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Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
1-(3-Chloropyridin-2-yl)-N-[5-chloro-6-(triazol-2-yl)pyridin-3-yl]piperidine-4-carboxamideIC504.0 [1], 50.0 [2], 90.0 [3]
1-(3-Aminopyridin-2-yl)-N-[5-chloro-6-(triazol-2-yl)pyridin-3-yl]piperidine-4-carboxamideIC507.0 [1], 80.0 [2], 90.0 [3]
beta-LapachoneIC501200.0 [1], 1900.0 [2]
PecazineIC50420.0 [1], 830.0 [2]
CID 16014601IC501620.0 [1], 3100.0 [2]
1-[2-Chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[6-(triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]ureaIC500.0 [1], 0.02 [2]
1-[4-[4-(Aminomethyl)pyrazol-1-yl]-3-chlorophenyl]-3-(2-chloro-7-propan-2-ylpyrazolo[1,5-a]pyrimidin-6-yl)ureaIC500.01 [1], 0.13 [2]
1-[2-Chloro-7-(oxolan-2-yl)pyrazolo[1,5-a]pyrimidin-6-yl]-3-[6-(triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]ureaIC500.0 [1], 0.09 [2]
1-[7-[(1S)-1-Methoxyethyl]-2-methylpyrazolo[1,5-a]pyrimidin-6-yl]-3-[5-(trifluoromethyl)pyridin-3-yl]ureaIC500.01 [1], 0.05 [2]
1-(2-Chloro-7-propan-2-ylpyrazolo[1,5-a]pyrimidin-6-yl)-3-[6-(1,1-dioxo-1,2-thiazolidin-2-yl)-5-(trifluoromethyl)pyridin-3-yl]ureaIC500.01 [1], 0.25 [2]
1-[2-Chloro-7-(1-cyclopropyl-2-methoxyethyl)pyrazolo[1,5-a]pyrimidin-6-yl]-3-[5-chloro-6-(triazol-2-yl)pyridin-3-yl]ureaIC500.01 [1], 0.03 [2]
N-(3-Chloro-4-fluorophenyl)-1-(3-cyanopyridin-2-yl)piperidine-4-carboxamideIC50420.0 [1], 2700.0 [2]
N-[3-Chloro-4-[3-(methylcarbamoyl)-1,2,4-triazol-1-yl]phenyl]-1-(3-chloropyridin-2-yl)piperidine-4-carboxamideIC5021.0 [1], 140.0 [2]
N-(3-Chloro-4-fluorophenyl)-1-(3-chloropyrazin-2-yl)piperidine-4-carboxamideIC50100.0 [1], 290.0 [2]
N-(5-Chloro-6-methoxypyridin-3-yl)-1-(3-chloropyridin-2-yl)piperidine-4-carboxamideIC5013.0 [1], 190.0 [2]
N-(3-Chloro-4-methylphenyl)-1-(3-chloropyridin-2-yl)piperidine-4-carboxamideIC5054.0 [1], 3700.0 [2]
N-(3-Chloro-4-fluorophenyl)-1-(3-chloropyridin-2-yl)piperidine-4-carboxamideIC5028.0 [1], 1350.0 [2]
N-[3-Chloro-4-(3,5-dimethyl-1,2,4-triazol-1-yl)phenyl]-1-(3-nitropyridin-2-yl)piperidine-4-carboxamideIC50184.0 [1], 640.0 [2]
1-(3-Chloropyridin-2-yl)-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]piperidine-4-carboxamideIC50340.0 [1], 3000.0 [2]
1-(3-Aminopyridin-2-yl)-N-(3-chloro-4-fluorophenyl)piperidine-4-carboxamideIC50100.0 [1], 420.0 [2]
1-(3-Aminopyridin-2-yl)-N-[3-chloro-4-(triazol-2-yl)phenyl]piperidine-4-carboxamideIC5035.0 [1], 110.0 [2]
N-(3-Chlorophenyl)-1-(3-chloropyridin-2-yl)piperidine-4-carboxamideIC50210.0 [1], 1590.0 [2]
N-(3-Chloro-4-fluorophenyl)-1-phenylpiperidine-4-carboxamideIC50820.0 [1], 3200.0 [2]
MI 2 MALT1 inhibitorIC503300.0 [1]
8-Methoxy-beta-lapachoneIC50600.0 [1]
8,9-Dimethoxy-2,2-dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dioneIC502300.0 [1]
4-[(2-Oxo-2-pyrrolidin-1-ylethyl)amino]naphthalene-1,2-dioneIC504100.0 [1]
2-[(3,4-Dioxonaphthalen-1-yl)amino]-N-(2-phenylethyl)acetamideIC503100.0 [1]
7-Fluoro-4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dioneIC5010000.0 [1]
7-Bromo-4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dioneIC5010000.0 [1]
7,8-Dimethoxy-2,2-dimethyl-3,4-dihydrobenzo[g]chromene-5,10-dioneIC5010000.0 [1]
8-Fluoro-2,2-dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dioneIC501500.0 [1]
8-Bromo-2,2-dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dioneIC509200.0 [1]
2,2-Dimethyl-5,6-dioxo-3,4-dihydrobenzo[h]chromene-8-carbonitrileIC501600.0 [1]
2,2-Dimethyl-8-nitro-3,4-dihydrobenzo[h]chromene-5,6-dioneIC50400.0 [1]
9-Methoxy-2,2-dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dioneIC509200.0 [1]
4-(2-Methoxyethylamino)naphthalene-1,2-dioneIC507800.0 [1]
4-(3-Pyrrolidin-1-ylpropylamino)naphthalene-1,2-dioneIC5011900.0 [1]
4-[3-(2-Oxopyrrolidin-1-yl)propylamino]naphthalene-1,2-dioneIC5014400.0 [1]
Tert-butyl N-[2-[(3,4-dioxonaphthalen-1-yl)amino]ethyl]carbamateIC5014900.0 [1]
4-[(1-Benzylpyrrolidin-3-yl)amino]naphthalene-1,2-dioneIC501500.0 [1]
4-[(1-Benzylpiperidin-4-yl)amino]naphthalene-1,2-dioneIC505400.0 [1]
2-[(3,4-Dioxonaphthalen-1-yl)amino]-N-methylacetamideIC503000.0 [1]
4-[2-(Dimethylamino)ethylamino]naphthalene-1,2-dioneIC501600.0 [1]
4-[(Propan-2-yl)amino]naphthalene-1,2-dioneIC5020400.0 [1]
4-(Dimethylamino)-1,2-naphthoquinoneIC502500.0 [1]
N-(3-Chloro-4-fluorophenyl)-1-pyridin-2-ylpiperidine-4-carboxamideIC501900.0 [1]
1-(3-Chloropyridin-2-yl)-N-cyclohexylpiperidine-4-carboxamideIC50100000.0 [1]
N-(3-Chloro-4-fluorophenyl)-1-(4-cyanopyridin-2-yl)piperidine-4-carboxamideIC509000.0 [1]
4-(Phenethylamino)naphthalene-1,2-dioneIC50100000.0 [1]
Chembl4129874IC50100000.0 [1]
Chembl4126140IC504700.0 [1]
N-(3-Chloro-4-fluorophenyl)-1-(2-methylpropyl)piperidine-4-carboxamideIC50100000.0 [1]
4-(2-Morpholin-4-ylethylamino)naphthalene-1,2-dioneIC5021900.0 [1]
9-Hydroxy-2,2-dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dioneIC509300.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/mucosa-associated-lymphoid-tissue-lymphoma-translocation-protein-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/mucosa-associated-lymphoid-tissue-lymphoma-translocation-protein-1-inhibitors-ic50-ki.
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