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NAALADase II Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
2-(Phosphonomethyl)pentanedioic acidKi1.4 [1]
(2S,2'S)-2,2'-Carbonylbis(Azanediyl)Dipentanedioic AcidKi8.0 [1]
(2S)-2-[[(1S)-1-Carboxy-2-(4-hydroxyphenyl)ethyl]carbamoylamino]pentanedioic acidKi3.0 [1]
(2S,4S)-2-[[(1S,3S)-1,3-Dicarboxybutyl]carbamoylamino]-4-methylpentanedioic acidKi1109.0 [1]
(2S,4R)-2-[[(1S,3R)-1,3-Dicarboxybutyl]carbamoylamino]-4-methylpentanedioic acidKi1285.0 [1]
(2S)-2-[[(1S)-1-Carboxy-3-(2H-tetrazol-5-yl)propyl]carbamoylamino]-4-(2H-tetrazol-5-yl)butanoic acidKi14.9 [1]
(S)-2-{3-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propyl]-ureido}-pentanedioic acidKi0.9 [1]
(2S,4S)-2-[[(1S)-1,3-Dicarboxypropyl]carbamoylamino]-4-methylpentanedioic acidKi14.4 [1]
(S)-2-[3-((S)-1-Carboxy-2-phenyl-ethyl)-ureido]-pentanedioic acidKi12.0 [1]
(2R,4S)-2-Benzyl-4-[[(1S)-1,3-dicarboxypropyl]carbamoylamino]pentanedioic acidKi95.3 [1]
(S)-2-[3-((S)-1,3-Dicarboxy-1-methyl-propyl)-ureido]-2-methyl-pentanedioic acidKi939.0 [1]
(S)-2-[3-((S)-Carboxy-phenyl-methyl)-ureido]-pentanedioic acidKi2.1 [1]
(2S)-2-[[(1S)-3-Carboxy-1-[1-(2-cyanoethyl)tetrazol-5-yl]propyl]carbamoylamino]pentanedioic acidKi2711.0 [1]
(4S)-4-[[(1S)-3-Carboxy-1-(2H-tetrazol-5-yl)propyl]carbamoylamino]-4-(2H-tetrazol-5-yl)butanoic acidKi4388.0 [1]
(2S)-2-[[(1S)-1-Carboxy-3-[1-(2-cyanoethyl)tetrazol-5-yl]propyl]carbamoylamino]pentanedioic acidKi5.3 [1]
(S)-2-{3-[(S)-Carboxy-(4-hydroxy-phenyl)-methyl]-ureido}-pentanedioic acidKi5.9 [1]
(4S)-4-[[(1S)-3-Carboxy-1-[1-(2-cyanoethyl)tetrazol-5-yl]propyl]carbamoylamino]-4-[1-(2-cyanoethyl)tetrazol-5-yl]butanoic acidKi100000.0 [1]
(2S)-2-[[(1S)-1-Carboxy-3-[1-(2-cyanoethyl)tetrazol-5-yl]propyl]carbamoylamino]-4-[1-(2-cyanoethyl)tetrazol-5-yl]butanoic acidKi4434.0 [1]
(2S)-2-[[(1S)-3-Carboxy-1-(5H-tetrazol-5-yl)propyl]carbamoylamino]pentanedioic acidKi335.0 [1]
(2R,4S)-2-Benzyl-4-[[(1S,3S)-1,3-dicarboxy-4-phenylbutyl]carbamoylamino]pentanedioic acidKi392.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ NAALADase II Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/naaladase-ii-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ NAALADase II Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/naaladase-ii-inhibitors-ic50-ki.
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