 [1]
Methyl 3-[(3R)-8-[[2-[(4-cyanophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC502510.0 [1]
N-Butyl-3-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanamideIC502880.0 [1]
N-Cyclopropyl-3-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanamideIC507140.0 [1]
Methyl 3-[(3R)-8-[[2-[(4-chlorophenyl)methoxy]acetyl]amino]-2,5-dioxo-7-(3-pyrrolidin-1-ylphenoxy)-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501500.0 [1]
2-[(4-Chlorophenyl)methoxy]-N-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3-(3-oxo-3-piperidin-1-ylpropyl)-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]acetamideIC50900.0 [1]
3-[(3R)-7-[3-(Dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]-N,N-diethylpropanamideIC503410.0 [1]
Methyl 3-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[[2-[[4-(trifluoromethyl)phenyl]methoxy]acetyl]amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC50870.0 [1]
N-[(3S)-7-[3-(Dimethylamino)phenoxy]-3-methyl-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamideIC50940.0 [1]
N-[(3R)-7-[3-(Dimethylamino)phenoxy]-2,5-dioxo-3-(3-oxo-3-piperidin-1-ylpropyl)-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]-2-phenylmethoxyacetamideIC502990.0 [1]
Methyl 3-[(3R)-7-[3-(dimethylamino)phenoxy]-8-[[2-[(4-fluorophenyl)methoxy]acetyl]amino]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC503100.0 [1]
N-[(3R)-3-[3-(4,4-Difluoropiperidin-1-yl)-3-oxopropyl]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamideIC50810.0 [1]
N-Tert-butyl-3-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanamideIC502270.0 [1]
Methyl 3-[(3R)-7-[4-chloro-3-(dimethylamino)phenoxy]-8-[[2-[(4-chlorophenyl)methoxy]acetyl]amino]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501020.0 [1]
Methyl 3-[(3R)-8-[[2-[(4-tert-butylphenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC502390.0 [1]
Methyl 3-[(3R)-7-[3-chloro-5-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC505050.0 [1]
Methyl 3-[(3R)-8-[[2-[(3-bromophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC502280.0 [1]
Methyl 3-[(3R)-7-[3-(dimethylamino)phenoxy]-8-[[2-[(4-methoxyphenyl)methoxy]acetyl]amino]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC509510.0 [1]
Methyl 3-[(3R)-8-[[2-[(3,4-difluorophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501700.0 [1]
Methyl 3-[(3R)-8-[[2-[(4-chlorophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501240.0 [1]
N-[(3R)-7-[3-(Dimethylamino)phenoxy]-3-[3-(4-fluoropiperidin-1-yl)-3-oxopropyl]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamideIC50420.0 [1]
1-[4-[4-(1-Acetylindolin-5-yl)sulfonylpiperazino]phenyl]ethanoneIC5020000.0 [1]
1-[5-[4-(4-Acetylphenyl)piperazino]sulfonylindolin-1-yl]propan-1-oneIC5020000.0 [1]
1-Acetyl-5-{[4-(4-chlorophenyl)piperazin-1-yl]sulfonyl}-2-methylindolineIC501750.0 [1]
5-{[4-(4-Chlorophenyl)piperazin-1-yl]sulfonyl}-1-propionylindolineIC5020000.0 [1]
N-(4-Methoxyphenyl)-4-(piperidin-1-ylmethyl)benzamideIC5020000.0 [1]
1-[2-Methyl-5-(4-phenylpiperazino)sulfonyl-indolin-1-yl]ethanoneIC508270.0 [1]
1-[4-[4-[1-(Cyclopropanecarbonyl)indolin-5-yl]sulfonylpiperazino]phenyl]ethanoneIC5020000.0 [1]
1-[5-[4-(4-Nitrophenyl)piperazino]sulfonylindolin-1-yl]ethanoneIC5020000.0 [1]
N-(4-Ethoxyphenyl)-4-(piperidin-1-ylmethyl)benzamideIC5020000.0 [1]
N-(4-Fluorophenyl)-4-(piperidin-1-ylmethyl)benzamideIC5020000.0 [1]
CID 42370913IC5020000.0 [1]
CID 44182107IC5020000.0 [1]
CID 44182108IC5020000.0 [1]
1-[2-Methyl-5-[4-(4-nitrophenyl)piperazino]sulfonyl-indolin-1-yl]ethanoneIC501410.0 [1]
1-[5-[4-(4-Acetylphenyl)piperazino]sulfonyl-2-methyl-indolin-1-yl]propan-1-oneIC501580.0 [1]
1-[2-Methyl-5-[4-(p-tolyl)piperazino]sulfonyl-indolin-1-yl]ethanoneIC503450.0 [1]
Cyclopropyl-[2-methyl-5-[4-(p-tolyl)piperazino]sulfonyl-indolin-1-yl]methanoneIC5020000.0 [1]
CID 44182148IC5020000.0 [1]
CID 44182150IC5020000.0 [1]
CID 44229052IC5020000.0 [1]
CID 44229053IC503580.0 [1]
CID 44229054IC5020000.0 [1]
CID 44229056IC5020000.0 [1]
Ethyl 4-[[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]benzoyl]amino]benzoateIC5020000.0 [1]
4-[[4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)benzoyl]amino]benzenesulfonic acidIC5020000.0 [1]
CID 44229059IC5020000.0 [1]
4-[4-(1-Propionylindolin-5-yl)sulfonylpiperazino]benzonitrileIC5020000.0 [1]
[5-[4-(4-Chlorophenyl)piperazino]sulfonylindolin-1-yl]-cyclopropyl-methanoneIC5020000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Nucleotide-binding oligomerization domain-containing protein 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Dec. 2024, https://www.aatbio.com/data-sets/nucleotide-binding-oligomerization-domain-containing-protein-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 20). Quest Database™ Nucleotide-binding oligomerization domain-containing protein 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nucleotide-binding-oligomerization-domain-containing-protein-2-inhibitors-ic50-ki.
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