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Neuropeptides B/W receptor type 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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5-Chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)-3-pyridazinoneIC50270.0 [1]
[4-(5-Chloropyridin-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[[(1R)-1-(4-methoxyphenyl)ethyl]amino]-2-thiophen-3-ylcyclohexyl]methanoneIC50324.0 [1], 1925.0 [2]
[4-(1H-Benzimidazol-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[2-(4-methoxyphenyl)propan-2-ylamino]-2-thiophen-3-ylcyclohexyl]methanoneIC5035.0 [1], 39.0 [2]
[4-(1,3-Benzoxazol-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[[1-(4-methoxyphenyl)cyclobutyl]amino]-2-thiophen-3-ylcyclohexyl]methanoneIC504.2 [1], 40.0 [2]
[4-(1H-Benzimidazol-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[[1-(4-methoxyphenyl)cyclobutyl]amino]-2-thiophen-3-ylcyclohexyl]methanoneIC505.9 [1], 11.0 [2]
[(1S,2S,4R)-4-[[1-(4-Methoxyphenyl)cyclobutyl]amino]-2-thiophen-3-ylcyclohexyl]-[4-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperazin-1-yl]methanoneIC5095.0 [1], 342.0 [2]
[(1S,2S,4R)-4-[[1-(4-Methoxyphenyl)cyclobutyl]amino]-2-thiophen-3-ylcyclohexyl]-[4-(5-methyl-1,3-benzoxazol-2-yl)piperazin-1-yl]methanoneIC506.0 [1], 70.0 [2]
[4-(1,3-Benzoxazol-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[2-(4-methoxyphenyl)propan-2-ylamino]-2-thiophen-3-ylcyclohexyl]methanoneIC5021.0 [1], 110.0 [2]
[4-(5-Bromo-1,3,4-thiadiazol-2-yl)piperazin-1-yl]-[(1S,2S,4R)-4-[[1-(4-methoxyphenyl)cyclobutyl]amino]-2-thiophen-3-ylcyclohexyl]methanoneIC5018.0 [1], 197.0 [2]
5-Chloro-4-(4-methoxyphenoxy)-2-(4-methylphenyl)-3(2H)-pyridazinoneIC502200.0 [1]
5-Chloro-2-(4-fluorophenyl)-4-(4-methoxyphenoxy)-3(2H)-pyridazinoneIC503600.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-phenyl-3(2H)-pyridazinoneIC5013000.0 [1]
5-Chloro-2-(9H-fluoren-9-yl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC50120.0 [1]
5-Chloro-2-(4-chlorophenyl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC501770.0 [1]
5-Chloro-2-(2,3-dimethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC501300.0 [1]
2-(4-Bromophenyl)-5-chloro-4-(4-methoxyphenoxy)-3(2H)-pyridazinoneIC50690.0 [1]
5-Bromo-4-(4-methoxyphenoxy)-2-(4-methylphenyl)-3(2H)-pyridazinoneIC50780.0 [1]
5-Chloro-4-phenoxy-2-(p-tolyl)pyridazin-3-oneIC5020000.0 [1]
5-Chloro-4-(3,4-dimethoxyphenoxy)-2-(p-tolyl)pyridazin-3-oneIC5020000.0 [1]
5-Bromo-4-(4-ethoxyphenoxy)-2-(4-propan-2-ylphenyl)-3-pyridazinoneIC50720.0 [1]
CID 46172918IC50650.0 [1]
5-Chloro-4-(4-ethylphenoxy)-2-(4-methylphenyl)-3-pyridazinoneIC50680.0 [1]
2-(4-Tert-butylphenyl)-5-chloranyl-4-(4-methoxyphenoxy)pyridazin-3-oneIC50680.0 [1]
5-Chloro-2-m-cumenyl-4-(4-methoxyphenoxy)pyridazin-3-oneIC50280.0 [1]
5-Chloro-4-(4-ethoxyphenoxy)-2-(4-methylphenyl)-3-pyridazinoneIC50990.0 [1]
5-Chloro-4-(4-methylolphenoxy)-2-(p-tolyl)pyridazin-3-oneIC502300.0 [1]
5-Bromanyl-4-(4-methoxyphenoxy)-2-(4-propan-2-ylphenyl)pyridazin-3-oneIC50720.0 [1]
5-Chloro-2-(p-tolyl)-4-[4-(trifluoromethoxy)phenoxy]pyridazin-3-oneIC502200.0 [1]
5-Chloro-2-(4-ethylphenyl)-4-(4-methoxyphenoxy)-3-pyridazinoneIC50580.0 [1]
5-Chloro-2-(4-cyclopropylphenyl)-4-(4-methoxyphenoxy)-3-pyridazinoneIC501100.0 [1]
5-Cyclopropyl-4-(4-methoxyphenoxy)-2-(p-tolyl)pyridazin-3-oneIC506200.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(4-sec-butylphenyl)pyridazin-3-oneIC50650.0 [1]
5-Chloro-2-(p-tolyl)-4-[4-(trifluoromethyl)phenoxy]pyridazin-3-oneIC50880.0 [1]
5-Chloranyl-2-(2,5-dimethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC501400.0 [1]
Ethyl 4-[4-chloro-5-(4-methoxyphenoxy)-6-oxopyridazin-1-yl]benzoateIC501200.0 [1]
5-Ethenyl-4-(4-methoxyphenoxy)-2-(4-propan-2-ylphenyl)-3-pyridazinoneIC502400.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(1-naphthalenyl)-3-pyridazinoneIC50360.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-tetralin-5-yl-pyridazin-3-oneIC50650.0 [1]
4-(4-Methoxyphenoxy)-5-methyl-2-(4-propan-2-ylphenyl)-3-pyridazinoneIC507500.0 [1]
N-[5-(4-Methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)pyridazin-4-yl]acetamideIC5020000.0 [1]
5-(4-Methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)-4-pyridazinecarbonitrileIC504200.0 [1]
5-(Hydroxymethyl)-4-(4-methoxyphenoxy)-2-(4-propan-2-ylphenyl)-3-pyridazinoneIC505600.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(m-tolyl)pyridazin-3-oneIC50570.0 [1]
5-(4-Methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)pyridazine-4-carboxylic acidIC5020000.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(3-methyl-4-propan-2-ylphenyl)-3-pyridazinoneIC50300.0 [1]
5-(4-Methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)-4-pyridazinecarboxaldehydeIC506200.0 [1]
5-Chloranyl-2-(4-propan-2-ylphenyl)-4-[4-(trifluoromethyloxy)phenoxy]pyridazin-3-oneIC5012200.0 [1]
Methyl 5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)pyridazine-4-carboxylateIC502700.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(4-methylbenzyl)pyridazin-3-oneIC501700.0 [1]
5-Amino-4-(4-methoxyphenoxy)-2-(4-propan-2-ylphenyl)pyridazin-3-oneIC5020000.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-tetralin-6-yl-pyridazin-3-oneIC50650.0 [1]
5-Ethyl-4-(4-methoxyphenoxy)-2-(4-propan-2-ylphenyl)-3-pyridazinoneIC5010700.0 [1]
5-Chloranyl-2-(3-chlorophenyl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC50690.0 [1]
2-(3-Bromophenyl)-5-chloro-4-(4-methoxyphenoxy)pyridazin-3-oneIC50710.0 [1]
4-(4-Methoxyphenoxy)-5-phenyl-2-(p-tolyl)pyridazin-3-oneIC5020000.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(4-propan-2-ylphenyl)-3-pyridazinoneIC50270.0 [1]
5-(2-Furyl)-4-(4-methoxyphenoxy)-2-(p-tolyl)pyridazin-3-oneIC5014280.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(3-methoxyphenyl)-3-pyridazinoneIC50410.0 [1]
5-Chloro-2-(3,5-dimethylphenyl)-4-[4-(hydroxymethyl)phenoxy]pyridazin-3-oneIC50440.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[naphthalen-1-yl(phenyl)methyl]pyridazin-3-oneIC5018000.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[(4-phenylphenyl)methyl]pyridazin-3-oneIC509400.0 [1]
5-Chloro-2-(cyclopentylmethyl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC503700.0 [1]
5-Chloro-4-(4-hydroxyphenoxy)-2-(4-methylphenyl)pyridazin-3-oneIC501300.0 [1]
[2-[4-Chloro-5-(4-methoxyphenoxy)-6-oxopyridazin-1-yl]-2-naphthalen-1-ylethyl] acetateIC5011600.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(naphthalen-2-ylmethyl)pyridazin-3-oneIC501500.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[4-(trifluoromethyl)phenyl]pyridazin-3-oneIC50750.0 [1]
5-Chloro-6-methoxy-4-(4-methoxyphenoxy)-2-(3-methylphenyl)pyridazin-3-oneIC502100.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(2-naphthalen-1-ylethyl)pyridazin-3-oneIC504200.0 [1]
5-Chloro-4-(4-ethoxyphenoxy)-2-(naphthalen-1-ylmethyl)pyridazin-3-oneIC50100.0 [1]
5-Chloro-2-(2-hydroxy-1-naphthalen-1-ylethyl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC502500.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[[2-(trifluoromethyl)phenyl]methyl]pyridazin-3-oneIC50370.0 [1]
5-Chloro-4-[4-(hydroxymethyl)phenoxy]-2-(naphthalen-1-ylmethyl)pyridazin-3-oneIC504400.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[(3-methylphenyl)methyl]pyridazin-3-oneIC501400.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[(4-methylnaphthalen-1-yl)methyl]pyridazin-3-oneIC50370.0 [1]
5-Chloro-2-(3,4-dimethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC50590.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[(4-propan-2-ylphenyl)methyl]pyridazin-3-oneIC5010000.0 [1]
5-Chloro-2-(3-chlorobenzo[b][1,4]benzoxazepin-6-yl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC50370.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(4-propan-2-yloxyphenyl)pyridazin-3-oneIC50770.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(naphthalen-1-ylmethyl)pyridazin-3-oneIC50140.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(4-phenylphenyl)pyridazin-3-oneIC501710.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-naphthalen-2-ylpyridazin-3-oneIC50160.0 [1]
2-[(4-Bromonaphthalen-1-yl)methyl]-5-chloro-4-(4-methoxyphenoxy)pyridazin-3-oneIC502000.0 [1]
5-Chloro-2-[(3,4-dimethylphenyl)methyl]-4-(4-methoxyphenoxy)pyridazin-3-oneIC50610.0 [1]
5-Chloro-2-[(3,5-dimethylphenyl)methyl]-4-(4-methoxyphenoxy)pyridazin-3-oneIC50410.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(4-pentylphenyl)pyridazin-3-oneIC502570.0 [1]
2-(Anthracen-9-ylmethyl)-5-chloro-4-(4-methoxyphenoxy)pyridazin-3-oneIC50320.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[(4-methoxyphenyl)methyl]pyridazin-3-oneIC503800.0 [1]
5-Chloro-2-[(4-chlorophenyl)methyl]-4-(4-methoxyphenoxy)pyridazin-3-oneIC50590.0 [1]
5-Chloro-2-(3,5-dimethylphenyl)-4-(4-ethoxyphenoxy)pyridazin-3-oneIC50210.0 [1]
5-Chloro-2-[(4-fluoronaphthalen-1-yl)methyl]-4-(4-methoxyphenoxy)pyridazin-3-oneIC50360.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[[3-(trifluoromethyl)phenyl]methyl]pyridazin-3-oneIC501800.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[(2-methylphenyl)methyl]pyridazin-3-oneIC50370.0 [1]
5-Chloro-2-[(2-methoxynaphthalen-1-yl)methyl]-4-(4-methoxyphenoxy)pyridazin-3-oneIC50350.0 [1]
5-Chloro-4-(4-hydroxyphenoxy)-2-(4-propan-2-ylphenyl)pyridazin-3-oneIC504800.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(2-oxo-1,2-diphenylethyl)pyridazin-3-oneIC50580.0 [1]
5-Chloro-2-(3-ethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC50230.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-[[4-(trifluoromethyl)phenyl]methyl]pyridazin-3-oneIC501000.0 [1]
5-Chloro-2-(2,4-dimethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-oneIC50980.0 [1]
Ethyl 2-[4-chloro-5-(4-methoxyphenoxy)-6-oxopyridazin-1-yl]-2-naphthalen-1-ylacetateIC50450.0 [1]
5-Chloro-4-(4-methoxyphenoxy)-2-(1-naphthalen-1-ylethyl)pyridazin-3-oneIC501900.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Neuropeptides B/W receptor type 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/neuropeptides-b-w-receptor-type-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Neuropeptides B/W receptor type 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/neuropeptides-b-w-receptor-type-1-inhibitors-ic50-ki.
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