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Nicotinic acetylcholine receptor alpha3/betaX Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-phenylethynyl-pyridineIC50790.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-phenyl-pyridineIC505100.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-naphthalen-1-yl-pyridineIC50690.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-(2-pyridin-4-yl-ethyl)-pyridineIC506300.0 [1]
3-(4-Methoxy-phenyl)-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridineIC506970.0 [1]
3-Furan-2-yl-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridineIC507900.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-thiophen-2-yl-pyridineIC501700.0 [1]
3-[[(2S)-1-Methylpyrrolidin-2-yl]methoxy]-5-pyridin-3-ylpyridineIC5024700.0 [1]
3-(4-Fluoro-phenyl)-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridineIC506480.0 [1]
3-(4-Chloro-phenyl)-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridineIC501990.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-((E)-styryl)-pyridineIC504800.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-phenethyl-pyridineIC501100.0 [1]
3-Benzofuran-2-yl-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridineIC502900.0 [1]
3-(3-Chloro-4-fluoro-phenyl)-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridineIC507300.0 [1]
3-(2,4-Dichloro-phenyl)-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridineIC50890.0 [1]
3-(3,5-Bis-trifluoromethyl-phenyl)-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridineIC502350.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-p-tolyl-pyridineIC50800.0 [1]
3-[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridin-3-yl]-phenylamineIC506900.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-(4-trifluoromethyl-phenyl)-pyridineIC505710.0 [1]
2-[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridin-3-yl]-benzaldehydeIC506310.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-o-tolyl-pyridineIC501250.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-p-tolylethynyl-pyridineIC501500.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-((E)-2-pyridin-4-yl-vinyl)-pyridineIC507600.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-naphthalen-2-yl-pyridineIC503400.0 [1]
1-Methyl-2-[5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridin-3-yl]-1H-indoleIC506100.0 [1]
3-[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridin-3-yl]-quinolineIC505100.0 [1]
3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-(3-nitro-phenyl)-pyridineIC502330.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Nicotinic acetylcholine receptor alpha3/betaX Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/nicotinic-acetylcholine-receptor-alpha3-betax-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Nicotinic acetylcholine receptor alpha3/betaX Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nicotinic-acetylcholine-receptor-alpha3-betax-inhibitors-ic50-ki.
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