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Neutral cholesterol ester hydrolase 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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CID 10427006IC50100000.0 [1]
1-(Oxazol-2-yl)-7-phenylheptan-1-oneIC5019000.0 [1], 20000.0 [2]
2-(7-Phenylheptanoyl)oxazole-5-carbonitrileIC50100000.0 [1]
2-(7-Phenylheptanoyl)oxazole-5-carboxylic acidIC50100000.0 [1]
6-[2-(7-Phenylheptanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acidIC50100000.0 [1]
(2-Fluorophenyl) N-[2-[[(1R,2S)-2-(butoxymethyl)cyclohexyl]methoxy]ethyl]carbamateIC50100.0 [1], 150.0 [2], 5400.0 [3]
7-Phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-1-oneIC50100000.0 [1]
Methyl 2-(7-phenylheptanoyl)oxazole-5-carboxylateIC50100000.0 [1]
(1-Bromonaphthalen-2-yl) N-butylcarbamateIC502200.0 [1], 37000.0 [2]
(1-Bromonaphthalen-2-yl) N-benzylcarbamateIC50710.0 [1], 27000.0 [2]
(1-Bromonaphthalen-2-yl) azetidine-1-carboxylateIC50330.0 [1], 2000.0 [2]
(1-Bromonaphthalen-2-yl) N-propan-2-ylcarbamateIC501500.0 [1], 28000.0 [2]
1-Bromo-2-naphthyl piperidinecarboxylateIC501100.0 [1], 42000.0 [2]
1-Bromonaphthalen-2-yl N,N-dimethylcarbamateIC501200.0 [1], 1700.0 [2]
OrlistatIC50100000.0 [1]
1,6-Bis(cyclohexyloximinocarbonyl)hexaneIC5010000.0 [1]
7-Phenyl-1-(5-phenyloxazol-2-yl)heptan-1-oneIC50100000.0 [1]
7-Phenyl-1-[5-(Pyridin-2-Yl)-1,3,4-Oxadiazol-2-Yl]heptan-1-OneIC5090000.0 [1]
1-(5-(Furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-oneIC50100000.0 [1]
1-Chloro-2-naphthyl dimethylcarbamateIC501100.0 [1]
7-Phenyl-1-(5-phenyl-1,3,4-oxadiazol-2-yl)heptan-1-oneIC50100000.0 [1]
7-Phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-oneIC50100000.0 [1]
3-(4-Phenylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]propan-1-oneIC50100000.0 [1]
1-[5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl]-7-phenylheptan-1-oneIC50100000.0 [1]
1-(5-Bromooxazol-2-yl)-7-phenylheptan-1-oneIC5013000.0 [1]
Methyl 6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinateIC50240000.0 [1]
3-(4-(Phenoxymethyl)phenyl)-1-(5-(pyridin-2-yl)oxazol-2-yl)propan-1-oneIC50100000.0 [1]
2-(3-(Biphenyl-4-yl)propanoyl)oxazole-5-carbonitrileIC5064000.0 [1]
7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-heptan-1-oneIC50100000.0 [1]
7-Phenyl-1-(2H-tetrazol-5-yl)-heptan-1-oneIC5060000.0 [1]
2-(7-Phenylheptanoyl)oxazole-5-carboxamideIC50100000.0 [1]
3-(2-(7-Phenylheptanoyl)oxazol-5-yl)benzamideIC50100000.0 [1]
1-(5-(4-Methoxypyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-oneIC50100000.0 [1]
6-(2-(7-Phenylheptanoyl)oxazol-5-yl)nicotinic acidIC50100000.0 [1]
3-(2-(7-Phenylheptanoyl)oxazol-5-yl)benzoic acidIC50100000.0 [1]
3-(2-(7-Phenylheptanoyl)oxazol-5-yl)benzenesulfonamideIC50100000.0 [1]
1-(5-(4-Methylpyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-oneIC50100000.0 [1]
1-Oxo-1-[5-(2-pyridyl)oxazol-2-yl]-3-(4-phenoxyphenyl)propaneIC50100000.0 [1]
6-[2-(3-Biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acidIC50100000.0 [1]
7-Phenyl-1-[5-[6-(2H-tetrazol-5-yl)pyridin-2-yl]-1,3-oxazol-2-yl]heptan-1-oneIC50100000.0 [1]
Methyl 3-(7-Phenylheptanoyl)-1,2,4-oxadiazole-5-carboxylateIC50100000.0 [1]
7-Phenyl-1-(5-(pyridin-2-yl)-thiazol-2-yl)-heptan-1-oneIC50100000.0 [1]
Methyl 5-(7-Phenylheptanoyl)-1,3,4-thiadiazole-2-carboxylateIC50100000.0 [1]
1-(1,3,4-Oxadiazol-2-yl)-7-phenylheptan-1-oneIC50100000.0 [1]
6-(5-(7-Phenylheptanoyl)-1,3,4-oxadiazol-2-yl)picolinic acidIC50100000.0 [1]
1-(1,2,4-Oxadiazol-5-yl)-7-phenylheptan-1-oneIC5025000.0 [1]
7-Phenyl-1-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)heptan-1-oneIC5030000.0 [1]
Methyl 6-(5-(7-Phenylheptanoyl)-1,2,4-oxadiazol-3-yl)-picolinateIC5040000.0 [1]
6-(5-(7-Phenylheptanoyl)-1,2,4-oxadiazol-3-yl)-picolinic AcidIC50100000.0 [1]
7-Phenyl-1-(5-(pyridin-2-yl)-1,2,4-oxadiazol-3-yl)-heptan-1-oneIC50100000.0 [1]
7-Phenyl-1-(1,3,4-thiadiazol-2-yl)-heptan-1-oneIC50100000.0 [1]
7-Phenyl-1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)-heptan-1-oneIC50100000.0 [1]
7-Phenyl-1-(pyridazin-3-yl)-heptan-1-oneIC50100000.0 [1]
7-Phenyl-1-(6-(pyridin-2-yl)-pyridazin-3-yl)-heptan-1-oneIC50100000.0 [1]
2-(7-Phenylheptanoyl)oxazole-4-carbonitrileIC5030000.0 [1]
7-Phenyl-1-(4-(pyridin-2-yl)oxazol-2-yl)heptan-1-oneIC50100000.0 [1]
7-Phenyl-1-(4-(pyridin-4-yl)oxazol-2-yl)heptan-1-oneIC50100000.0 [1]
7-Phenyl-1-(4-(trifluoromethyl)oxazol-2-yl)heptan-1-oneIC5010000.0 [1]
1,6-Dibromonaphthalen-2-yl N,N-dimethylcarbamateIC5050.0 [1]
2-(2-(7-Phenylheptanoyl)oxazol-5-yl)isonicotinonitrileIC50100000.0 [1]
1-(5-(4-Nitropyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-oneIC50100000.0 [1]
1-(5-(4-Fluoropyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-oneIC50100000.0 [1]
Methyl 2-(2-(7-phenylheptanoyl)oxazol-5-yl)isonicotinateIC50100000.0 [1]
6-(2-(7-Phenylheptanoyl)oxazol-5-yl)pyrimidine-2,4(1H,3H)-dioneIC50100000.0 [1]
7-Phenyl-1-(5-(4-(trifluoromethyl)pyridin-2-yl)oxazol-2-yl)heptan-1-oneIC50100000.0 [1]
1-(5-(4-Aminopyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-oneIC50100000.0 [1]
5-(2-(7-Phenylheptanoyl)oxazol-5-yl)furan-2-carboxylic acidIC50100000.0 [1]
7-Phenyl-1-(5-(piperidine-1-carbonyl)oxazol-2-yl)heptan-1-oneIC50100000.0 [1]
5-(2-(7-Phenylheptanoyl)oxazol-5-yl)pyrimidine-2,4(1H,3H)-dioneIC50100000.0 [1]
2-Naphthyl dimethylcarbamateIC50100000.0 [1]
2-Bromophenyl DimethylcarbamateIC50100000.0 [1]
1-(5-(2,6-Dimethoxypyrimidin-4-yl)oxazol-2-yl)-7-phenylheptan-1-oneIC50100000.0 [1]
1-(5-(2,4-Dimethoxypyrimidin-5-yl)oxazol-2-yl)-7-phenylheptan-1-oneIC50100000.0 [1]
3-(4-Phenylphenyl)-1-[5-[6-(2H-tetrazol-5-yl)pyridin-2-yl]-1,3-oxazol-2-yl]propan-1-oneIC50100000.0 [1]
1-(1,3-Oxazol-2-yl)-3-(4-phenoxyphenyl)propan-1-oneIC50100000.0 [1]
2-[3-(4-Phenoxyphenyl)propanoyl]-1,3-oxazole-5-carbonitrileIC5020000.0 [1]
6-(2-(3-(4-Phenoxyphenyl)propanoyl)oxazol-5-yl)pyridine-2-carboxylic acidIC50100000.0 [1]
1-(1,3-Oxazol-2-yl)-3-[4-(phenoxymethyl)phenyl]propan-1-oneIC50100000.0 [1]
2-[3-[4-(Phenoxymethyl)phenyl]propanoyl]-1,3-oxazole-5-carbonitrileIC5019000.0 [1]
2-[3-(4-Phenylphenyl)propanoyl]-1,3-oxazole-5-carboxylic acidIC50100000.0 [1]
1-(5-(6-(1H-Tetrazol-5-yl)pyridin-2-yl)oxazol-2-yl)-3-(4-(phenoxymethyl)phenyl)propan-1-oneIC50100000.0 [1]
2-[3-(4-Phenoxyphenyl)propanoyl]-1,3-oxazole-5-carboxylic acidIC50100000.0 [1]
2-[3-[4-(Phenoxymethyl)phenyl]propanoyl]-1,3-oxazole-5-carboxylic acidIC50100000.0 [1]
6-(2-(3-(4-(Phenoxymethyl)phenyl)propanoyl)oxazol-5-yl)pyridine-2-carboxylic acidIC50100000.0 [1]
1-(1,3-Oxazol-2-yl)-3-(4-phenylphenyl)propan-1-oneIC50100000.0 [1]
6-(6-(7-Phenylheptanoyl)-pyridazin-3-yl)-picolinic AcidIC50100000.0 [1]
Methyl 5-(7-Phenylheptanoyl)-1,3,4-oxadiazole-2-carboxylateIC50100000.0 [1]
6-(6-(7-Phenylheptanoyl)pyridazin-3-yl)picolinonitrileIC50100000.0 [1]
6-(3-(7-Phenylheptanoyl)-1,2,4-oxadiazol-5-yl)-picolinic AcidIC50100000.0 [1]
6-(2-(7-Phenylheptanoyl)thiazol-5-yl)-picolinic AcidIC50100000.0 [1]
Methyl 6-(5-(7-Phenylheptanoyl)-1,3,4-thiadiazol-2-yl)-picolinateIC50100000.0 [1]
Methyl 6-(6-(7-Phenylheptanoyl)-pyridazin-3-yl)-picolinateIC50100000.0 [1]
Methyl 6-(5-(7-Phenylheptanoyl)-1,3,4-oxadiazol-2-yl)-picolinateIC50100000.0 [1]
1-(1,2,4-Oxadiazol-3-yl)-7-phenylheptan-1-oneIC50100000.0 [1]
Methyl 6-(3-(7-Phenylheptanoyl)-1,2,4-oxadiazol-5-yl)-picolinateIC50100000.0 [1]
7-Phenyl-1-(thiazol-2-yl)-heptan-1-oneIC50100000.0 [1]
Methyl 6-(2-(7-Phenylheptanoyl)-thiazol-5-yl)-picolinateIC50100000.0 [1]
6-(5-(7-Phenylheptanoyl)-1,3,4-thiadiazol-2-yl)-picolinic AcidIC50100000.0 [1]
2-(7-Phenylheptanoyl)oxazole-4-carboxylic acidIC50100000.0 [1]
(1-Bromo-6-propylnaphthalen-2-yl) N,N-dimethylcarbamateIC50130.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Neutral cholesterol ester hydrolase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/neutral-cholesterol-ester-hydrolase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Neutral cholesterol ester hydrolase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/neutral-cholesterol-ester-hydrolase-1-inhibitors-ic50-ki.
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