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Neuropeptide Y receptor type 2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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Unii-OW44B6FA0YIC5063.1 [1]
Human Neuropeptide YIC500.03 [1], 0.09 [2], 0.19 [3], 0.5 [4]
Human Neuropeptide YKi0.8 [1]
N-(2-Benzylsulfanylphenyl)-N-[3-(dimethylamino)propyl]-1-benzothiophene-2-carboxamideIC50450.0 [1], 1000.0 [2]
N-(4-Ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamideIC50190.0 [1], 200.0 [2]
CID 16132350IC500.32 [1]
CID 16132350Ki0.08 [1], 0.3 [2]
Neuropeptide Y (24-36) amide, N-acetyl-(leu(28,31))-IC503.9 [1]
Neuropeptide Y (24-36) amide, N-acetyl-(leu(28,31))-Ki5.0 [1]
CID 16200926IC500.57 [1]
CID 16200926Ki0.4 [1]
(2R)-5-(Diaminomethylideneamino)-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[[2-[1-[2-oxo-2-[4-(6-oxo-5,11-dihydrobenzo[c][1]benzazepin-11-yl)piperazin-1-yl]ethyl]cyclopentyl]acetyl]amino]pentanamideIC503.3 [1]
(2R)-5-(Diaminomethylideneamino)-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[[2-[1-[2-oxo-2-[4-(6-oxo-5,11-dihydrobenzo[c][1]benzazepin-11-yl)piperazin-1-yl]ethyl]cyclopentyl]acetyl]amino]pentanamideKi2.6 [1]
(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]pentanediamideIC50132.0 [1]
(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]pentanediamideKi7.1 [1], 1506.0 [2]
Jnj-31020028IC506.0 [1]
3-[(2,5-Dimethylphenyl)sulfamoyl]-4-methyl-N-(2-phenylphenyl)benzamideIC50440.0 [1]
2-(2-Methoxyphenyl)-N-[4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamideIC501200.0 [1]
3,5-Dimethyl-4-[(4-methylphenyl)sulfonyl-phenylmethyl]isoxazoleIC504400.0 [1]
N-{3-Chloro-4-[4-(phenylcarbonyl)piperazin-1-yl]phenyl}-2,2-dimethylpropanamideKi501.19 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-[1-(2-cyclohexylethyl)piperidin-4-yl]-3-phenylprop-2-enamideIC50600.0 [1]
(E)-N-(1-Benzyl-piperidin-4-yl)-N-(1-methanesulfonyl-2,3-dihydro-1H-indol-6-yl)-3-phenyl-acrylamideIC5015000.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-[1-(2-cyclopentylethyl)piperidin-4-yl]-3-phenylprop-2-enamideIC50800.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-(1-benzylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]prop-2-enamideIC508900.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-(1-benzylpiperidin-4-yl)-3-(3,5-difluorophenyl)prop-2-enamideIC502500.0 [1]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-(3-nitro-phenyl)-acrylamideIC501900.0 [1]
(E)-N-(1-Benzyl-piperidin-4-yl)-N-(1-formyl-2,3-dihydro-1H-indol-6-yl)-3-phenyl-acrylamideIC503500.0 [1]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-pyridin-4-yl-acrylamideIC5012000.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-(1-benzylpiperidin-4-yl)-3-(3,5-dimethylphenyl)prop-2-enamideIC503900.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-(1-benzylpiperidin-4-yl)-3-(3,5-dichlorophenyl)prop-2-enamideIC5030000.0 [1]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-phenethyl-piperidin-4-yl)-3-phenyl-acrylamideIC5026000.0 [1]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-(3-cyano-phenyl)-acrylamideIC501000.0 [1]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-thiophen-3-yl-acrylamideIC503200.0 [1]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-cyclohexylmethyl-piperidin-4-yl)-3-phenyl-acrylamideIC501100.0 [1]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzoyl-piperidin-4-yl)-3-phenyl-acrylamideIC5029000.0 [1]
(E)-N-(1-Benzyl-piperidin-4-yl)-N-(1-methyl-2,3-dihydro-1H-indol-6-yl)-3-phenyl-acrylamideIC505300.0 [1]
(2E,4E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-(1-benzylpiperidin-4-yl)-5-phenylpenta-2,4-dienamideIC502800.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-(1-benzylpiperidin-4-yl)-3-[4-(trifluoromethyl)phenyl]prop-2-enamideIC502800.0 [1]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-(3-bromo-phenyl)-acrylamideIC503300.0 [1]
1-{6-[(1-Benzyl-piperidin-4-yl)-((E)-3-phenyl-allyl)-amino]-2,3-dihydro-indol-1-yl}-ethanoneIC5030000.0 [1]
(E)-N-(1-Benzylpiperidin-4-yl)-3-phenyl-N-[1-(2,2,2-trifluoroacetyl)-2,3-dihydroindol-6-yl]prop-2-enamideIC5030000.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-(1-benzylpiperidin-4-yl)-3-(3-fluorophenyl)prop-2-enamideIC503600.0 [1]
Ethyl 2-[6-[(1-benzylpiperidin-4-yl)-[(E)-3-phenylprop-2-enoyl]amino]-2,3-dihydroindol-1-yl]-2-oxoacetateIC504800.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-(1-benzylpiperidin-4-yl)-2-phenylethenesulfonamideIC5030000.0 [1]
(E)-N-(1-Acetyl-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-phenyl-acrylamideIC5030000.0 [1]
(E)-N-(1-Acetyl-1,2,3,4-tetrahydro-quinolin-7-yl)-N-(1-benzyl-piperidin-4-yl)-3-phenyl-acrylamideIC5010000.0 [1]
(E)-N-(1-Benzyl-piperidin-4-yl)-N-(2,3-dihydro-1H-indol-6-yl)-3-phenyl-acrylamideIC5022000.0 [1]
(E)-N-(1-Benzyl-piperidin-4-yl)-N-(2-oxo-2,3-dihydro-1H-indol-6-yl)-3-phenyl-acrylamideIC5030000.0 [1]
N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-phenyl-propionamideIC5018000.0 [1]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-pyridin-3-yl-acrylamideIC5030000.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-(1-benzylpiperidin-4-yl)-3-(3-chlorophenyl)prop-2-enamideIC503000.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-3-phenyl-N-[1-(3-phenylpropyl)piperidin-4-yl]prop-2-enamideIC502300.0 [1]
(E)-N-(1-Acetyl-2,3-dihydroindol-6-yl)-N-(1-benzylpiperidin-4-yl)-3-(4-chlorophenyl)prop-2-enamideIC503600.0 [1]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-m-tolyl-acrylamideIC501400.0 [1]
(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-1-[(2S)-2-Acetamido-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-pyridin-4-ylpropanoyl]amino]-3-cyclohexylpropanoyl]amino]-2-methylpropanoyl]amino]-4-amino-4-oxobutanoyl]amino]-6-aminohexanoyl]amino]-2-methylpropanoyl]amino]-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-cyclohexyl-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamideIC500.92 [1]
(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-1-[(2S)-2-Acetamido-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-cyclohexylpropanoyl]amino]-3-cyclohexylpropanoyl]amino]-4-amino-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-2-methylpropanoyl]amino]-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-cyclohexyl-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamideIC501.5 [1]
(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-aminobenzoyl)amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]pentanediamideKi4.0 [1]
(E)-N-(2-Benzylsulfanyl-phenyl)-N-(3-dimethylamino-propyl)-3-phenyl-acrylamideIC5010000.0 [1]
N-(2-Benzylsulfanylphenyl)-N-[3-(dimethylamino)propyl]-1-benzofuran-2-carboxamideIC5010000.0 [1]
N-(2-Benzylsulfanylphenyl)-3-chloro-N-[3-(dimethylamino)propyl]-1-benzothiophene-2-carboxamideIC5010000.0 [1]
N-(2-Benzamidophenyl)-N-[3-(dimethylamino)propyl]-1-benzothiophene-2-carboxamideIC5010000.0 [1]
N-(2-Benzylphenyl)-N-[3-(dimethylamino)propyl]-1-benzothiophene-2-carboxamideIC50450.0 [1], 10000.0 [2]
N-[3-(Dimethylamino)propyl]-N-[2-(2-phenylethyl)phenyl]-1-benzothiophene-2-carboxamideIC5010000.0 [1]
(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamidopropanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamideIC501.3 [1]
(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamidopropanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamideKi9.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-5-Amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[6-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]hexanoylamino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acidKi1.0 [1], 12.59 [2]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-Amino-3-[[(2R)-2-amino-3-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-oxopropyl]disulfanyl]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]pentanoyl]amino]-N-[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamideKi3000.0 [1], 10000.0 [2]
(E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-N-(1-benzyl-piperidin-4-yl)-3-phenyl-acrylamideIC504000.0 [1]
N-[3-Chloro-4-[4-(3-methoxypyridine-2-carbonyl)piperazin-1-yl]phenyl]-2-methyl-2-phenylpropanamideKi25.12 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-2-cyclohexylacetyl]amino]-2-cyclohexylacetyl]amino]-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acidIC503.0 [1], 8.0 [2]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]-2-cyclohexylacetyl]amino]-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acidIC505.0 [1], 18.0 [2]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-2-cyclohexylacetyl]amino]-3-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acidIC508.0 [1], 16.0 [2]
Peptide YYKi0.25 [1]
EconazoleKi10988.0 [1]
(2R)-5-(Diaminomethylideneamino)-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamideKi10000.0 [1]
CipargaminIC5010000.0 [1]
N-[[4-[[(4-Aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamideIC501890.0 [1]
N-[[4-(4,5-Dihydro-[1]benzothiepino[5,4-d][1,3]thiazol-2-ylamino)cyclohexyl]methyl]methanesulfonamideIC501000.0 [1]
N-[4-[4-[(1R)-2-(Diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl]-3-fluorophenyl]-2-pyridin-3-ylbenzamideIC509.0 [1]
9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-oneIC5010000.0 [1]
3-Amino-2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-5,6,7,8-tetrahydroquinazolin-4-oneIC501000.0 [1]
4-[Hydroxy(diphenyl)methyl]-N-(4-methoxyphenyl)piperidine-1-carbothioamideIC501100.0 [1]
(2S)-1-[(2S)-4-Amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-4-oxobutanoyl]-N-[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamideKi11.3 [1]
4-(Pyridin-2-yl)-N-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-amineKi31622.78 [1]
3-Oxo-N-(5-phenylpyrazin-2-yl)spiro[2-benzofuran-1,4'-piperidine]-1'-carboxamideIC5010000.0 [1]
CID 44351001Ki0.8 [1]
CID 44351041Ki0.3 [1]
N-[4-[(Dimethylamino)sulfonyl]phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamideIC5019.0 [1]
3-[2-[6-[2-[(2-Methylpropan-2-yl)oxy]ethoxy]pyridin-3-yl]-1H-imidazol-5-yl]benzonitrileIC501000.0 [1]
Ethyl 2-[[N'-[(4R)-4-[(2,2-diphenylacetyl)amino]-5-[(4-hydroxyphenyl)methylamino]-5-oxopentyl]carbamimidoyl]carbamoylamino]acetateKi3000.0 [1]
(2R)-5-[[Amino-(ethylcarbamoylamino)methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamideKi3000.0 [1]
1-(Difluoromethyl)-5-[(4S,5S)-5-(4-fluorophenyl)-5-(6-fluoropyridin-3-yl)-4-methyl-1,4-dihydroimidazol-2-yl]pyridin-2-oneIC5010000.0 [1]
1-Methyl-2-(4-chlorophenoxymethyl)-3-(piperidinomethyl)-1H-indoleKi10000.0 [1]
CID 118718116Ki1000.0 [1]
CID 118718124Ki2.2 [1]
CID 118718320Ki3.6 [1]
(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-6-Amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-3-cyclohexyl-2-[[(2S)-2-[[(2S)-2-[[(2R,4S)-4-hydroxy-1-[(2S)-3-hydroxy-2-(1H-imidazole-5-carbonylamino)propanoyl]pyrrolidine-2-carbonyl]amino]-2-methylbutanoyl]amino]-3-pyridin-4-ylpropanoyl]amino]propanoyl]amino]-4,4-dimethylpentanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]amino]-2-methylpropanoyl]amino]-3-hydroxybutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-3-cyclohexyl-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamideIC500.31 [1]
N-[4-[4-[2-(Diethylamino)-2-oxo-1-phenylethyl]piperidin-1-yl]-3-fluorophenyl]-3,5-dimethyl-1,2-oxazole-4-carboxamideIC5037.0 [1]
2-Diphenylacetylamino-5-guanidino-pentanoic acid 4-hydroxy-benzylamideIC50100000.0 [1]
(2R)-5-[[Amino-(propanoylamino)methylidene]amino]-2-[(2,2-diphenylacetyl)amino]-N-[(4-hydroxyphenyl)methyl]pentanamideKi10000.0 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Neuropeptide Y receptor type 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/neuropeptide-y-receptor-type-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 21). Quest Database™ Neuropeptide Y receptor type 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/neuropeptide-y-receptor-type-2-inhibitors-ic50-ki.
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