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Nuclear factor NF-kappa-B p65 subunit Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
RocaglamideIC5070.0 [1], 75.0 [2], 80.0 [3], 4000.0 [4]
alpha-MangostinIC5010000.0 [1], 15900.0 [2]
ResveratrolIC5020000.0 [1]
Oleanolic acidIC502400.0 [1]
Ursolic acidIC5031.0 [1]
Betulinic acidIC5010000.0 [1]
(E)-3-TosylacrylonitrileIC503000.0 [1]
BetulinIC508800.0 [1]
SilvestrolIC5020000.0 [1]
UvaolIC5010000.0 [1]
ErythrodiolIC5010000.0 [1]
5Z-7-OxozeaenolIC50250.0 [1]
LoliolideIC5010000.0 [1]
Combretum caffrumIC501600.0 [1]
4-DimethylaminostilbeneIC50150.0 [1]
5E-7-OxozeaenolIC5011500.0 [1]
Incensole acetateIC50100000.0 [1]
VomifoliolIC5010000.0 [1]
GartaninIC5019000.0 [1]
CycloartobiloxanthoneIC5010000.0 [1]
Alphitolic acidIC508700.0 [1]
8-(4-Benzenesulfonylamino)quinolineIC5010000.0 [1]
8-DesoxygartaninIC5011300.0 [1]
9-HydroxycalabaxanthoneIC5020000.0 [1]
SideroxylinIC5010000.0 [1]
beta-MangostinIC5012100.0 [1]
Garcinone DIC503200.0 [1]
5H-Quinolino[8,7-c][1,2]benzothiazine 6,6-dioxideIC501000.0 [1]
4-Methyl-2-nitro-N-quinolin-8-ylbenzenesulfonamideIC502100.0 [1]
(E)-3,4'-DimethoxystilbeneIC50600.0 [1]
2-Nitro-N-quinolin-8-ylbenzenesulfonamideIC503200.0 [1]
(4S,9S,10S,12E)-9,10,18-Trihydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dioneIC5050000.0 [1]
1,3,7-Trihydroxy-2,4-diisoprenylxanthoneIC502900.0 [1]
2-Amino-N-quinolin-8-yl-benzenesulfonamideIC502000.0 [1]
4-Nitro-N-(8-quinolyl)benzenesulfonamideIC501500.0 [1]
ArtobiloxanthoneIC503700.0 [1]
ZeaenolIC5050000.0 [1]
(2E)-1-(3-Bromophenyl)-3-(4-methoxyphenyl)prop-2-en-1-oneIC5050000.0 [1]
3,4-Dihydroxy-4'-methoxystilbeneIC50600.0 [1]
Cochinchinone AIC5010000.0 [1]
2'''-EpisilvestrolIC5020000.0 [1]
Nik smi1IC5020000.0 [1]
NF-kB Activation Inhibitor IVIC50150.0 [1]
3,6-DimethylmangostinIC5010000.0 [1]
Di-O-acetylmangostinIC5010000.0 [1]
(1R,3As,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]oxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acidIC505400.0 [1]
N-(3-(4-(3-Aminopropylamino)butylamino)propyl)dodecane-1-sulfonamideIC50340.0 [1]
(1)Benzopyrano(5,4,3-cde)(1,3)dioxolo(4,5-h)(1)benzopyran-5,11-dione, 1,2,3-trimethoxy-IC5010000.0 [1]
(1R,3As,5aS,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-3a-methoxycarbonyl-5b,8,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-5a-carboxylic acidIC501500.0 [1]
1-Chloro-2-[(E)-2-(4-methoxyphenyl)ethenyl]benzeneIC501500.0 [1]
3-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-5-methoxy-phenolIC5010000.0 [1]
N-(3-(4-(3-Aminopropylamino)butylamino)propyl)hexadecane-1-sulfonamideIC50230.0 [1]
N-(3-(4-(3-Aminopropylamino)butylamino)propyl)decane-1-sulfonamideIC50310.0 [1]
N-(3-(4-(3-Aminopropylamino)butylamino)propyl)octadecane-1-sulfonamideIC502100.0 [1]
N-(2-Methylquinolin-8-yl)-2-nitrobenzenesulfonamideIC503800.0 [1]
2-Amino-N-(2-methylquinolin-8-yl)benzenesulfonamideIC502800.0 [1]
N-(2-Methylquinolin-8-yl)-2-nitro-4-(trifluoromethyl)benzenesulfonamideIC501100.0 [1]
3-Methyl-9-(trifluoromethyl)-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxideIC501200.0 [1]
5-Bromo-N-(2-methylquinolin-8-yl)thiophene-2-sulfonamideIC501400.0 [1]
9-Trifluoromethyl-5H-6-thia-4,5-diaza-chrysene 6,6-dioxideIC501000.0 [1]
3-Methyl-6,6-dioxo-5H-quinolino[8,7-c][1,2]benzothiazin-9-olIC5010000.0 [1]
2-Amino-N-(6-methoxyquinolin-8-yl)-4-methylbenzenesulfonamideIC501000.0 [1]
2-Nitro-N-quinolin-8-yl-4-(trifluoromethyl)benzenesulfonamideIC503700.0 [1]
9-Fluoro-5H-6-thia-4,5-diaza-chrysene 6,6-dioxideIC501700.0 [1]
9-Methyl-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxideIC50600.0 [1]
9-Methoxy-3-methyl-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxideIC502500.0 [1]
9-Chloro-5H-6-thia-4,5-diaza-chrysene 6,6-dioxideIC501100.0 [1]
11-Methoxy-3,9-dimethyl-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxideIC50900.0 [1]
N-(2-Methylquinolin-8-yl)-3-nitrobenzenesulfonamideIC50900.0 [1]
5-Chloro-N-(2-methylquinolin-8-yl)thiophene-2-sulfonamideIC501000.0 [1]
9-Methoxy-5H-6-thia-4,5-diaza-chrysene 6,6-dioxideIC501000.0 [1]
N-(6-Methoxyquinolin-8-yl)-4-methyl-2-nitrobenzenesulfonamideIC502100.0 [1]
11-Methoxy-9-methyl-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxideIC501200.0 [1]
(E)-4-EthoxystilbeneIC50300.0 [1]
5-Bromo-N-quinolin-8-ylthiophene-2-sulfonamideIC501100.0 [1]
1-Fluoro-3-[(E)-2-(4-methoxyphenyl)ethenyl]benzeneIC501100.0 [1]
2-Methoxy-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxideIC502500.0 [1]
4-Methoxy-N-(2-methylquinolin-8-yl)-2-nitrobenzenesulfonamideIC501000.0 [1]
Artorigidin AIC502000.0 [1]
3,9-Dihydroxy-5,10-dimethoxy-2,2-dimethyl-11-(3-methylbut-2-enyl)-3,4-dihydropyrano[2,3-a]xanthen-12-oneIC5020000.0 [1]
5-Chloro-N-(quinolin-8-yl)thiophene-2-sulfonamideIC501300.0 [1]
5-Nitro-2-methyl-N-(8-quinolinyl)benzenesulfonamideIC501600.0 [1]
N-(Quinolin-8-yl)thiophene-2-sulfonamideIC503600.0 [1]
(1R,3As,5aR,5bR,7aR,9R,10R,11aR,11bR,13aR,13bR)-10-hydroxy-9-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acidIC504700.0 [1]
3-[(E)-2-(4-Methoxyphenyl)ethenyl]benzene-1,2-diolIC50500.0 [1]
(2S)-6-[(1R)-1-[2,4-Bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]phenyl]-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]propyl]-8-[(1S)-1-[2,4-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]phenyl]-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]propyl]-5,7-dihydroxy-2-[4-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-oneIC5019300.0 [1]
[1,6-Diacetyloxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)-9-oxoxanthen-3-yl] acetateIC5010000.0 [1]
(1S,2R,4As,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-(4-chlorobenzoyl)oxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acidIC5010000.0 [1]
(1R,3As,5aS,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a-(hydroxymethyl)-5b,8,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acidIC5010000.0 [1]
N-(6-Methoxy-2-methylquinolin-8-yl)-4-methylbenzenesulfonamideIC5010000.0 [1]
2-[(E)-2-Phenylethenyl]naphthaleneIC501300.0 [1]
(1R,3As,5aS,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5b,8,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a,5a-dicarboxylic acidIC5010000.0 [1]
Artoheterophyllin BIC5010000.0 [1]
3-Methyl-4'-methoxystilbeneIC50800.0 [1]
15-O-Desmethyl-(5Z)-7-oxozeaenolIC50750.0 [1]
ArtoristilbeneIC5010000.0 [1]
CratoxyxanthoneIC5020000.0 [1]
11-Hydroxy-1-isomangostinIC5020000.0 [1]
Artonin OIC5010000.0 [1]
(1R,2R,5S,8S,10R,11S,14R,15R,20S)-5-Hydroxy-8-(2-hydroxypropan-2-yl)-1,2,15,19,19-pentamethyl-9-oxapentacyclo[12.8.0.02,11.05,10.015,20]docosan-18-oneIC5020000.0 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Nuclear factor NF-kappa-B p65 subunit Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/nuclear-factor-nf-kappa-b-p65-subunit-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Nuclear factor NF-kappa-B p65 subunit Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nuclear-factor-nf-kappa-b-p65-subunit-inhibitors-ic50-ki.
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