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NF-kappaB inhibitor alpha Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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(1R,2S,5R,8S,9R,17R,18R,21S,24R,26S,27S)-5-Hydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacosa-11,14-diene-4,10,22,29-tetroneIC5037500.0 [1]
5,6-Epxoyphysalin BIC5027100.0 [1]
Physalin AIC5050000.0 [1]
Withanolide EIC5018000.0 [1]
(2R)-2-[(1S)-1-[(8R,9S,10R,13S,14R,17S)-14,17-Dihydroxy-10,13-dimethyl-1-oxo-4,7,8,9,11,12,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-1-hydroxyethyl]-4,5-dimethyl-2,3-dihydropyran-6-oneIC5050000.0 [1]
(1S,2S,3R,5R,6S,7R,14R,15S,18R,21S,22R,25S)-5,7,18-Trihydroxy-1,14,21,25-tetramethyl-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,11-diene-13,19,24,27-tetroneIC5050000.0 [1]
(2R)-2-[(1R)-1-Hydroxy-1-[(8R,9S,10R,13R,14R,17S)-14-hydroxy-10,13-dimethyl-1-oxo-7,8,9,11,12,15,16,17-octahydro-4H-cyclopenta[a]phenanthren-17-yl]ethyl]-4,5-dimethyl-2,3-dihydropyran-6-oneIC5050000.0 [1]
Physalin JIC5050000.0 [1]
(2R)-2-[(1R)-1-Hydroxy-1-[(8R,9S,10R,13R,14R)-14-hydroxy-10,13-dimethyl-1-oxo-7,8,9,11,12,15-hexahydro-4H-cyclopenta[a]phenanthren-17-yl]ethyl]-4,5-dimethyl-2,3-dihydropyran-6-oneIC5050000.0 [1]
(3R,4S)-4-[(2R,3S)-3-[(8R,9S,10R,13S,14R,17S)-14,17-Dihydroxy-10,13-dimethyl-1-oxo-4,7,8,9,11,12,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2,3-dihydroxybutyl]-3-methyloxolan-2-oneIC5050000.0 [1]
(3R,4S)-4-[(2R,3S)-3-[(8R,9S,10R,13S,14R,17R)-14,17-Dihydroxy-10,13-dimethyl-1-oxo-4,7,8,9,11,12,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2,3-dihydroxybutyl]-3-methyloxolan-2-oneIC5050000.0 [1]
25-Hydroxy physalin JIC5050000.0 [1]
(1S,2S,3R,5R,6R,14R,15S,18R,21S,22R)-5,18-Dihydroxy-1,14,21-trimethyl-25-methylidene-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,11-diene-13,19,24,27-tetroneIC5026200.0 [1]
(1R,2S,5S,8S,9R,16R,17S,18R,21S,24R,26S,27S)-5,16-Dihydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacosa-11,14-diene-4,10,22,29-tetroneIC5050000.0 [1]
25-Hydroxy physalin FIC5030100.0 [1]
(1S,2S,3R,5R,6R,14R,15S,18R,21S,22R,25S)-5,18,25-Trihydroxy-1,14,21,25-tetramethyl-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,11-diene-13,19,24,27-tetroneIC5050000.0 [1]
Items per page: 1 - 10 of 16
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References

This online tool may be cited as follows

MLA

"Quest Database™ NF-kappaB inhibitor alpha Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/nf-kappab-inhibitor-alpha-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ NF-kappaB inhibitor alpha Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nf-kappab-inhibitor-alpha-inhibitors-ic50-ki.
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