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N-type calcium channel alpha-1b/alpha2delta-1/beta-1b Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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1-[4-(Diphenylmethyl)-1-piperazinyl]-3,3-diphenyl-1-propanoneIC50110.0 [1]
N,4-Dibenzhydrylpiperazine-1-carboxamideIC50150.0 [1]
1-(4-Benzhydrylpiperazin-1-yl)-2-(N-phenylanilino)ethanoneIC506610.0 [1]
2-(4-(Diphenylmethyl)piperazinyl)-N,N-diphenylethanamideIC50260.0 [1]
1-[4-[(2-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC5090.0 [1]
1-[4-[(2,6-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50210.0 [1]
1-[4-[(2,4-Dimethylphenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50230.0 [1]
1-[4-[(3-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC5040.0 [1]
3,3-Diphenyl-1-[4-[phenyl-[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]propan-1-oneIC50300.0 [1]
3,3-Diphenyl-1-[4-[phenyl-(3,4,5-trimethoxyphenyl)methyl]piperazin-1-yl]propan-1-oneIC50510.0 [1]
1-[4-[(3,4-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC501000.0 [1]
1-[4-[(4-Fluorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50380.0 [1]
1-{4-[(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-3,3-diphenyl-propan-1-oneIC50110.0 [1]
1-[4-[Bis(4-methoxyphenyl)methyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50240.0 [1]
1-[4-[(2,3-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50220.0 [1]
1-[4-[(4-Methylphenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50310.0 [1]
1-[4-(1-Methyl-piperidin-4-ylmethyl)piperazin-1-yl]-3,3-diphenyl-propan-1-oneIC502400.0 [1]
1-[4-[(3,5-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50170.0 [1]
1-[4-[(4-Methoxyphenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50250.0 [1]
1-[4-[(2,4-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC501000.0 [1]
N-Benzhydryl-4-[(2,3-dichlorophenyl)-phenylmethyl]piperazine-1-carboxamideIC50200.0 [1]
N-Benzhydryl-4-[(4-chlorophenyl)-phenylmethyl]piperazine-1-carboxamideIC50280.0 [1]
1-[4-[(2,4-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-2-(N-phenylanilino)ethanoneIC50460.0 [1]
2-[4-[(2,4-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamideIC50510.0 [1]
2-[4-[(2,4-Dimethylphenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamideIC501250.0 [1]
2-[4-[(4-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamideIC50110.0 [1]
2-[4-[(3-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamideIC50320.0 [1]
2-[4-[(2,3-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamideIC50240.0 [1]
N-Benzhydryl-4-[(2,4-dimethylphenyl)-phenylmethyl]piperazine-1-carboxamideIC502710.0 [1]
1-[4-[(2,3-Dichlorophenyl)-phenylmethyl]piperazin-1-yl]-2-(N-phenylanilino)ethanoneIC50140.0 [1]
1-[4-[(2-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-2-(N-phenylanilino)ethanoneIC50320.0 [1]
2-[4-[(2-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-N,N-diphenylacetamideIC5050.0 [1]
N-Benzhydryl-4-[(2-chlorophenyl)-phenylmethyl]piperazine-1-carboxamideIC50180.0 [1]
1-{4-[(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-2-diphenylaminoethanoneIC50500.0 [1]
1-[4-[(3-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-2-(N-phenylanilino)ethanoneIC50280.0 [1]
N-Benzhydryl-4-[(2,4-dichlorophenyl)-phenylmethyl]piperazine-1-carboxamideIC501480.0 [1]
N-Benzhydryl-4-[(3-chlorophenyl)-phenylmethyl]piperazine-1-carboxamideIC50340.0 [1]
1-[4-[(2,4-Dimethylphenyl)-phenylmethyl]piperazin-1-yl]-2-(N-phenylanilino)ethanoneIC50260.0 [1]
3,3-Diphenyl-1-[4-[phenyl-[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]propan-1-oneIC5070.0 [1]
1-[4-[(R)-(4-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC5050.0 [1]
1-[4-[(S)-(4-Chlorophenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50140.0 [1]
3,3-Diphenyl-1-[4-[phenyl(piperidin-4-yl)methyl]piperazin-1-yl]propan-1-oneIC5060.0 [1]
1-[4-[(1-Methylpiperidin-4-yl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50690.0 [1]
1-[4-[(1-Methylpiperidin-3-yl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50270.0 [1]
1-[4-[(4-Chlorophenyl)-(1-methylpiperidin-4-yl)methyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC5040.0 [1]
1-[4-[(4-Fluorophenyl)-(1-methylpiperidin-4-yl)methyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50100.0 [1]
3,3-Diphenyl-1-[4-(piperidin-4-ylmethyl)piperazin-1-yl]propan-1-oneIC502500.0 [1]
3,3-Diphenyl-1-[4-(piperidin-2-ylmethyl)piperazin-1-yl]propan-1-oneIC502700.0 [1]
1-[4-[(3,5-Dimethoxyphenyl)-phenylmethyl]piperazin-1-yl]-3,3-diphenylpropan-1-oneIC50210.0 [1]
3,3-Diphenyl-1-[4-[phenyl-[3-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]propan-1-oneIC50110.0 [1]
Items per page: 1 - 10 of 50
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References

This online tool may be cited as follows

MLA

"Quest Database™ N-type calcium channel alpha-1b/alpha2delta-1/beta-1b Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/n-type-calcium-channel-alpha-1b-alpha2delta-1-beta-1b-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ N-type calcium channel alpha-1b/alpha2delta-1/beta-1b Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/n-type-calcium-channel-alpha-1b-alpha2delta-1-beta-1b-inhibitors-ic50-ki.
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