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Muscle glycogen phosphorylase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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8,9,10-Trihydroxy-7-hydroxymethyl-2-thioxo-6-oxa-1,3-diaza-spiro[4.5]decan-4-oneKi5100.0 [1], 10900.0 [2]
(5S,7S,8S,9S,10S)-8,9,10-Trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dioneKi26000.0 [1], 105000.0 [2]
CaffeineIC50114000.0 [1]
AlvocidibIC501000.0 [1]
alpha-D-GlucoseKi1700000.0 [1]
Maslinic acidIC5028000.0 [1]
Corosolic acidIC5020000.0 [1]
MaltoheptaoseKi1000000.0 [1]
5-Chloro-1H-indole-2-carboxylic acid [1-(4-fluorobenzyl)-2-(4-hydroxypiperidin-1YL)-2-oxoethyl]amideIC50500.0 [1]
(S)-1-Ethyl-6-methyl-4-phenyl-1,4-dihydro-pyridine-2,3,5-tricarboxylic acid 5-isopropyl esterKi11.0 [1]
5-Chloro-N-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)-1H-indole-2-carboxamideIC5038.0 [1]
4-{2-[(3-Nitrobenzoyl)amino]phenoxy}phthalic acidIC50900.0 [1]
5-Chloro-N-(2-oxo-1,3,4,5-tetrahydro-1-benzazepin-3-yl)-1H-indole-2-carboxamideIC5055.0 [1]
1-Ethyl-2-methyl-4-(2-chlorophenyl)-1,4-dihydro-3,5,6-pyridinetricarboxylic acid 3-isopropyl esterIC50138.0 [1]
5-Chloro-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC5032.0 [1]
5-Methyl-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC5098.0 [1]
5-Fluoro-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC5089.0 [1]
5-Bromo-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC5073.0 [1]
N-(1-Methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC5056.0 [1]
5-Chloro-N-(1-methyl-2-oxo-4,5-dihydro-3H-1-benzazepin-3-yl)-1H-indole-2-carboxamideIC50105.0 [1]
5-Chloro-N-[(3R)-2-oxo-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-1H-indole-2-carboxamideIC5083.0 [1]
5-Chloro-N-[(3S)-2-oxo-3,4-dihydro-1H-quinolin-3-yl]-1H-indole-2-carboxamideIC5039.0 [1]
5-Chloro-N-[(3S)-2-oxo-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-1H-indole-2-carboxamideIC50240.0 [1]
5-Chloro-N-[(3S)-1-methyl-2-oxo-3,4-dihydroquinolin-3-yl]-1H-indole-2-carboxamideIC5057.0 [1]
5-Chloro-N-[(3R)-1-methyl-2-oxo-3,4-dihydroquinolin-3-yl]-1H-indole-2-carboxamideIC5058.0 [1]
N-(1-Methyl-2-oxo-3,4-dihydroquinolin-3-yl)-5-phenyl-1H-indole-2-carboxamideIC5020000.0 [1]
N-(1-Methyl-2-oxo-3,4-dihydroquinolin-3-yl)-5-(trifluoromethyl)-1H-indole-2-carboxamideIC50550.0 [1]
Methyl 2-[(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)carbamoyl]-1H-indole-5-carboxylateIC502700.0 [1]
5-Cyano-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC50110.0 [1]
5-Methoxy-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC501700.0 [1]
5-Ethyl-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC50850.0 [1]
4-Chloro-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC502100.0 [1]
7-Chloro-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC5088.0 [1]
N-(1-Methyl-2-oxo-3,4-dihydroquinolin-3-yl)-6-phenyl-1H-indole-2-carboxamideIC5020000.0 [1]
6-Chloro-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC5069.0 [1]
Methyl 5-chloro-2-[(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)carbamoyl]-1H-indole-4-carboxylateIC5020000.0 [1]
7-Amino-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC506800.0 [1]
5-Chloro-7-fluoro-N-(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)-1H-indole-2-carboxamideIC5055.0 [1]
Methyl 5-chloro-2-[(1-methyl-2-oxo-3,4-dihydroquinolin-3-yl)carbamoyl]-1H-indole-6-carboxylateIC5020000.0 [1]
3,4-Dichloro-N-(2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-benzamideIC502310.0 [1]
3,4-Dichloro-N-(2-oxo-1,3,4,5-tetrahydro-1-benzazepin-3-yl)benzamideIC5021700.0 [1]
N-(1-Methyl-2-oxo-3,4-dihydroquinolin-3-yl)-7-nitro-1H-indole-2-carboxamideIC50120.0 [1]
5-Chloro-1-(beta-D-Glucopyranosyl)pyrimidine-2,4(1h,3h)-DioneKi1020.0 [1]
5-Bromo-1-(beta-D-Glucopyranosyl)pyrimidine-2,4(1h,3h)-DioneKi3270.0 [1]
1-(beta-D-Glucopyranosyl)-5-Iodopyrimidine-2,4(1h,3h)-DioneKi1940.0 [1]
5-Ethynyl-1-(beta-D-Glucopyranosyl)pyrimidine-2,4(1h,3h)-DioneIC50291400.0 [1]
5-Chloro-N-[(3R)-2-oxo-3,4-dihydro-1H-quinolin-3-yl]-1H-indole-2-carboxamideIC5014.0 [1]
4-[2-(3-Acetyl-benzoylamino)-phenoxy]-phthalic acidIC5050000.0 [1]
N-Furan-2-ylmethyl-4-(4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-ylamino)-benzamideIC50120.0 [1]
4-(4-Methyl-3-oxo-3,4-dihydro-pyrido[2,3-b]pyrazin-2-ylamino)-N-thiophen-2-ylmethyl-benzamideIC50190.0 [1]
4-[2-(3-Carboxy-benzoylamino)-phenoxy]-phthalic acidIC50200000.0 [1]
N-Isoxazol-3-yl-4-(4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-ylamino)-benzamideIC50110.0 [1]
4-[(4-Methyl-3-oxoquinoxalin-2-yl)amino]-N-(thiophen-2-ylmethyl)benzamideIC50110.0 [1]
1-Methyl-3-[4-(1H-pyrrol-2-yl)-phenylamino]-1H-quinoxalin-2-oneIC502500.0 [1]
4-(4-Methyl-3-oxo-3,4-dihydro-quinoxalin-2-ylamino)-N-(2H-pyrazol-3-yl)-benzamideIC50200.0 [1]
4-(7-Fluoro-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-ylamino)-N-thiophen-2-ylmethyl-benzamideIC50140.0 [1]
N-[4-[(4-Methyl-3-oxoquinoxalin-2-yl)amino]phenyl]-1,2-oxazole-5-carboxamideIC50710.0 [1]
4-[[4-(2-Morpholin-4-ylethyl)-3-oxoquinoxalin-2-yl]amino]-N-(thiophen-2-ylmethyl)benzamideIC50350.0 [1]
4-(4,6-Dimethyl-3-oxo-3,4-dihydro-quinoxalin-2-ylamino)-N-thiophen-2-ylmethyl-benzamideIC50280.0 [1]
4-[4-(2-Hydroxy-ethyl)-3-oxo-3,4-dihydro-quinoxalin-2-ylamino]-N-thiophen-2-ylmethyl-benzamideIC50320.0 [1]
N-[4-[(4-Methyl-3-oxoquinoxalin-2-yl)amino]phenyl]-1,2-oxazole-3-carboxamideIC50730.0 [1]
4-(4-Ethyl-3-oxo-3,4-dihydro-quinoxalin-2-ylamino)-N-thiophen-2-ylmethyl-benzamideIC50190.0 [1]
4-[[3-Oxo-4-(2-piperidin-1-ylethyl)quinoxalin-2-yl]amino]-N-(thiophen-2-ylmethyl)benzamideIC50420.0 [1]
1,4-Dihydropyridine-2,3-dicarboxylic acidKi1.6 [1]
4-(2-Benzoylamino-phenoxy)-phthalic acidIC50100000.0 [1]
4-(2-Chlorophenyl)-1-[(3,4-dichlorophenyl)methyl]-6-methyl-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC5041.0 [1]
1-Ethyl-4-(2-chlorophenyl)-5-(isopropylcarbamoyl)-6-methyl-1,4-dihydropyridine-2,3-dicarboxylic acidIC5012.9 [1]
4-(2-Chlorophenyl)-6-methyl-5-propan-2-yloxycarbonyl-1-(2,2,2-trifluoroethyl)-4H-pyridine-2,3-dicarboxylic acidIC5052.0 [1]
4-(2-Chlorophenyl)-1-ethyl-6-methyl-5-propan-2-yloxycarbonyl-4H-pyridine-3-carboxylic acidIC5015000.0 [1]
1-Ethyl-6-methyl-4-phenyl-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC501195.0 [1]
4-(2-Chlorophenyl)-1-[(2-chlorophenyl)methyl]-6-methyl-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC50178.0 [1]
1-Ethyl-4-(2-chlorophenyl)-5-(isobutylcarbamoyl)-6-methyl-1,4-dihydropyridine-2,3-dicarboxylic acidIC508.28 [1]
1-Ethyl-4-(2-chlorophenyl)-5-(benzylcarbamoyl)-6-methyl-1,4-dihydropyridine-2,3-dicarboxylic acidIC5010.61 [1]
4-(2-Chlorophenyl)-1-[(3-chlorophenyl)methyl]-6-methyl-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC5029.0 [1]
4-(2-Chlorophenyl)-6-methyl-1-[(3-nitrophenyl)methyl]-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC5010.0 [1]
4-(2-Chlorophenyl)-1-[(3,5-dichlorophenyl)methyl]-6-methyl-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC5037.0 [1]
4-(2-Chlorophenyl)-1-[(2,5-dichlorophenyl)methyl]-6-methyl-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC5091.0 [1]
4-(2-Chlorophenyl)-6-methyl-5-propan-2-yloxycarbonyl-1,4-dihydropyridine-2,3-dicarboxylic acidIC50172.0 [1]
4-(2-Chlorophenyl)-1-[(2,4-dichlorophenyl)methyl]-6-methyl-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC50185.0 [1]
4-(2-Chlorophenyl)-1-[(2,3-dichlorophenyl)methyl]-6-methyl-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC50233.0 [1]
4-(2-Chlorophenyl)-1-[(4-chlorophenyl)methyl]-6-methyl-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC506.0 [1]
1-Benzyl-4-(2-chlorophenyl)-6-methyl-5-propan-2-yloxycarbonyl-4H-pyridine-2,3-dicarboxylic acidIC5026.0 [1]
1-Ethyl-4-(2-chlorophenyl)-5-(ethylcarbamoyl)-6-methyl-1,4-dihydropyridine-2,3-dicarboxylic acidIC5019.9 [1]
(5R,6S,7S,8R,9R)-6,7,8-Trihydroxy-9-(hydroxymethyl)-1,3-diazaspiro[4.5]decane-2,4-dioneKi3000.0 [1]
4-{2-[(4-Chloro-pyridine-2-carbonyl)-amino]-4-fluoro-phenoxy}-phthalic acidIC50647.0 [1]
4-{4-Fluoro-2-[(4-nitro-pyridine-2-carbonyl)-amino]-phenoxy}-phthalic acidIC50109.0 [1]
4-(3-Benzoylamino-naphthalen-2-yloxy)-phthalic acidIC5012300.0 [1]
4-[3-(4-Ethyl-2-pyridinylcarbonylamino)-2-naphthyloxy]phthalic acidIC5029.0 [1]
4-{2-[(4-Cyano-pyridine-2-carbonyl)-amino]-phenoxy}-phthalic acidIC50167.0 [1]
4-{2-[(4-Iodo-pyridine-2-carbonyl)-amino]-phenoxy}-phthalic acidIC50468.0 [1]
4-{2-[(4-Methoxy-pyridine-2-carbonyl)-amino]-phenoxy}-phthalic acidIC50200.0 [1]
4-{2-[(4-Chloro-pyridine-2-carbonyl)-amino]-phenoxy}-phthalic acidIC50181.0 [1]
4-{3-[(Pyridine-2-carbonyl)-amino]-naphthalen-2-yloxy}-phthalic acidIC50844.0 [1]
4-[2-(4-Methoxy-2-pyridinylcarbonylamino)-3-fluorophenoxy]phthalic acidIC50110.0 [1]
4-[2-(4-Nitro-2-pyridinylcarbonylamino)-3-fluorophenoxy]phthalic acidIC509.0 [1]
4-[3-Fluoro-2-(3-nitro-benzoylamino)-phenoxy]-phthalic acidIC501860.0 [1]
4-[2-(4-Nitro-2-pyridinylcarbonylamino)phenoxy]phthalic acidIC5025.0 [1]
4-[3-[[4-(Trifluoromethyl)pyridine-2-carbonyl]amino]naphthalen-2-yl]oxyphthalic acidIC5080.0 [1]
4-{3-[(4-Methyl-pyridine-2-carbonyl)-amino]-naphthalen-2-yloxy}-phthalic acidIC5057.0 [1]
4-[3-(3-Nitro-benzoylamino)-naphthalen-2-yloxy]-phthalic acidIC50140.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Muscle glycogen phosphorylase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/muscle-glycogen-phosphorylase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Muscle glycogen phosphorylase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/muscle-glycogen-phosphorylase-inhibitors-ic50-ki.
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