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Nuclear factor NF-kappa-B p105 subunit Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
RocaglamideIC5075.0 [1], 2000.0 [2]
PsoralenIC503000.0 [1]
4-MethylumbelliferoneIC50200000.0 [1]
AndrographolideIC5049600.0 [1]
alpha-MangostinIC5020000.0 [1]
AngelicinIC502500.0 [1]
(1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-oneIC508200.0 [1]
2-Hydroxycinnamic acidIC5050000.0 [1]
CyqualonIC504400.0 [1]
GartaninIC5020000.0 [1]
CycloartobiloxanthoneIC5010000.0 [1]
N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5050.0 [1]
2-(4,5,6-Trihydroxy-3-oxoxanthen-9-yl)benzenesulfonic acidIC5010000.0 [1]
8-DesoxygartaninIC5020000.0 [1]
9-HydroxycalabaxanthoneIC5020000.0 [1]
beta-MangostinIC507500.0 [1]
(1E,4E)-1,5-Di(pyridin-3-yl)penta-1,4-dien-3-oneIC503400.0 [1]
Garcinone DIC5020000.0 [1]
3-(3-Fluoro-4-methoxyphenyl)-5-phenyl-7-furo[3,2-g][1]benzopyranoneIC5020000.0 [1]
2,4-Dichloro-6-(3-nitroanilino)-1,3,5-triazineIC50119000.0 [1]
2,4-Dichloro-6-(4-ethoxyanilino)-s-triazineIC5035200.0 [1]
ArtobiloxanthoneIC502300.0 [1]
1,5-Bis(2-hydroxyphenyl)penta-1,4-dien-3-oneIC504200.0 [1]
[4-[(1E,4E)-5-(4-Acetyloxy-3-methoxyphenyl)-3-oxopenta-1,4-dienyl]-2-methoxyphenyl] acetateIC505400.0 [1]
(1E,4E)-1,5-Bis(2,5-dimethoxyphenyl)penta-1,4-dien-3-oneIC506400.0 [1]
1,5-Bis[2-(trifluoromethyl)phenyl]-1,4-pentadiene-3-oneIC505000.0 [1]
3-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-5-methoxy-phenolIC5010000.0 [1]
8-(4-Methoxy-benzoyl)-4-methyl-9-phenyl-furo[2,3-h]chromen-2-oneIC5060000.0 [1]
[(1R,2R,4As,5R,8aS)-2-acetyloxy-1,4a-dimethyl-6-methylidene-5-[(2E)-2-(2-oxofuran-3-ylidene)ethyl]-3,4,5,7,8,8a-hexahydro-2H-naphthalen-1-yl]methyl acetateIC5011100.0 [1]
(4,6-Dichloro-[1,3,5]triazin-2-yl)-(4-isopropyl-phenyl)-amineIC5074400.0 [1]
Artorigidin AIC5010000.0 [1]
3,9-Dihydroxy-5,10-dimethoxy-2,2-dimethyl-11-(3-methylbut-2-enyl)-3,4-dihydropyrano[2,3-a]xanthen-12-oneIC5020000.0 [1]
2-(2,7-Dibromo-4,5,6-trihydroxy-3-oxoxanthen-9-yl)benzenesulfonic acidIC5030000.0 [1]
N-[3-(Butylcarbamoyl)-5-(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
2-Chloro-N-(3,4,5-trichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC50900.0 [1]
N-(3,5-Dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
2-Chloro-4-(trifluoromethyl)-N-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamideIC50380.0 [1]
2-Chloro-N-(3,5-dichlorophenyl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamideIC502300.0 [1]
2-(Cyclohexylamino)-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
N-[3-Carbamoyl-5-(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamideIC505000.0 [1]
N-Benzyl-2-chloro-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC502700.0 [1]
2-Anilino-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
N-(3,5-Dichlorophenyl)-2-(dimethylamino)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
Cyclohexyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoateIC501800.0 [1]
Hexyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoateIC50620.0 [1]
Diethoxyphosphorylmethyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoateIC504600.0 [1]
Butyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoateIC50170.0 [1]
N-(3,5-Dichlorophenyl)-2-methoxy-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
2-(Butylamino)-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
2-Chloro-N-(2,6-dimethylphenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
N-(3,5-Dichlorophenyl)-2-oxo-6-(trifluoromethyl)-1H-pyrimidine-5-carboxamideIC5010000.0 [1]
2-Chloro-N-(2,6-dichloropyrimidin-4-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC50800.0 [1]
N-(3,5-Dichlorophenyl)-2-piperidin-1-yl-4-(trifluoromethyl)pyrimidine-5-carboxamideIC505000.0 [1]
2-(Benzylamino)-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
2-Chloro-N-(3-methyl-1,2-oxazol-5-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC504000.0 [1]
2-Chloro-N-(5-methylthiophen-2-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC502300.0 [1]
2-Amino-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
2-Chloro-N-(3,5-dimethoxyphenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamideIC501200.0 [1]
Octyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoateIC501800.0 [1]
N-Butyl-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
Ethyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoateIC50280.0 [1]
(1E,4E)-1,5-Di(pyridin-4-yl)penta-1,4-dien-3-oneIC503500.0 [1]
(1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-4-methylhepta-1,4,6-trien-3-oneIC506700.0 [1]
2-((2-Methoxyethyl)amino)-6-methyl-3-(3,4,5-trimethoxyphenyl)-4H-furo[3,2-c]chromen-4-oneIC5040000.0 [1]
4,6-Dichloro-N-(4-chlorophenyl)-1,3,5-triazin-2-amineIC50110000.0 [1]
4,6-Dichloro-N-(4-nitrophenyl)-1,3,5-triazin-2-amineIC50300000.0 [1]
3-(1,3-Benzodioxol-5-yl)-5-phenyl-7H-furo[3,2-g]chromen-7-oneIC5020000.0 [1]
N5-(3,5-Dichlorophenyl)-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamideIC50500.0 [1]
2-Chloro-N-phenyl-4-(trifluoromethyl)pyrimidine-5-carboxamideIC5010000.0 [1]
Artoheterophyllin BIC5010000.0 [1]
ArtoristilbeneIC5010000.0 [1]
CratoxyxanthoneIC5020000.0 [1]
11-Hydroxy-1-isomangostinIC5020000.0 [1]
Artonin OIC5010000.0 [1]
4-[(7-Hydroxy-4-oxo-2,3-dihydro-1H-cyclopenta[c]chromen-9-yl)oxymethyl]benzoic acidIC505000.0 [1]
(4,6-Dichloro-[1,3,5]triazin-2-yl)-m-tolyl-amineIC5019000.0 [1]
(1E,4Z,6E)-4-Benzyl-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-oneIC507600.0 [1]
(1E,6E)-1-[4-Hydroxy-3-(hydroxymethyl)phenyl]-7-(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dioneIC508200.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Nuclear factor NF-kappa-B p105 subunit Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/nuclear-factor-nf-kappa-b-p105-subunit-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Nuclear factor NF-kappa-B p105 subunit Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nuclear-factor-nf-kappa-b-p105-subunit-inhibitors-ic50-ki.
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