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NADPH oxidase 5 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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▼
Standard Type
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▼
Standard Values (in nM)
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▼
(1R,8S,10S)-3,6-Dibromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC5036000.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylpropyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC5018000.0 [1]
(1R,8S,10S)-9-[(3-Fluorophenyl)methyl]-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC5050000.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-(quinolin-4-ylmethyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-3-Bromo-9-(1H-indol-3-ylmethyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-9-(1,3-Benzodioxol-5-ylmethyl)-3-bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
3-[[(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trien-9-yl]methyl]-5-methyl-1,2-oxazoleIC5031000.0 [1]
(1R,8S,10S)-3-Bromo-9-[(3-fluorophenyl)methyl]-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC5079000.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-pentyl-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-9-(1,3-Benzodioxol-5-ylmethyl)-3-(3,4-dichlorophenyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC50100000.0 [1]
(1R,8S,10S)-3-(3,4-Dichlorophenyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-pentyl-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC50100000.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-methylsulfonyl-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-3-Bromo-9-(4-fluorophenyl)sulfonyl-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC5020000.0 [1]
(1R,8S,10S)-11,11-Dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC50100000.0 [1]
(1R,8S,10S)-3-(3,4-Dichlorophenyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC5014000.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-(thiophen-2-ylmethyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-11,11-Dimethyl-10-(2-methylprop-2-enyl)-3-pyridin-3-yl-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC50100000.0 [1]
Tert-butyl 4-(2-chlorophenyl)-3,8-dioxo-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-13-carboxylateKi590.0 [1]
4-(2-Chlorophenyl)-13-[(4-chlorophenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi585.0 [1]
4-(2-Chlorophenyl)-13-(pyridin-3-ylmethyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi1150.0 [1]
12-Benzyl-4-(2-chlorophenyl)-4,5,9,12-tetrazatricyclo[7.4.0.02,6]trideca-1,6-diene-3,8-dione;hydrochlorideKi1425.0 [1]
4-(2-Chlorophenyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi360.0 [1]
4-(2-Chlorophenyl)-13-[(3-chlorophenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi475.0 [1]
4-(2-Chlorophenyl)-12-oxa-4,5,9-triazatricyclo[7.4.0.02,6]trideca-1,6-diene-3,8-dioneKi490.0 [1]
4-(2-Methoxyphenyl)-13-[(3-methoxyphenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi690.0 [1]
13-Benzyl-4-(2-chlorophenyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi414.0 [1]
4-(2-Chlorophenyl)-13-[(2-chlorophenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi615.0 [1]
4-(2-Chlorophenyl)-13-[(4-methoxyphenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi690.0 [1]
13-Benzyl-4-(2-methoxyphenyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi670.0 [1]
4-(2-Chlorophenyl)-13-[(2-methoxyphenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi740.0 [1]
4-(2-Chlorophenyl)-13-[(3-methoxyphenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi730.0 [1]
4-(2-Chlorophenyl)-13-(furan-3-ylmethyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi955.0 [1]
4-(2-Methoxyphenyl)-13-(pyridin-2-ylmethyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi610.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-(thiophen-3-ylmethyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
4-(2-Chlorophenyl)-13-(pyridin-2-ylmethyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dioneKi543.0 [1]
Items per page: 1 - 10 of 36
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References

This online tool may be cited as follows

MLA

"Quest Database™ NADPH oxidase 5 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/nadph-oxidase-5-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ NADPH oxidase 5 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nadph-oxidase-5-inhibitors-ic50-ki.
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