NUAK family SNF1-like kinase 1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	4-[2-(Butylamino)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexan-1-ol	IC50	7.97 [1]
	Quercetin	IC50	5090.0 [1]
	Staurosporine	IC50	8.0 [1]
	Ellagic acid	IC50	510.0 [1]
	Palbociclib	IC50	5000.0 [1]
	Doramapimod	IC50	30000.0 [1]
	Norlichexanthone	IC50	33000.0 [1]
	CID 56649281	IC50	4.95 [1]
	3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione	IC50	43000.0 [1]
	(12E,25E,28E)-5,16,21,32-Tetrabromo-4,20-dihydroxy-12,25-bis(hydroxyimino)-2,18-dioxa-10,27-diazapentacyclo[28.2.2.214,17.13,7.119,23]octatriaconta-1(32),3,5,7(38),14,16,19,21,23(35),28,30,33,36-tridecaene-11,26-dione	IC50	3200.0 [1]
	(1S,2S,3R,4R)-3-[[5-Chloro-2-[[(7S)-4-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide	IC50	26.0 [1]
	2,3,6,8-Tetrahydroxy-1-methylxanthone	IC50	15600.0 [1]
	Epicoccolide B	IC50	3770.0 [1]
	4-[5-[4-[(4-Methyl-1,4-diazepan-1-yl)methyl]phenyl]-2-[[(2S)-pentan-2-yl]amino]pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexan-1-ol	IC50	100.0 [1]
	5-[6-(1-Methylpiperidin-4-yl)oxybenzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxamide	IC50	840.0 [1]
	Astrogorgiadiol B	IC50	100000.0 [1]
	(1S,9R)-5,6,12,13,14-Pentahydroxy-4,11-dimethyl-16-oxo-8,17-dioxatetracyclo[7.7.1.02,7.010,15]heptadeca-2(7),3,5,10,12,14-hexaene-3-carbaldehyde	IC50	2510.0 [1]
	(1R,3As,4S,5R,7aR)-4-[2-(5-hydroxy-2-methylphenyl)ethyl]-7a-methyl-1-[(2R)-6-methyl-5-methylideneheptan-2-yl]-1,2,3,3a,4,5,6,7-octahydroinden-5-ol	IC50	100000.0 [1]
	Calicoferol B	IC50	100000.0 [1]
	(2Z)-3-[3-Bromo-5-[3-bromo-5-[(2Z)-3-[2-(3-bromo-4-hydroxyphenyl)ethylamino]-2-hydroxyimino-3-oxopropyl]-2-hydroxyphenyl]-4-hydroxyphenyl]-N-[2-(3-bromo-4-hydroxyphenyl)ethyl]-2-hydroxyiminopropanamide	IC50	1800.0 [1]
	GSK 461364 analogue I	IC50	2000.0 [1]
	5-Propan-2-yl-7,8-dihydro-6H-indeno[1,2-b]indole-9,10-dione	IC50	35000.0 [1]
	7-Chloro-3-oxo-8-(1,3-thiazol-5-ylmethylamino)-11,16-dioxa-2,4,19,21-tetrazatricyclo[15.3.1.05,10]henicosa-1(20),5,7,9,17(21),18-hexaene-18-carbonitrile	Ki	1503.0 [1]
	Calicoferol E	IC50	100000.0 [1]
	4-(1-Methylindol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1,2-dihydropyrrol-5-one	IC50	4900.0 [1]
	1-[5-Tert-butyl-3-[4-[2-(dimethylamino)ethyl]-5-oxo-1,4-diazepane-1-carbonyl]thiophen-2-yl]-3-(2,3-dichlorophenyl)urea	IC50	30000.0 [1]
	6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one	IC50	10000.0 [1]
	2-Anilino-7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one	IC50	5.0 [1]
	(8S,16S)-3,16-Dihydroxy-9,10-seco-1,3,5(10)-cholestatrien-9-one	IC50	100000.0 [1]
	Calicoferol A	IC50	100000.0 [1]
	(1R,3As,4S,7aR)-4-[2-(5-hydroxy-2-methylphenyl)ethyl]-7a-methyl-1-[(2R)-6-methyl-5-methylideneheptan-2-yl]-2,3,3a,4,6,7-hexahydro-1H-inden-5-one	IC50	100000.0 [1]
	Methyl 3-[[(1R,2S,4aR,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]-4,5-dihydroxybenzoate	IC50	29400.0 [1]
	5-(1H-Indol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazin-2-one	IC50	100000.0 [1]
	3-[2-(4-Amino-1-ethylpyrazolo[3,4-d]pyrimidin-3-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide	IC50	10000.0 [1]
	4-[(4-Aminocyclohexyl)amino]-3-(1h-Benzimidazol-2-Yl)-1h-Pyridin-2-One	IC50	2.0 [1]
	Nintedanib impurity E	Ki	1.7 [1]
	Melk-IN-1	Ki	11.0 [1]
	2-Hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-5-carboxylic acid	Ki	8.6 [1]
	3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one	IC50	2000.0 [1]
	3-(N-Methyl-1H-indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one	IC50	3600.0 [1]
	4-(1H-Indol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1,2-dihydropyrrol-5-one	IC50	1800.0 [1]
	3-[1-(2,3-Dihydroxypropyl)indol-3-yl]-4-(3,4,5-trimethoxyphenyl)-1,2-dihydropyrrol-5-one	IC50	34000.0 [1]
	3-(12,14-Dioxo-10,13,16-triazahexacyclo[14.6.1.02,10.04,9.011,15.019,23]tricosa-1(22),2,4,6,8,11(15),17,19(23),20-nonaen-13-yl)propyl N'-methylcarbamimidothioate	IC50	9700.0 [1]
	(1R,3As,4S,5S,7aR)-4-[2-(5-hydroxy-2-methylphenyl)ethyl]-7a-methyl-1-[(E,2R)-6-methylhept-3-en-2-yl]-1,2,3,3a,4,5,6,7-octahydroinden-5-ol	IC50	100000.0 [1]
	(2E)-3-[3-Bromo-5-[3-bromo-5-[(2E)-3-[2-[3-bromo-4-[3-bromo-5-[(2E)-3-[2-(3-bromo-4-hydroxyphenyl)ethylamino]-2-hydroxyimino-3-oxopropyl]-2-hydroxyphenoxy]phenyl]ethylamino]-2-hydroxyimino-3-oxopropyl]-2-hydroxyphenyl]-4-hydroxyphenyl]-N-[2-(3-bromo-4-hydroxyphenyl)ethyl]-2-hydroxyiminopropanamide	IC50	1700.0 [1]
	5-Propan-2-yl-7,8-dihydroindeno[1,2-b]indole-6,9,10-trione	IC50	570.0 [1]
	5,6,7-Trihydroxy-3-methoxy-4-methyl-3H-2-benzofuran-1-one	IC50	29800.0 [1]
	3-[[(1R,2S,4Ar,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]-4-hydroxy-5-(3-methylbutylamino)cyclohexa-3,5-diene-1,2-dione	IC50	100000.0 [1]
	CID 76324771	IC50	30000.0 [1]
	4-Methyl-5,6,7-trihydroxy-1,3-dihydroisobenzofuran-1-one	IC50	10000.0 [1]
	7-[[(1R,2S,4Ar,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]-5-methoxy-2-methyl-1,3-benzoxazol-6-ol	IC50	100000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 51 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ NUAK family SNF1-like kinase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Dec. 2024, https://www.aatbio.com/data-sets/nuak-family-snf1-like-kinase-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 20). Quest Database™ NUAK family SNF1-like kinase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nuak-family-snf1-like-kinase-1-inhibitors-ic50-ki.
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